Boost efforts to elimiate tuberculosis by 2050
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Boost efforts to elimiate tuberculosis by 2050

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Use this presentation for your World TB Day activities and communications.

Use this presentation for your World TB Day activities and communications.

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Boost efforts to elimiate tuberculosis by 2050 Presentation Transcript

  • 1. World TB Day 24 March 2014 World TB Day 24 March 2014 Boost efforts to eliminate tuberculosis by 2050! ©CarlCordonnier
  • 2. World TB Day 24 March 2014 There is an urgent need for new anti- tuberculosis (TB) medicines with shorter and more effective treatment regimens and we must reach all patients, not only half of them and “half-way”. For the first time in 40 years, new TB drugs have become available and are in clinical trials – but their scope is limited to specific groups of patients. A key objective for new treatments should be to reduce treatment time from two years to two weeks, putting patients at the centre of care in the spirit of Health 2020. Zsuzsanna Jakab WHO Regional Director for Europe
  • 3. European strategic action plan on antibiotic resistance 2011–2016 Dr Guenael Rodier Director, Division of Communicable Diseases, Health Security and Environment A milestone for Europe Consolidated action plan on multidrug-resistant TB 2011–2015
  • 4. World TB Day 24 March 2014 New TB cases down by 5% yearly in Europe, but not enough to reach the elimination goal • Diagnosis and treatment scaled up to reach all patients with multidrug- resistant TB • Decline in new TB cases of 47 000 between 2011 and 2012 Greater action is required to eliminate TB globally, and address the emergence and spread of its resistant forms ©CarlCordonnier
  • 5. World TB Day 24 March 2014 Still nearly 1000 new TB cases a day: 1 in 10 dies • Estimated total of TB patients in the Region: over 500 000 • New TB cases estimated to occur per year: 353 000 • Deaths: 35 000, mostly in the eastern part of the Region ©CarlCordonnier
  • 6. World TB Day 24 March 2014 Europe not on track to halve TB mortality by 2015 (Millennium Development Goal 6) Targets for decline of TB incidence and prevalence likely to be achieved TB incidence TB prevalence TB mortality   3.9 2.3 = target 4.6 43 39.4 37 = target 71 Source: Global Tuberculosis report 2013. WHO/HTM/TB/2013.11
  • 7. World TB Day 24 March 2014 • Estimated total of new M/XDR-TB cases yearly: 76 400 • M/XDR-TB patients diagnosed: only 33 400 • Successful-treatment rate for MDR-TB patients: under 50% (target is 75%) Multidrug- and extensively drug-resistant TB (M/XDR-TB): biggest burden in the Region 76 400 65 000 85% 33 400 44% 49% Estimated number of M/Xdr-TB cases M/XDR-TB cases target for detection M/XDR-TB cases detected Treatment success rate of MDR-TB cohort Core indicators for monitoring the implementation of the M/XDR-TB action plan, WHO European Region, 2012 Source: European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2014. Stockholm: European Centre for Disease Prevention and Control; 2014. Estimated number of M/XDR-TB cases
  • 8. World TB Day 24 March 2014 Challenge of M/XDR-TB in the European Region • Over half of the countries with the highest rate of M/XDR-TB in the world are in the eastern part of the European Region. • Almost half of all previously treated TB patients develop M/XDR-TB. 3.6 16.0 2.3 9.2 9.4 11 11 13 14 20 22 23 23 23 24 26 35 20 45 23 31 43 32 44 56 32 50 56 55 49 62 62 68 69 0 20 40 60 80 Global average European Region average Bulgaria Georgia Armenia Latvia Lithuania Tajikistan Ukraine Estonia Azerbaijan Kazakhstan Russian Federation Uzbekistan Republic of Moldova Kyrgyzstan Belarus % MDR among TB cases (%), WHO European Region, 2012 Previously treated cases New cases Source: Global Tuberculosis report 2013. WHO/HTM/TB/2013.11
  • 9. World TB Day 24 March 2014 TB burden unequally distributed among countries • 85% of TB cases found in the 18 high-priority countries for TB control in the Region • Rate of TB cases in these countries: almost 8 times higher than in the rest of the Region 32 39 62 11 0 10 20 30 40 50 60 70 80 90 Casesper100000population TB notification rate, WHO European Region, 1980–2012 Notification rate (all countries) Estimated incidence (all countries) Notification rate (18 high priority countries) Notification rate (EU countries) 18 high-priority countries (85% of all TB cases): Armenia, Azerbaijan, Belarus, Bulgaria, Estonia, Georgia, Kazakhstan, Kyrgyzstan, Latvia, Lithuania, Republic of Moldova, Romania, Russian Federation, Tajikistan, Turkey, Turkmenistan, Ukraine, Uzbekistan. Source: European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2014. Stockholm: European Centre for Disease Prevention and Control; 2014.
  • 10. World TB Day 24 March 2014 TB can affect everyone, but is mainly linked to migration, social marginalization and imprisonment • 7.2% of the new TB cases in the Region are reported in prisoners • Prisoners have 26 times the risk of falling sick with TB of the general population © Maxim Dondiuk
  • 11. World TB Day 24 March 2014 Leading killer among people living with HIV • People living with HIV/AIDS have up to 34 times greater risk of TB co-infection. • About 13 000 TB cases with HIV co-infection were detected in the Region – 70% of the estimated total. • Less than two thirds were offered antiretroviral treatment. 2.8 2.8 3.4 4.8 6.0 5.4 6.1 0 1 2 3 4 5 6 7 2006 2007 2008 2009 2010 2011 2012 % Percentage of HIV among notified TB, WHO European Region, 2012 Source: European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2014. Stockholm: European Centre for Disease Prevention and Control; 2014.
  • 12. World TB Day 24 March 2014 One in three TB patients is not cured • 1 untreated person with TB or M/XDR-TB can infect 10–15 other people yearly. 10% of them develop the disease. • Anti-TB regimens are complex, toxic and inefficient in curing M/XDR-TB. • Adequate TB treatment will prevent M/XDR-TB. • The key objective of TB control is to reduce treatment time to less than 2 weeks. 66.1 7.9 8.4 5.7 11.9 Treatment outcomes (%) of new pulmonary laboratory-confirmed cases, WHO European Region, 2011 Successfully treated Died Failures Defaulters Not evaluated Source: European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2014. Stockholm: European Centre for Disease Prevention and Control; 2014.
  • 13. World TB Day 24 March 2014 Prevent the development of M/XDR-TB Scale up access to effective treatment Scale up access to early diagnosis Improve infection control Strengthen surveillance Expand management capacity of the programmes Address the needs of special populations Consolidated Action Plan to Prevent and Combat Multidrug- and Extensively Drug-resistant Tuberculosis
  • 14. World TB Day 24 March 2014 120 000 lives and US$ 12 billion could be saved by implementing the Consolidated Action Plan The goal is to contain the spread of drug-resistant TB by: • decreasing M/XDR-TB cases among previously treated cases by 20 percentage points; • detecting 85% (or 225 000) of M/XDR-TB patients; and • successfully treating at least 75% (127 000) of them. ©CarlCordonnier
  • 15. World TB Day 24 March 2014 Eliminating TB by 2050 requires putting patients at the centre of care • Early diagnosis and full treatment for all patients • Move from hospital to ambulatory care • New TB drugs, with shorter and more effective treatment regimen • New diagnostics and vaccines • Less stigma and more equity • More funds, better used ©CarlCordonnier
  • 16. World TB Day 24 March 2014 Thank you (www.euro.who.int/tuberculosis) World TB Day 24 March 2014 ©CarlCordonnier