Drug Eluting Coronary StentingTreatment

Drug Eluting Coronary Stenting treatment India at affordable low CostDrug Eluting Coronary Stenting In India The Food and Drug Administration (FDA), which monitors the use of medical devices, considers both bare-metal and drug-eluting stents to be safe and effective in most people. But, all stents involve some risk. Sometimes the angioplasty procedure itself can cause complications such as a heart attack, blood clots, bleeding or injury to the blood vessels. Both bare-metal and drug-eluting stents have a risk of clotting both early and late after implantation. It appears that in some people who get drug-eluting stents, there's a small increased risk of blood clots forming in the stent once the drug coating has been used up — sometimes a year or more after stent implantation.

This risk is still quite low; about 0.5 percent or less when stents are used for FDA-approved reasons. The risk appears to be slightly higher when drug-eluting stents are used for off-label uses, ranging from about 0.4 to 1.6 percent.Do drug-eluting stents increase risk of heart attacks ? An FDA advisory panel found that when drug-eluting stents are used "on-label" — meaning for specific situations approved by the FDA — there was no increased risk of heart attack or death with drug-eluting stents compared with bare-metal stents. However, about 60 percent of the time stents are used for "off-label" indications — meaning for reasons that, while appropriate, are not specifically spelled out in the FDA guidelines. When stents are used off-label, it's generally for more-complex cases, such as in someone who has multiple blockages and other complications.

The FDA panel said when drug-eluting stents are used off-label, there's a small but increased risk of blood clotting that can lead to heart attack and death. But, it's unknown if drug-eluting stents cause this increased risk or whether people in this group tend to be at higher risk in the first place. There are a variety of potential explanations for blood clots developing later after implantation. Much of it may have to do with how long a person takes anti-platelet medications — aspirin, clopidogrel (Plavix) — which help prevent blood clots from forming in the stents. If these medications are stopped earlier than recommended or an individual doesn't have an effective response to the anti-clotting medications, there can be problems. People also have varying healing times.

What's a stent ? Stents are metal mesh tubes inserted after an angioplasty into an artery that has become partially or completely blocked. Stents help prevent restenosis — when the artery becomes blocked again. Without the use of stents, about 30 percent of arteries become blocked again...So, bottom line, are drug-eluting stents safe or not ? Based on all presently available information, drug-eluting stents are safe and effective in most circumstances. The key is you must be willing to take your medications in the prescribed manner and for the prescribed duration to help ensure safety...

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