Peak & trough

9,826
-1

Published on

0 Comments
2 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
9,826
On Slideshare
0
From Embeds
0
Number of Embeds
2
Actions
Shares
0
Downloads
0
Comments
0
Likes
2
Embeds 0
No embeds

No notes for slide

Peak & trough

  1. 1. Peak & Trough Vancomycin is a glycopeptide antibiotic. It is a time dependent killer. The level has to stay above a minimum concentration for a length of time for the medication to be effective. Thus, Vancomycin doses should not be held while waiting for a trough level. Vancomycin peak levels are not routinely monitored, however if ordered by the MD, the peak should be drawn 1 hour after medication dose is complete. Exception – if the ordered dose of Vancomycin is 2 grams or more then obtain the peak 2 hours after the infusion is complete.
  2. 2. Peak & Trough (cont) Collect trough immediately prior to dose Blood must NOT be drawn from the line it was infusing in Blood is drawn from a different port, it is NOT drawn from the port it was infused in Do not draw a trough level while Vancomycin is infusing Do not wait for trough results before hanging antibiotic unless a specific order to wait for result is ordered by MD Administer antibiotic at prescribed rate so levels are accurate
  3. 3. Peak & Trough (continued)Gentamicin Gentamicin is an aminoglycoside antibiotic. It works differently. It is a concentration dependent killer. This means the higher the peak concentration, the larger the kill of microorganisms. Gentamicin can kill microorganisms after the concentration has decreased (this is called a post-antibiotic effect). Patients on Gentamicin are monitored to ensure that levels are adequate for therapy and to detect elevated levels that may be associated with a greater risk of ototoxicity and nephrotoxicity.
  4. 4. Peak & Trough (continued) Blood must NOT be drawn from the line it was infusing in Blood is drawn from a different port, it is NOT drawn from the port it was infused in Do not wait for trough results before hanging antibiotic unless specific order to wait for result is ordered by MD Administer antibiotic at prescribed rate so that peak levels will be accurate If dose is received to infuse over 30 minutes, collect peak 30 minutes after dose completion EXCEPTION – If the dose is ordered to infuse over 60 minutes, then the peak is drawn 15 minutes after the infusion is complete

×