Mahrous Article Summary
Iron Treatment after Upper Gastrointestinal
Bleeding - 2013 Nov.
Waleed Mahrous

Dr Waleed Kh. Mah...
OBJECTIVES
Dr Waleed Kh. Mahrous

BACKGROUND:
 Nonvariceal acute upper gastrointestinal
bleeding (AUGIB) is often accompa...
METHODS
Dr Waleed Kh. Mahrous

 97 patients with nonvariceal AUGIB and
anemia were enrolled in a doubleblind, placebo-con...
RESULTS
 From week 4 onwards, patients receiving treatment

had significantly higher haemoglobin levels
compared with pat...
CONCLUSIONS
 Iron treatment is effective and

essential for treating anemia after
nonvariceal acute upper
gastrointestina...
Upcoming SlideShare
Loading in …5
×

Mahrous Article Summary - 2 - Iron Treatment after Upper Gastrointestinal Bleeding - 2013 Nov.

0 views
437 views

Published on

Mahrous Article Summary - 2 - Iron Treatment after Upper Gastrointestinal Bleeding - 2013 Nov.

Published in: Health & Medicine, Technology
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
0
On SlideShare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
3
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Mahrous Article Summary - 2 - Iron Treatment after Upper Gastrointestinal Bleeding - 2013 Nov.

  1. 1. Mahrous Article Summary Iron Treatment after Upper Gastrointestinal Bleeding - 2013 Nov. Waleed Mahrous Dr Waleed Kh. Mahrous http://www.ncbi.nlm.nih.gov/pubmed/24251969
  2. 2. OBJECTIVES Dr Waleed Kh. Mahrous BACKGROUND:  Nonvariceal acute upper gastrointestinal bleeding (AUGIB) is often accompanied by post-discharge anemia. AIM:  To investigate whether iron treatment can effectively treat anemia and to compare a 3-month regimen of oral iron treatment with a single administration of intravenous iron prior to discharge. Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html http://www.ncbi.nlm.nih.gov/pubmed/24251969
  3. 3. METHODS Dr Waleed Kh. Mahrous  97 patients with nonvariceal AUGIB and anemia were enrolled in a doubleblind, placebo-controlled, randomised study.  The patients were allocated to one of three groups, receiving a single intravenous administration of 1000 mg of iron; oral iron treatment, 200 mg daily for 3 months; or placebo, respectively. The patients were followed up for 3 months. Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html http://www.ncbi.nlm.nih.gov/pubmed/24251969
  4. 4. RESULTS  From week 4 onwards, patients receiving treatment had significantly higher haemoglobin levels compared with patients who received placebo only.  At the end of treatment, the proportion of patients with anemia was significantly higher in the placebo group (P < 0.01) than in the treatment groups.  Intravenous iron appeared to be more effective than oral iron in ensuring sufficient iron stores. Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html http://www.ncbi.nlm.nih.gov/pubmed/24251969
  5. 5. CONCLUSIONS  Iron treatment is effective and essential for treating anemia after nonvariceal acute upper gastrointestinal bleeding.  The route of iron supplementation is less important in terms of the increase in haemoglobin levels.  Iron stores are filled most effectively if intravenous iron supplementation is administered . Dr Waleed Kh. Mahrous http://www.ncbi.nlm.nih.gov/pubmed/24251969

×