COPD : Defination Emphysema, an anatomically defined condition characterized by destruction and enlargement of the lung alveoli Chronic bronchitis, a clinically defined condition with chronic cough and phlegm Small airways disease, a condition in which small bronchioles are narrowed. COPD is present only if chronic airflow obstruction occurs; chronic bronchitis without chronic airflow obstruction is not included within COPD.
Global Strategy for Diagnosis, Management and Prevention of COPD Manage Stable COPD: Pharmacologic Therapy (Medications in each box are mentioned in alphabetical order, and therefore not necessarily in order of preference.)Patient Recommended Alternative choice Other Possible First choice Treatments LAMA SAMA prn or A or LABA Theophylline SABA prn or SABA and SAMA LAMA SABA and/or SAMA B or LAMA and LABA Theophylline LABA ICS + LABA LAMA and LABA or or LAMA and PDE4-inh. or SABA and/or SAMA C LAMA LABA and PDE4-inh. Theophylline ICS + LABA ICS + LABA and LAMA or Carbocysteine and/or ICS+LABA and PDE4-inh. or D SABA and/or SAMA LAMA LAMA and LABA or Theophylline LAMA and PDE4-inh.