Curcumin, a yellow component of turmeric or currypowder, however, is an exception. Almost 2000papers have been published on the subject. Itsmechanism of action can be compared to inhibitorsof cyclooxygenase-2 (Celebrex), HER2(Herceptin), TNF(Enbrel, Humira, Remicade), EGFR (Erbitux andIressa), and vascular endothelial cell growth factor(Avastin), all of which have been approved forhuman use by the FDA.
Turmeric’s main ingredient, curcumin, has been shownto have a wide array of antioxidant and anti-inflammatory effects. Indeed, eating turmeric in theirdaily curries appears to be one of the main reasonsthat elderly citizens of India have very low rates ofAlzheimer’s disease. Curcumin incorporates itself intocell membranes and makes them more orderly. Thisallows the membranes to more effectively control theflow of substances in and out of cells, which improvescells resistance to infection and malignancy.
• Curcumin is effective in reducing the incidence of cholesterol gall stone.• Reduce the cholesterol crystal growth rate and the cholesterol crystal concentration.• Curcumin is found to be effective in preventing the inflammation induced increase in rat liver enzymes.
It has been estimated that the average daily intake of turmeric in the Indiandiet is about 2-2.5g which equates to about 60-100mg of curcumin daily.Curcumin at a dose of 1.8g/kg/day was given to rats and 0.9g/kg/day tomonkeys with no toxicity or adverse events in India.No of Capsules per day – 2 Capsules. • Vista Nutritions Turmeric Curcumin 300mg -- 60 Capsules • Vista Nutritions Turmeric Curcumin Ext 300mg -- 120 Capsules • Vista Nutritions Turmeric Curcumin Ext 300mg -- 240 Capsules • Vista Nutritions Curcumin 475mg -- 120 Capsules • Vista Nutritions Curcumin 475mg -- 240 Capsules. • Vista Nutritions Turmeric Root Ext 500mg -- 120 Capsules • Vista Nutritions Turmeric Root Ext 500mg -- 240 Capsules
Curcumin is found to be effective in preventing the inflammation induced increase in rat liver enzymes such as serum glutamic axaloacetic transamilase and serum glutamic pymvic transamilase [Srimal & Dhawan 1973; Susan & Rao 19911. Curcumin is a potent scavenger of active oxygen species including superoxide, hydroxyl radical and nitric oxide, which are implicated in inflanimation. Studies show that it is a good scavenger of hydroxyl radical at high concentrations but at low concentrations activated the Fenton system to generate an increased amount of hydroxyl radical.*These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.