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CATRA Presentation at SIGGRAPH 2011.

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- 1. CATRA: Interactive Measuring and Modeling of Cataracts<br />Vitor F. Pamplona Erick B. Passos Jan Zizka Manuel M. Oliveira Everett Lawson Esteban CluaRameshRaskar<br />MIT Media Lab – Camera Culture<br />
- 2. CATRA: Quantitative Maps for <br />Self-assessment of Early Cataracts<br />
- 3. NETRA: Near Eye Tool for Refractive Assessment<br />Vitor Pamplona , Ankit Mohan, Manuel Oliveira, RameshRaskar, ACM SIGGRAPH 2010<br />
- 4. Main Cause of Preventable Blindness<br />
- 5.
- 6. Slit-Lamp Microscope<br />
- 7.
- 8. Computational Ophthalmology<br />
- 9. Observing Sub-aperture<br />Scattering Profile<br />(Point Spread Function)<br />Clear Section<br />Cataract-Affected Section<br />Subject’s View<br />
- 10. Four Stages of Interaction<br />Occlusion<br />Scattering<br />Opacity Map<br />(position, size)<br />Attenuation Map<br />(brightness)<br />Contrast Map<br />(contrast)<br />PSF Map<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 11.
- 12.
- 13.
- 14. Four Stages of Interaction<br />Occlusion<br />Scattering<br />Opacity Map<br />(position, size)<br />Attenuation Map<br />(brightness)<br />Contrast Map<br />(contrast)<br />PSF Map<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />0.6mm<br />C<br />C<br />C<br />3mm<br />
- 15. ForwardScatteringSensedonFovea<br />Testing <br />Sections<br />Projection on the Fovea<br />LCD1<br />Lens<br />LCD2<br />Light Box<br />
- 16. ForwardScatteringSensedonFovea<br />Testing <br />Sections<br />Projection on the Fovea<br />LCD1<br />Lens<br />LCD2<br />Light Box<br />
- 17. Testing Sections of the Eye Lens<br />LCD1<br />Lens<br />LCD2<br />
- 18. Trading Resolution for Brightness<br />Testing Section<br />Collimated Beams<br />LCD1<br />Lens<br />LCD2<br />
- 19. Healthy Eye Point Spread Function = Peak<br />Eye<br />Visual Representation<br />PSF<br />
- 20. Mild Cataracts Point Spread Function <br />Eye<br />Visual Representation<br />PSF<br />
- 21. Advanced Cataracts Point Spread Function <br />Eye<br />Visual Representation<br />PSF<br />
- 22. CATRA: Measuring, Modeling and Simulation<br />σ<br />Peak<br />and simulate vision<br />We want to map the aperture<br />to estimate PSF<br />
- 23. Cataract Screening<br />Presence of Cataracts<br />(Binary Answer)<br />
- 24. Detecting the Presence of Cataracts<br />Moving patterns <br />on LCD1<br />LCD1<br />LCD2<br />
- 25. Detecting the Presence of Cataracts<br />LCD1<br />LCD2<br />
- 26. Detecting the Presence of Cataracts<br />LCD1<br />LCD2<br />Eye lens<br />
- 27. Detecting the Presence of Cataracts<br />LCD1<br />LCD2<br />Eye lens<br />Perceived Image<br />
- 28. Cataract Screening<br />Presence of Cataracts<br />(Binary Answer)<br />
- 29. Interactive Techniques and Maps<br />Presence of Cataracts<br />(Binary Answer)<br />Position, Size and Shape<br />(Opacity Map)<br />
- 30. Estimating an Opacity Map<br />Moving patterns <br />on LCD1<br />LCD1<br />LCD2<br />
- 31. Interactive Techniques and Maps<br />Presence of Cataracts<br />(Binary Answer)<br />Position, Size and Shape<br />(Opacity Map)<br />
- 32. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Presence of Cataracts<br />(Binary Answer)<br />Position, Size and Shape<br />(Opacity Map)<br />
- 33. Estimating Attenuation Maps<br />Decreasing <br />Brightness <br />on the clear path<br />LCD1<br />LCD2<br />
- 34. Estimating Attenuation Maps<br />Decreasing <br />Brightness <br />on the clear path<br />Same Perceived<br />Brightness <br />LCD1<br />LCD2<br />
- 35. Estimating Attenuation Maps<br />Decreasing Intensity <br />of the Clear Path<br />To Match Brightness<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />
- 36. Estimating Attenuation Maps<br />Decreasing Intensity <br />of the Clear Path<br />To Match Brightness<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />
- 37. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Presence of Cataracts<br />(Binary Answer)<br />Position, Size and Shape<br />(Opacity Map)<br />
- 38. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Presence of Cataracts<br />(Binary Answer)<br />Position, Size and Shape<br />(Opacity Map)<br />Peak<br />
- 39. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Presence of Cataracts<br />(Binary Answer)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />Position, Size and Shape<br />(Opacity Map)<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 40. Contrast Test<br />Increasing Contrast<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />Rotated Low Contrast Letter C<br />
- 41. Contrast Test<br />Increasing Contrast<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />Rotated Low Contrast Letter C<br />
- 42. Contrast Test<br />Increasing Contrast<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />Rotated Low Contrast Letter C<br />
- 43. Contrast Test<br />Increasing Contrast<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />Rotated Low Contrast Letter C<br />Press the right key<br />
- 44. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Presence of Cataracts<br />(Binary Answer)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />Position, Size and Shape<br />(Opacity Map)<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 45. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Presence of Cataracts<br />(Binary Answer)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />Position, Size and Shape<br />(Opacity Map)<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />C<br />C<br />C<br />C<br />C<br />σ<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 46. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Sub-aperture <br />PSF Match<br />(PSF Map)<br />Presence of Cataracts<br />(Binary Answer)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />Position, Size and Shape<br />(Opacity Map)<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 47. Point Spread Function Matching<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />
- 48. Point Spread Function Matching<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />
- 49. Point Spread Function Matching<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />
- 50. Point Spread Function Matching<br />Perceived Image<br />LCD1<br />LCD2<br />Eye<br />Sub-aperture <br />Point Spread Function<br />
- 51. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Sub-aperture <br />PSF Match<br />(PSF Map)<br />Presence of Cataracts<br />(Binary Answer)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />Position, Size and Shape<br />(Opacity Map)<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 52. Interactive Techniques and Maps<br />Brightness Test<br />(Attenuation Map)<br />Sub-aperture <br />PSF Match<br />(PSF Map)<br />Presence of Cataracts<br />(Binary Answer)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />Position, Size and Shape<br />(Opacity Map)<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />C<br />C<br />C<br />C<br />C<br />σ<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 53. Contrast Tests when High-Attenuated<br />Brightness Test<br />(Attenuation Map)<br />C<br />C<br />C<br />High Attenuation<br />Low Attenuation<br />C<br />C<br />C<br />C<br />C<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />Sub-aperture <br />PSF Match<br />(PSF Map)<br />Peak<br />C<br />C<br />C<br />C<br />C<br />Peak<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 54. Reducing Search Space for PSF<br />Brightness Test<br />(Attenuation Map)<br />Sub-aperture <br />PSF Match<br />(PSF Map)<br />Presence of Cataracts<br />(Binary Answer)<br />Low Attenuation<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />Position, Size and Shape<br />(Opacity Map)<br />Sub-aperture<br />Contrast Test<br />(Contrast Map)<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />High Attenuation<br />C<br />C<br />C<br />
- 55. DLP-Mask Prototype<br />High Contrast<br />DLP Projector<br />Mask<br />Lens<br />Eye<br />
- 56.
- 57. Dual Monitor Stack<br />
- 58. Dual Monitor Stack<br />
- 59. Dual Monitor Stack<br />Lens<br />Medical Monochrome Monitors <br />LCD Stack<br />
- 60. Cell Phone Prototype<br />Lens<br />Pinhole <br />Mask<br />
- 61. Validation using Cameras<br />Thin Diffuser to Simulate Cataracts<br />Estimated Attenuation Map<br />Estimated PSF Map<br />
- 62. Validation using Cameras<br />Estimated<br />Opacity Map<br />Measured Attenuation<br />(Pictures)<br />Estimated <br />Attenuation<br />(User Interaction)<br />Simulated Cataract<br />
- 63. Scratching Contact Lenses<br />Advanced <br />Cataracts<br />Mild<br />Cataracts<br />Early<br />Cataracts<br />Measured: 0.5mm2<br />Estimated: 0.45mm2<br />
- 64. Elderly Evaluation<br />
- 65. Rendering Cataract Effects<br />
- 66. Eye’s PSF = Summation of Sub-aperture PSF’s<br />For the point of <br />focus only<br />
- 67. Depth-dependent PSF<br />Far<br />Closer<br />Focal Point<br />
- 68. Scene for Simulation<br />Depth Map<br />
- 69. Picture with Cataract Lenses<br />
- 70. Simulation with Estimated PSF<br />
- 71.
- 72.
- 73.
- 74. Bokeh Effect<br />
- 75. Limitations<br />Active user participation<br />One clear light path<br />Retinal diseases<br />Patience and concentration <br />are required to follow steps<br />
- 76. Future Clinical Tests<br />Clinical Testing Partners<br />for CATRA<br />Last year’s NETRA Prototypes<br />(29 partners in 14 countries)<br />
- 77.
- 78.
- 79.
- 80.
- 81.
- 82.
- 83.
- 84.
- 85.
- 86.
- 87.
- 88.
- 89.
- 90.
- 91.
- 92.
- 93.
- 94. Acknowledgments<br />Bruce<br />Sherleen<br />Shrikant<br />Don<br />Rob<br />Caio<br />Tiago<br />Tyler<br />Fabiano<br />
- 95. Computational Ophthalmology<br />A Co-design of Optics and CG for Measuring Cataracts<br />Forward Scattering<br />Foveal Image<br />Four-stage Interactive Maps<br />A Radar for the Cloud Cover<br />Better than Subjective Rating<br />Simulation of an individual’s cataract-affected eye<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 96. CATRA: Quantitative Maps for <br />Self-assessment of Early Cataracts<br />More at: eyecatra.com<br />
- 97.
- 98. Mass-use Devices Scientific Instruments<br />
- 99. EyeNETRA Initiative<br />
- 100. EyeCATRA.com<br />C<br />C<br />C<br />LCD2<br />LCD1<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />C<br />
- 101. NETRA Near Eye Tool for Refractive Assessment<br />Vitor Pamplona, Ankit Mohan, Manuel Oliveira, Ramesh Raskar SIGGRAPH 2010<br />
- 102. Preventable Blindness<br />
- 103.
- 104.
- 105. Cataract Types<br />Nuclear<br />Sub-capsular<br />Cortical<br />
- 106. Cataract Types<br />Nuclear<br />Sub-capsular<br />Cortical<br />
- 107. Cataract Types<br />Nuclear<br />Sub-capsular<br />Cortical<br />
- 108. Cataract Types<br />Easier to detect<br />Nuclear<br />Sub-capsular<br />Cortical<br />
- 109.
- 110. CATRA: Quantitative Maps for <br />Self-assessment of Early Cataracts<br />Unique mappingtool for <br />size and density of eye opacities<br />

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