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Veterinary Oral Surgery for Dogs and Cats Part II
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Veterinary Oral Surgery for Dogs and Cats Part II

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Veterinary oral surgery for dogs and cats.

Veterinary oral surgery for dogs and cats.

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  • Per la chirurgia orale degli umani (e non animali!), rivolgersi al chirurgo dr. Giuseppe Spinelli
    http://www.giuseppespinelli.it/chirurgia-orale.html
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  • Oral SCC Therapy: Single modality therapy = 60-90 days NC Postorino et al; JAHHA Sept ‘93 Mandibulectomy and RT = 12-14 months CA Hutson et al; JAVMA Sept ‘92 Controversial amongst oncologists Not been able to be reproduced Most oncologists feel median survival = 4-6 months Tri-modality therapy (sx/RT/chemo) Being investigated presently Anecdotally appears to be 6-9 months 1 year survival rarely exceeds 10% in cats following any modality.
  • Oral SCC Generally POOR - GRAVE prognosis Human HNSCC (head & neck SCC) Also extremely invasive w/poor prognosis Overexpress EGFR (epidermal growth factor receptor) Increased growth rate Increased chemoresistance Increased radioresistance EGFR inhibitors alone in people = responses EGFR inhib + chemo/RT = dramatic responses
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