HIV/AIDS              Elaine Kauschinger            PhD, MS, ARNP, FNP-BC         Assistant Professor of ClinicalLead Facu...
Part 3: Clinical Management of         HIV Infection
Life cycle of the HIV virus
Highly Active Antiretroviral Therapy                 (HAART)6 classes of HIV medications:•All patients need to take a “coc...
DHHS Guidelines: When to       Initiate Medications   All patients with a CD4 counts between    350 & 500 cells/mm3   Al...
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Hiv aids  part 3
Hiv aids  part 3
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Hiv aids part 3

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  • The upper curve on the line graph represents the estimated number of AIDS diagnoses in the United States and dependent areas from 1985-2008; the lower curve represents the estimated number of deaths of adults and adolescents with an AIDS diagnosis during this time period. The peak in AIDS diagnoses during 1993 can be associated with the expansion of the AIDS surveillance case definition implemented in January 1993. The overall declines in new AIDS cases and deaths of persons with AIDS are due in part to the success of highly active antiretroviral therapies, introduced in 1996. In recent years, AIDS diagnoses and deaths of persons with AIDS have continued to decrease.All displayed data have been estimated. Estimated numbers resulted from statistical adjustment that accounted for reporting delays, but not for incomplete reporting.  Deaths of persons with an AIDS diagnosis may be due to any cause (may not be AIDS-related). Deaths of persons with an AIDS diagnosis are classified as adult or adolescent based on age at death.
  • Hiv aids part 3

    1. 1. HIV/AIDS Elaine Kauschinger PhD, MS, ARNP, FNP-BC Assistant Professor of ClinicalLead Faculty, Family Nurse Practitioner Program University of Miami School of Nursing & Health Studies
    2. 2. Part 3: Clinical Management of HIV Infection
    3. 3. Life cycle of the HIV virus
    4. 4. Highly Active Antiretroviral Therapy (HAART)6 classes of HIV medications:•All patients need to take a “cocktail” of 3drugs. 1. Nucleoside/nucleotide analogs (“nukes”) 2. Nonnucleoside reverse transcriptase inhibitors (NNRTI’s) (“non-nukes”) 3. Protease inhibitors (“PI’s”) 4. Fusion entry inhibitors 5. CCR5 Inhibitors
    5. 5. DHHS Guidelines: When to Initiate Medications All patients with a CD4 counts between 350 & 500 cells/mm3 All patients with a history of an AIDS- defining illness or with a CD4 count <350 cells/mm3 Patients with CD4 counts >500 cells/mm3 • 50% of panel recommendation therapy while 50% view therapy as optional – NA- ACCORD study; ART Cohort Collaboration
    6. 6. Please continue to part 4
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