김이산 메인 Benefits of a silica-based fluoride toothpaste containingo-cymen-5-ol, zinc chloride and sodium fluoride - 김이산Presentation Transcript
Benefits of a silica-based fluoride toothpastecontainingo-cymen-5-ol, zinc chloride and sodium fluoride2013. 5. 31발표자 : 폴리클 3 조17 번 김이산
IntroductionPeople use toothpaste in conjunction with tooth brushing not only toclean teeth and control the build up of plaque but to gain access toother oral health benefits- Anti caries, gum health and malodour control Toothpate often contain specific ingredients- The use of fluoride as an anti-caries agent being the mostwidespread.
Fluoride toothpaste and cariesCochrane systematic review of fluoride toothpaste- Supported by more than half a century of research ,the benefits of fluoride toothpastes are firmlyestablished.- The trials are of relatively high quality and provide clearevidence that fluoride toothpaste are efficacious inpreventing caries.
Fluoride toothpaste and cariesCochrane systematic review of fluoride toothpaste- 1000ppm fluoride is the minimum concentration that isthe minimum concentration that is proven to beeffectiveagainst caries based on data from caries clinical trials.- Further, increase in the anti-caries effectiveness oftoothpastes have been associted with increaingfluorideconcentration.
Fluoride toothpaste and caries The anti-caries action of fluoride results from itsfavourable effect on tooth remineralisation anddemineralisation. It is generally accepted that fluoride ions promotethe remineralisation of tooth enamel, increase apatitestructural stability and reduce the rate ofdemineralization
Fluoride toothpaste and caries Several sources of fluoride currently utilised inmarketeddentifrices.- NaF , MFP , SnF2 ,- organic fluorides such as amine fluoride. Particularly between the two most widely studiedsourcesNaF and MFP.- NaF dentifrices are slightly more effective than thoseemploying MFP
Toothpaste and gum health Plaque-induced gingivitis in the absence of clinicalattachment loss, is the most common form ofperiodontaldisease. Incorporation of additional antimicrobial actives intoothpaste as an adjunct to mechanical plaque controlis a convenient way to provide additional protectionagainst plaque and gingivitis.
Toothpaste containing 0.1% o-cymen-5-ol and 0.6%Zinc chloride. These toothpaste provide a convenient way to provideadditional protection for 50-90% of the adultpopulationthat fits into peoples everyday oral care routines. The unique combination of zinc chloride and o-cymen-5-ol has resulted in a spectrum of antimicrobial activitygreater than for each of the ingredients alone.
Toothpaste containing 0.1% o-cymen-5-ol and 0.6%Zinc chloride. When seeking to establish the anti-caries efficacy of a totally Newanti-caries system, a caries clinical trial is desirable.- However, the high cost and duration of such trials hasled tothe development of alternative methods.These methods generally described as bioequivalancestudies.Bioavailable fluoride studies were conducted throughout thedevelopment of the o-cymen-5-ol and zinc chloride toothpaste.
Conclusion Toothpaste that give additional benefits beyond the primaryreasons for use such as clean teeth plaque control and fluoridedelivery for anti-caries activity shuld be designed not tocompromise these benefits. o-cymen-5-ol and zinc chloride can be incorporated intotoothpaste to give addition benefits beyond that of standardtoothpaste without compromise the benefits of a standardtoothpaste