Opening up the Research Communications Ecosystem
Upcoming SlideShare
Loading in...5

Opening up the Research Communications Ecosystem



talk by Tim Clark at Beyond the PDF workshop, San Diego CA, 19-21 Jan 2011

talk by Tim Clark at Beyond the PDF workshop, San Diego CA, 19-21 Jan 2011



Total Views
Views on SlideShare
Embed Views



0 Embeds 0

No embeds



Upload Details

Uploaded via as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
Post Comment
Edit your comment

Opening up the Research Communications Ecosystem Opening up the Research Communications Ecosystem Presentation Transcript

  • Tim Clark Harvard Medical School & Massachusetts General Hospital January 19, 2011 Copyright 2011 Massachusetts General Hospital. All rights reserved.
    • … [we] parked our egos and
    • intellectual-property noses
    • outside the door and agreed
    • that all of our data would be
    • public immediately.”
    • John Trojanowski, MD, PhD
    • U Penn Medical School
    Sharing of Data Leads to Progress on Alzheimer’s , NY Times, 12 Aug 2010
  • MCI progressors non progressors PET imaging of PIB (radiolabelled compound binds amyloid beta A4 protein) MRI imaging of brain structure showing loss of hippocampal volume Brain. 2010 Nov;133(Pt 11):3336-3348 . = 218 subjects +
  • create hypothesis design experiment run experiment collect data interpret data share interpretations synthesize knowledge
  • dopaminergic pathway α-synuclein, β-amlyoid α-synuclein, Tau chr 16p11.2 CNV chr 16p11.2 CNV CRF, glutaminergic system, dopamine, amygdala … Alzheimer Disease Parkinson’s Disease Schizophrenia Autism Bipolar Disorder Drug Addiction Huntington’s Disease ALS Depression SIRT2
  • 1667 2010 Printing Press Web
  • We scientists do not attend professional meetings to present our findings ex cathedra, but in order to argue. John Polanyi, FRS
  • Genes Proteins Biological Processes Chemical Compounds Antibodies Cells Brain anatomy …
  • Text Shared metadata
  • Dr. Paolo Ciccarese – Oct 8, 2010
    • <rdf:Description rdf:about=&quot;;>
    • <rdf:type rdf:resource=&quot;;/>
    • <rdfs:label>Species</rdfs:label>
    • </rdf:Description>
    • <rdf:Description rdf:about=&quot;;>
    • <rdf:type rdf:resource=&quot;;/>
    • <pav:createdOn rdf:datatype=&quot;java:java.sql.Timestamp&quot;>2011-01-06T13:58:29.000000000-05:00</pav:createdOn>
    • </rdf:Description>
    • <rdf:Description rdf:about=&quot;;>
    • <rdf:type rdf:resource=&quot;;/>
    • <foaf:mbox></foaf:mbox>
    • <foaf:firstName>Paolo</foaf:firstName>
    • <foaf:img>
    • </foaf:img>
    • <foaf:lastName>Ciccarese</foaf:lastName>
    • <foaf:homepage></foaf:homepage>
    • <foaf:name>Paolo Ciccarese</foaf:name>
    • </rdf:Description>
    • <rdf:Description rdf:about=&quot;;>
    • <pav:createdBy rdf:resource=&quot;;/>
    • </rdf:Description>
    • <rdf:Description rdf:about=&quot;;>
    • <rdf:type rdf:resource=&quot;;/>]
    • SWAN Annotation
    • Utopia Annotation
  • Parkinson’s Disease Stem Cell Technology
    • Opening up the static document on the Web
    • Integrating the Web of documents with the Web of data (semantic web)
    • Exploiting synergies with textmining apps
    • Creating an ecosystem of semantic metadata on scientific publications
    • New models of Semantic Publishing in Science
    • Guest Editors:
      • P Bourne, T Clark, A de Waard,
      • C Goble, S Pettifer, D Shotton
    • Call for papers next week
    • Send us your best work!