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Medistein is a new startup for medical devices. Our vision is to improve the health outcomes of mobile and home-based patients by developing portable, user-friendly and state of the art healthcare …

Medistein is a new startup for medical devices. Our vision is to improve the health outcomes of mobile and home-based patients by developing portable, user-friendly and state of the art healthcare products.

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  • 1. AlokNarula | Dr. Felix Beyeler | JeetNath October, 2013 CONFIDENTIAL | Cell: +1.226-338-7433 | Skype:Tuxwarrior 1
  • 2. Mission / Vision To improve the health outcomes of mobile and home-based patients by developing portable, user-friendly and state of the art healthcare products. Our 1st product - Portable Medication Unit (PMU) - fulfills this vision by solving the problem of medication non-compliance. CONFIDENTIAL 2
  • 3. Market / Problem 90million 50% of the > 65 yrs had two or more Chronic Diseases 24 million had Cancer 14 million 78 million had Dementia b/w 20 - 79 yrs had confirmed Diabetes During 2009, in 30 OECD countries of North America, Europe, Asia and Oceania 1.5 million were waiting for Kidneys However, only 50% of all patients / 25% of all elderly took medications as prescribed. CONFIDENTIAL 3
  • 4. Market / Problem During 2009 Medication Non-compliance Caused premature death of 125,000 People in U.S. 200,000 People in Europe Resulted in an economic loss of $290 billion In U.S. €125 billion $ € In Europe The market opportunity for medication compliance devices in 30 OECD countries is around 100 million people. We believe that our product can capture 10 percent (10 million people) of this market. CONFIDENTIAL 4
  • 5. Market / Problem To Improve Medication Compliance Many devices have been built or These devices are But Too Big Too Complicated to carry to setup Patented Unreliable CONFIDENTIAL 5
  • 6. Product / Solution Alerts Eliminates medication mix-up / incorrect medication by working with a standard 33mm drug enclosure PMU the patient to take medication and records any missed doses Monitors Calibrates doseandreminders through a Smart Card / Health Cloud interface &Barcode / RFID scanner Portable Medication Unit (PMU) - Handy - Intelligent - Extensible CONFIDENTIAL drug consumption and automatically reorders medication before it runs out 6
  • 7. Technology / Secret Sauce Measures Can be embedded medication compliance by detecting weight change of medication / container in pill bottles, vial boxes and pill organizers Micro-force Sensor Detects drug overdose and under dose, in addition to a regular dose CONFIDENTIAL Works with pills, powder, liquid 7
  • 8. Business Model KEY PARTNERS KEY ACTIVITIES Value Proposition Customer Benefits Target Customer Higher Pharma Sales Pharmaceutical Cos. Clinical Research Org. Develop Medical Devices Develop Interoperability Bridge Develop Medical Apps Medical Device Cos. Apps to share and record data, information & statistics KEY RESOURCES • team management Mobile N/W Operators Portable and user friendly medication compliance device (PMU) Interoperability bridge to interface the PMU with external devices Patent Startup Capital Hospitals A-Grade Staff Tool for Clinical Research Government Strategic Partnership with Micro-force sensor Developer Regulatory Testing / FDA Compliance Extra Revenue for Mobile Network Operators Organ Transplant Patients Cancer Patients Distribution Channel Pharmacy Benefit Managers Dementia Patients Health Insurance Providers Patients with Motor Neuron Diseases (Parkinson’s, Alzheimer's) Seniors Healthcare Providers REVENUE STREAMS Administration IT Infrastructure Prototyping Sales & Marketing S/W Tools & Lab Equipment CONFIDENTIAL Chronically Ill (Diabetic, CVD, Hypertensive) Clinical Research Organizations Retirement Communities COST CENTERS Staff Salaries Better Health, Reduced Mortality, Lower Medical Expenses Patents Revenue from Interoperability Bridge Sales of Medical Devices Revenue from Medical Apps Co-branding with Pharmaceutical Companies Revenue Sharing Partnerships with Mobile Network Operators Royalty Revenue from Rx Reorders 8
  • 9. Bootstrapping Strategy 1. Build PMU Prototype Components Cost Time Frame A  Microforce Sensor  Electronic Board $25,000 2 – 4 Months B  iOS App $25,000 2 Months C  Cloud Database $10,000 1 Month $60,000 6 Months Totals Implementation: The PMU prototype will feature a clamp (to hold a 33-mm medication container) and a pocket (to insert an IPhone). The IPhone will read prescription data from a cloud and configure the PMU. 3. Raise Capital CONFIDENTIAL A B IPHONE Task 2. Demo PMU Prototype C PMU 4. Build Team / Partnerships 9
  • 10. Customer Acquisition Stages Trials Launch Growth Maturity Channels Government Initiatives Internet Advertising Distribution Partners Co-branding Clinical Research Organizations Veterans Health Administration (U.S.) GoogleAdwords Pharmacy Benefit Managers Pharma Companies Quintiles National Health Service (U.K.) Health Insurance Providers Medical Devices Companies Covance Medcom (Denmark) Seniors Healthcare Providers National Institutes of Health (U.S.) Retirement Communities CONFIDENTIAL Parexel 10
  • 11. Competition and Differentiation Product Manufacturer 2 Year Cost Buy (US$) Size Weight Lease (US$) GlowCaps Vitality 479 - NA NA PMD Philips 3127 4082 13” x 12” x 14” 12 lbs DAP Healthonemed 1190* 1764* 9.5” x 8” x 8.5” 10 lbs MD2 Medsmart 840 - 8 1/2” x 2 1/2” 793 gms 560 758 5” x 3” x 1” NA MedSignals Medsignals * Excluding monitoring expenses (needs company verification) Medistein’s Comparative Advantages Medistein’s Defensibility  Size (Form Factor)  Micro-force sensing technology to measure drug removal (patent pending #EP2013051084)  Setup / Installation  Strategic Relationship with FemtoTools AG (owner of the EPO patent #EP2013051084)  Compliance Management  Bespoke Software Apps  Drug Handling (Pills, Powder, Liquid)  Interoperability Bridge CONFIDENTIAL 11
  • 12. Team & Advisors Alok Narula Founder  Co-inventor, Portable Medication Unit (PMU)  Senior Staff Software Engineer, Broadcom Corp.  Senior Information Architect, Huawei Technologies Pvt. Ltd. Linkedin: Dr. Felix Beyeler Technical Advisor  Co-inventor, Portable Medication Unit (PMU)  CEO, FemtoTools AG, Switzerland Linkedin: JeetNath  President, Omnilink Technologies Inc., USA Technical Advisor Linkedin: CONFIDENTIAL 12
  • 13. Financial Projections S.No. Expense Year-I (US$)* Year-II (US$)* Year-III (US$)* 1 Office Space 120,000 120,000 180,000 2 Administration 50,000 70,000 100,000 3 Staff Salaries 1,500,000 2,000,000 3,000,000 4 IT Infrastructure 200,000 300,000 400,000 5 Lab Equipment 200,000 800,000 1,000,000 6 EDA Software 500,000 700,000 900,000 7 Prototyping 400,000 1,000,000 2,000,000 8 Regulatory (FDA) Testing 200,000 500,000 1,000,000 9 Patent Filing 300,000 500,000 500,000 10 Business Development 100,000 140,000 500,000 11 Sales & Marketing 100,000 200,000 500,000 3,670,000 6,330,000 10,080,000 Total * Estimates only CONFIDENTIAL 13
  • 14. Roadmap & Milestones Physical Integration System Integration Commercial Launch • Reference Board • Interoperability Bridge • Technology Partner Selection • Additional IP (Patent) • Final Prototype • Manufacturing Readiness • Vendor Selection • Additional IP (Patent) • Co-branding Partner Selection • Distribution Partner Selection • Marketing Partner Selection • Advertising Partner Selection Year 1 1-6 Months 5 Year Year 2 7-15 Months Year 0 16-24 Months Year 1 .. 2 25-48 Months Year 5 49-60 Months Year 2 .. 4 Product Definition Architecture Integration Regulatory Testing • IP (Patent) • Market Study • Micro-force Sensor • PMU Prototype • 1st Complete Prototype • Test Bench • Software Apps • Additional IP (Patent) • FDA / CE Compliance • Usability Testing • Package Selection • Service Partner Selection CONFIDENTIAL 14
  • 15. Capital & Returns Particulars Founder Contribution (Year 0) Amount (US$) 100,000 Activity  Patent (#EP2013051084, EPO Zurich)  Market Study  Micro-force Sensor Prototype Funds Required (Year 1-2) 10,000,000  1st Complete Prototype  Patents (10)  Software Apps  Test Bench  Interoperability Bridge Funds Required (Year 3) 10,000,000  GUI Prototype  Patents (5)  Product Prototype Package Prototype Funds Required (Year 4-5) Revenues (Year 5) Annual Revenues at full operations CONFIDENTIAL TBD 20,000,000 250,000,000  TBD  PMU Sales  App Sales  Rx Reorder Royalties  Co-branding Royalties  Mobile Value Added Services  From all the activities described in Year 5 15
  • 16. Exit Strategy Philips Healthcare Braun Medicals GECareinnovations Provides a compelling replacement to PMD. Provides Braun an Adds a new product to entry into Personal the Careinnovations Healthcare. product portfolio. Bosch Healthcare Adds a new product to the Bosch Healthcare product portfolio. Allows Philips to cross- Increases the sell the PMU to its brand value of existing customers. Braun Medicals through the #1 Compliance Device. Increases the brand value of GE Careinnovations through the #1 Medication Compliance Device. Increases the brand value of Bosch Healthcare through the #1 Medication Compliance Device. Provides interfaces to enhance the value and capabilities of the Philips health monitoring device (Telestation). Provides interfaces to enhance the value and capabilities of the GE health monitoring device (Health Guide). Provides interfaces to enhance the value and capabilities of the Bosch health monitoring device (Health Buddy). CONFIDENTIAL Provides a cheap alternative (via the IPad/Android S/W bridge) to build a health monitoring device. 16
  • 18. PMU Prototype App CONFIDENTIAL 18
  • 19. PMU Prototype Database CONFIDENTIAL 19
  • 20. References 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. OECD Factbook (OECD Database, 2011) Thinking Outside the Pillbox: A System-wide Approach to Improving Patient Medication Adherence for Chronic Disease (New England Healthcare Institute, August 2009) Seniorwatch 2: Assessment of the Senior Market for ICT Progress and Developments (European Commission, 2008) Responding to the Growing Cost and Prevalence of People With Multiple Chronic Conditions (John Hopkins Bloomberg School of Public Health, 2011) Cancer Survivorship Research (National Cancer Institute, 2011) Measuring cancer prevalence in Europe (The Europreval Project, 2002) OECD Health at a Glance (OECD Health Stats, 2011) Atlas of End Stage Renal Disease in the United States, (USRDS, 2011) Countrywide Statistics of End Stage Renal Disease (Rightdiagnosis, 2011) IDF Diabetes Atlas, 5th Edition, (IDF, 2012) Rational Use of Medicines (WHO, May 2010) Enhancing Prescription Medicine Adherence (National Council on Patient Information and Education, August 2007) Just what the Doctor Ordered: An EU Response to Medication Non-Adherence (Friends of Europe, 2010) CONFIDENTIAL 20