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Dengue
Dengue
Dengue
Dengue
Dengue
Dengue
Dengue
Dengue
Dengue
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Dengue

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  • 1. Enhancing surveillance for Dengue fever in Florida
  • 2. Dengue fever
    • Mosquito-borne viral disease
      • 4 serotypes (DEN 1,2,3,4)
      • Infection with one serotype confers immunity only to that serotype
      • Subsequent infection with another serotype increases risk of severe disease (dengue hemorrhagic fever/shock syndrome)
      • severe disease most common in children
  • 3. World Distribution of Aedes aegypti and Dengue - 1999 Areas infested with Aedes aegypti Areas with Aedes aegypti and dengue epidemic activity CDC Centers for Disease Control and Prevention
  • 4. Symptoms
    • Fever with 2 or more of:
      • headache
      • eye pain
      • muscle pain
      • joint pain
      • rash
      • hemorrhagic symptoms
  • 5. Why we care about dengue in Florida
    • Last epidemic: 1934-35
      • 15,000 cases in Miami (135,000 pop)
    • Indigenous transmission occurred in Texas in 1986 and 1995
    • The mosquito that transmits dengue is abundant in Florida
    • Dengue is endemic in Cuba, Mexico, and elsewhere in Caribbean, central and South America
  • 6. Enhanced dengue surveillance showed we have more cas es than we thought
    • 1987-96: mean of 1.3 cases per year reported in Florida
    • 1997-98: enhanced laboratory surveillance found 18 cases
    • All imported
    • Demonstrates potential for introduction of infection
    • We have the makings for endemic dengue in Florida
  • 7. Increasing surveillance in Florida
    • Tampa branch laboratory offers FREE dengue testing
    • Testing is more reliable than commercial labs
    • Provides state with faster results
    • Early detection earlier control efforts
  • 8. Requirements for testing
    • Serum (at least 1/2 ml)
    • Need acute and convalescent (3-4 weeks apart)
    • If you have CSF, send it: it can provide some additional information, but does not replace the two sera
    • Lab performs IgM and IgG ELISA tests
  • 9. Information required with samples
    • Person's name
    • Onset date
    • Symptoms
    • Travel history
    • Name of person to whom results should be send
    • Contact telephone numbers

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