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From questionable research practices
                to
     questions about research




 IMS Brown Bag Seminar   April 9th 2013   @TimSmitsTim
Why this seminar? Why me?
I am of a social psychological breed, so I feel a bit of a spotlight shining on
me, considering the recent fraud cases…
But also:

-I hate the spotlight on experimental lab studies

-I experienced a fair share of “too good to be true” moments

-Sometimes, I am just like a child when it comes to ethical standards and
then …
What is NOT at stake?
IN MY OPINION…

… it is not a problem of particular researchers. Frauds will always be
there but the major threat = dark-grey research practices

… it is not a problem of one single discipline (social psychology) or one
single research method (experimental research)
What is at stake?
Evolution of a whole lot of research disciplines depends on how we deal with
the situation right now.

-Singular fraud vs. systemic questionable practices?

And I fear the day this will inspire policy makers to cut down on our resources
(there is a crisis, you know) or business people deciding to design their own
educational system (or even worse, their own flawed research).
FRAUD    Diederik Stapel (50)
                                Data fabrication
                                Paper duplication
         Yoshitaka Fuji (183)
                                Plagiarism
         Dirk Smeesters
                                Lack of IRB approval

                                P-hacking
                                File drawer
                                One-sided lit. review
                                Biased content analysis
                                Biased interviews
         We?
         (communication
         sciences;
         KULeuven;              Other questionable
         IMS)                   research practices




THE POPE ; JESUS
Institutional and big-scheme
         interventions
-Retractions of flawed or fraudulent research papers; mega-corrections to
published articles

-Research on fraud and questionable research practices (and fierce
discussions among protagonists)

-Calls for replication studies; publication based on reviewed study design

-Open science networks: e.g. mere publication/replication depositories –
open science framework

-Post-publication review: Less intrusive than a letter to the editor; more open
access; closer to true academic discussion

-Judicial sanctions for busted researchers

-…
From retractionwatch.wordpress.com
YOUR interventions!!
-You ARE a scientist. So trust your feelings when they say “too good to be
true…”




An extreme example: Greg Francis’ research (though criticized by a.o. Uri
Simonsohn)

***For the following slides:
ALL CREDITS to Greg’s presentation on Febr 5th 2013 in Brussels***
Experimental methods
• Suppose you hear about two sets of experiments that investigate
  phenomena A and B
• Which effect is more believable?



                               Effect A           Effect B
        Number of
                                     10              19
        experiments
        Number of
        experiments that             9               10
        reject H0
        Replication rate          0.9               0.53
•   Effect A is Bem’s (2011) precognition study that reported evidence of
    people’s ability to get information from the future
     – I do not know any scientist who believes this effect is real
•   Effect B is from a meta-analysis of a version of the bystander effect, where
    people tend to not help someone in need if others are around
     – I do not know any scientist who does not believe this is a real effect
• So why are we running experiments?


                                  Effect A              Effect B
        Number of
                                      10                   19
        experiments
        Number of
        experiments that              9                    10
        reject H0
        Replication rate             0.9                  0.53
Hypothesis testing (for means)
• We start with a null hypothesis: no effect, H0
• Identify a sampling distribution that describes variability in a test
  statistic




    X1 - X 2
 t=
     sX -X
          1   2
Hypothesis testing (for two means)
•    We can identify rare test statistic values as those in the tail of the sampling distribution
•    If we get a test statistic in either tail, we say it is so rare (usually 0.05) that we should
     consider the null hypothesis to be unlikely
•    We reject the null




                                                       H0




       X1 - X 2
    t=
        sX -X
               1    2
Alternative hypothesis
• If the null hypothesis is not true, then the data came from some other
  sampling distribution (Ha)




                                        H0                    Ha
Power
•   If the alternative hypothesis is true
•   Power is the probability you will reject H0
•   If you repeated the experiment many times, you would expect to reject H0 with a
    proportion that reflects the power




                                               H0                        Ha
Power
• Use the pooled effect size to compute the pooled power of each
  experiment (probability this experiment would reject the null
  hypothesis)
                                                      Sample    Effect    Power
• Pooled effect                                        size    size (g)

  size                              Exp. 1             100      0.249     0.578
    – g*=0.1855                     Exp. 2             150      0.194     0.731
• The sum of the power              Exp. 3              97      0.248     0.567
                                    Exp. 4              99      0.202     0.575
values (E=6.27) is the
                                    Exp. 5             100      0.221     0.578
expected number of times            Exp. 6 Negative    150      0.146     0.731
these experiments would             Exp. 6 Erotic      150      0.144     0.731
                                    Exp. 7             200      0.092     0.834
reject the null hypothesis
                                    Exp. 8             100      0.191     0.578
   (Ioannidis & Trikalinos, 2007)
                                    Exp. 9              50      0.412     0.363
Take-home-message of Greg’s studies

-The file drawer phenomenon might be immense. Don’t put your money on
published studies
-Think not only about the p of your failed studies, but also their power.
-For most studies in our discipline, there is about a 50% chance to discover an
true phenomenon (since many studies are underpowered)
-Increase your N per hypothesis! It increases your “power” to discover an
effect (Ha= true) and (a bit) to refute an effect’s existence (H0= true)

Note:
To “detect” that men weigh more than women at an adequate power of .8,
you need to have n=46!!! (Simmons et al., 2013).
Are we studying effects that are stronger than men outweighing women??
-You ARE a scientist. So trust your feelings when they say “too good to be
true…”

-Engage in post-publication reviewing: do some active blogging about your
own studies; engage in discussions about others’ research

-Replicate! Or make others replicate. That is, investigate what others have
done already. Use all available data for your insights and do not take any
single study’s results for granted. Go ahead and p-hack your own data, but
replicate your own results

-Document your studies in a good way. Genuinely question yourself: is this
really everything one should need to know in order to replicate my study?

-Openness in reporting and reviewing. Be honest and confront reviewers if
they fetish immaculate papers

-Preferably, collaborate with other researchers and use shared repositories to
store data, analyses, notes, etc.
IRONICALLY,
the net result will be that more papers will be published rather than fewer, I
guess



Standards for what is good enough to be published, should go down. As a
result, more will be published, and meta-analysis will become the true
katalyst to scientific progress rather than single studies.

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IMS.BrownBagSeminar.QRP

  • 1. From questionable research practices to questions about research IMS Brown Bag Seminar April 9th 2013 @TimSmitsTim
  • 3. I am of a social psychological breed, so I feel a bit of a spotlight shining on me, considering the recent fraud cases…
  • 4.
  • 5. But also: -I hate the spotlight on experimental lab studies -I experienced a fair share of “too good to be true” moments -Sometimes, I am just like a child when it comes to ethical standards and then …
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  • 7. What is NOT at stake?
  • 8. IN MY OPINION… … it is not a problem of particular researchers. Frauds will always be there but the major threat = dark-grey research practices … it is not a problem of one single discipline (social psychology) or one single research method (experimental research)
  • 9. What is at stake?
  • 10. Evolution of a whole lot of research disciplines depends on how we deal with the situation right now. -Singular fraud vs. systemic questionable practices? And I fear the day this will inspire policy makers to cut down on our resources (there is a crisis, you know) or business people deciding to design their own educational system (or even worse, their own flawed research).
  • 11. FRAUD Diederik Stapel (50) Data fabrication Paper duplication Yoshitaka Fuji (183) Plagiarism Dirk Smeesters Lack of IRB approval P-hacking File drawer One-sided lit. review Biased content analysis Biased interviews We? (communication sciences; KULeuven; Other questionable IMS) research practices THE POPE ; JESUS
  • 13. -Retractions of flawed or fraudulent research papers; mega-corrections to published articles -Research on fraud and questionable research practices (and fierce discussions among protagonists) -Calls for replication studies; publication based on reviewed study design -Open science networks: e.g. mere publication/replication depositories – open science framework -Post-publication review: Less intrusive than a letter to the editor; more open access; closer to true academic discussion -Judicial sanctions for busted researchers -…
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  • 23. -You ARE a scientist. So trust your feelings when they say “too good to be true…” An extreme example: Greg Francis’ research (though criticized by a.o. Uri Simonsohn) ***For the following slides: ALL CREDITS to Greg’s presentation on Febr 5th 2013 in Brussels***
  • 24. Experimental methods • Suppose you hear about two sets of experiments that investigate phenomena A and B • Which effect is more believable? Effect A Effect B Number of 10 19 experiments Number of experiments that 9 10 reject H0 Replication rate 0.9 0.53
  • 25. Effect A is Bem’s (2011) precognition study that reported evidence of people’s ability to get information from the future – I do not know any scientist who believes this effect is real • Effect B is from a meta-analysis of a version of the bystander effect, where people tend to not help someone in need if others are around – I do not know any scientist who does not believe this is a real effect • So why are we running experiments? Effect A Effect B Number of 10 19 experiments Number of experiments that 9 10 reject H0 Replication rate 0.9 0.53
  • 26. Hypothesis testing (for means) • We start with a null hypothesis: no effect, H0 • Identify a sampling distribution that describes variability in a test statistic X1 - X 2 t= sX -X 1 2
  • 27. Hypothesis testing (for two means) • We can identify rare test statistic values as those in the tail of the sampling distribution • If we get a test statistic in either tail, we say it is so rare (usually 0.05) that we should consider the null hypothesis to be unlikely • We reject the null H0 X1 - X 2 t= sX -X 1 2
  • 28. Alternative hypothesis • If the null hypothesis is not true, then the data came from some other sampling distribution (Ha) H0 Ha
  • 29. Power • If the alternative hypothesis is true • Power is the probability you will reject H0 • If you repeated the experiment many times, you would expect to reject H0 with a proportion that reflects the power H0 Ha
  • 30. Power • Use the pooled effect size to compute the pooled power of each experiment (probability this experiment would reject the null hypothesis) Sample Effect Power • Pooled effect size size (g) size Exp. 1 100 0.249 0.578 – g*=0.1855 Exp. 2 150 0.194 0.731 • The sum of the power Exp. 3 97 0.248 0.567 Exp. 4 99 0.202 0.575 values (E=6.27) is the Exp. 5 100 0.221 0.578 expected number of times Exp. 6 Negative 150 0.146 0.731 these experiments would Exp. 6 Erotic 150 0.144 0.731 Exp. 7 200 0.092 0.834 reject the null hypothesis Exp. 8 100 0.191 0.578 (Ioannidis & Trikalinos, 2007) Exp. 9 50 0.412 0.363
  • 31. Take-home-message of Greg’s studies -The file drawer phenomenon might be immense. Don’t put your money on published studies -Think not only about the p of your failed studies, but also their power. -For most studies in our discipline, there is about a 50% chance to discover an true phenomenon (since many studies are underpowered) -Increase your N per hypothesis! It increases your “power” to discover an effect (Ha= true) and (a bit) to refute an effect’s existence (H0= true) Note: To “detect” that men weigh more than women at an adequate power of .8, you need to have n=46!!! (Simmons et al., 2013). Are we studying effects that are stronger than men outweighing women??
  • 32. -You ARE a scientist. So trust your feelings when they say “too good to be true…” -Engage in post-publication reviewing: do some active blogging about your own studies; engage in discussions about others’ research -Replicate! Or make others replicate. That is, investigate what others have done already. Use all available data for your insights and do not take any single study’s results for granted. Go ahead and p-hack your own data, but replicate your own results -Document your studies in a good way. Genuinely question yourself: is this really everything one should need to know in order to replicate my study? -Openness in reporting and reviewing. Be honest and confront reviewers if they fetish immaculate papers -Preferably, collaborate with other researchers and use shared repositories to store data, analyses, notes, etc.
  • 33. IRONICALLY, the net result will be that more papers will be published rather than fewer, I guess Standards for what is good enough to be published, should go down. As a result, more will be published, and meta-analysis will become the true katalyst to scientific progress rather than single studies.