Proton therapy

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Proton therapy

  1. 1. AN ADVANCED TECHNOLOGY IN TREATMENT OF CANCERS
  2. 2. Introduction Proton therapy is a form of particle therapy which uses a beam of protons to irradiate diseased tissue, most often in the treatment of cancer. The chief advantage of proton therapy is the ability to more precisely localize the radiation dosage when compared with other types of external beam radiotherapy.
  3. 3. Description The accelerators used for proton therapy typically produce protons with energies in the range of 70 to 250 MeV . Such protons cause DNA damage specifically to the cells of the selected area without affecting the nearby tissue. The dose delivered to tissue is maximum just over the last few millimeters of the particle’s range; this maximum is called the Bragg peak. All protons of a given energy have a certain range, very few protons penetrate beyond that distance.
  4. 4. Depth-dose plot of proton and x-ray beam
  5. 5. COMPOSITION OF PROTONACCELERATOR
  6. 6. Advantages1. Most precise form of radiation treatment available today.2. Is non-invasive and painless.3. Avoids the usual side effects of standard x-ray radiation.4. Highly preferred radiation treatment modality option for pediatric cases because children are susceptible to injury from standard x-ray radiation .
  7. 7. Side effects and risks Preliminary results from a 2009 study, including high dose treatments, show very few or no side effects.
  8. 8. Applications Conditions Treated  Prostate,  Base of Skull,  Brain and Spinal Cord,  Eye,  Head and Neck,  Chest and Abdomen,  Tumors in Children.
  9. 9. Comparison with other treatmentoptions X-ray radiotherapy X-ray radiation dose falls off gradually, while tissues deeper in the body than the tumor receive essentially no radiation during proton therapy. X-ray therapy causes damage to the tumor as well as the surrounding healthy tissues. .
  10. 10.  Surgery The benefit of external beam proton radiation lies in the dosimetric difference from external beam x-ray radiation and brachytherapy in cases, where the use of radiation therapy is already indicated, rather than as a direct competition with surgery.
  11. 11. THANKS FORATTENTION M. Deyab CELL BIOLOGY

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