==== ====Get free e-books on a variety of topics from Affiliate Marketing to how to heal with crystals.http://thothknows.blogspot.com/==== ====The list of possible alpha lipoic acid benefits is long, while negative side effects are rare.There have been numerous alpha lipoic acid clinical studies, pre clinical trials and laboratorystudies. This is merely a brief review of those studies.First, just to be clear, here is a brief explanation of the difference between clinical and pre clinicalstudies. Alpha lipoic acid clinical studies are those which include real people with or withoutspecific health conditions in a controlled setting.Other studies are considered pre clinical, because they took place in a laboratory setting usingeither cell lines or animal models.When results of pre clinical trials are promising, researchers typically recommend that clinicalstudies should be performed.In the case of small alpha lipoic acid clinical studies or single blind studies, researchers usuallysuggest larger more controlled studies. The alpha lipoic acid clinical studies that are consideredmost scientifically sound are those that are placebo controlled and double blind.A placebo controlled study is one in which about half of the participants receive an activesubstance and about half receive an inactive substance or "placebo". Double blinding means thatneither the person receiving the substance, nor the person "handing out the pills" knows which is"real" and which is not.Double blind placebo controlled studies are particularly important when evaluating symptoms suchas pain relief, but not so much in other cases. And in some cases clinical studies are simplyimpossible.For example, alpha lipoic acid benefits that have been suggested by laboratory studies include theprevention of cancer. There is no way to use clinical studies to prove this theory, but in thelaboratory, it has been shown that ALA prevents the growth of cancerous cell lines and tumors.Alpha lipoic acid clinical studies have shown benefit to patients who have undergone radiationand/or chemotherapy for the treatment of cancer.Other laboratory studies have indicated that alpha lipoic acid benefits may include the preventionof heart disease. With this in mind, researchers at Boston University School of Medicineconducted a double blind placebo controlled study lasting eight weeks.
In their opening statement researchers pointed out that ALA and l-carnitine are known to reduceoxidative stress and improve mitochondrial function. Their goal was to see what if any effectsupplementation would have on patients with coronary artery disease, high blood pressure andmetabolic syndrome.Study participants were patients with either coronary artery disease or metabolic syndrome. At theend of the eight week trial, those participants receiving ALA and acetyl-l-carnitine had significantlylower blood pressure and increased diameter in the brachial artery, the major blood vessel in thearm.This study suggests that alpha lipoic acid benefits include stabilizing blood pressure and improvingblood flow and support the idea that ALA supplements may help prevent heart disease.Many alpha lipoic acid clinical studies have focused on the benefits to people suffering fromdiabetes, in particular those people whose small blood vessels have been damaged by high levelsof glucose in the blood stream for an extended period of time, a condition called diabetic distalsymmetric polyneuropathy or diabetic neuropathy.Researchers at the Mayo Clinic reported that ALA at 600mg/day relieved the pain associated withthis condition. Numerous alpha lipoic acid clinical studies from around the world support thisconclusion.At the Department of Neuroscience in Pisa, Italy ALA has been used along with vitamin E,coenzyme Q10, riboflavin, creatine and exercise training to effectively treat mitochondrialdiseases, a group of disorders caused by damage to the DNA of the mitochondria. Themitochondria are the powerhouses of the cells of the human body, responsible for converting foodmolecules into the energy that fuels cellular functions.Other studies suggest that ALA may protect mitochondria from the damage that occurs during theaging process, although these are laboratory studies, not alpha lipoic acid clinical studies.One of the small alpha lipoic acid clinical studies concluded that alpha lipoic acid benefits mayinclude the relief of migraines. Clinicians at the Headache Research Unit in Belgium evaluated thesymptoms of nearly 100 migraine sufferers over a period of three months. This was a single blindplacebo controlled study, so results need to be followed up with a larger clinical trial.But, these researchers found that the frequency and severity of migraine attacks were less inparticipants receiving ALA, while participants receiving placebo reported no change at all. Thesescientists described ALA in this way "known to enhance energy metabolism in mitochondria and tobe beneficial in diabetic neuropathy".According to the Alternative Medicine Review, alpha lipoic acid benefits to human health were firstidentified in the 1980s. Researchers and scientists accept the fact that ALA is a powerfulantioxidant that neutralizes free radicals in both the fatty and watery regions of cells. Otherantioxidants work in either the watery regions (vitamin C) or the fatty regions (vitamin E) but notboth.Over the years, alpha lipoic acid clinical studies have shown that the supplement can be used to
treat and prevent deficiencies in vitamin C or E. With this and other evidence, it can be stated withconfidence that alpha lipoic acid benefits and enhances the performance of other antioxidants.Other alpha lipoic acid benefits listed by the Alternative Medicine Review include the treatment ofglaucoma and heavy metal poisoning. Supplements may be beneficial to stroke victims and topersons who have suffered from a clot in the arteries of the heart.Many sources state that it may be helpful in the prevention and treatment of Alzheimers andParkinsons. Laboratory studies have shown that it prevents the replication of the HIV virus.Several alpha lipoic acid clinical studies have shown benefit to persons suffering from BurningMouth Syndrome.People with type II diabetes, pre-diabetes, insulin resistance or a family history of type II diabetesshould know that ALA enhances insulin sensitivity and stimulates the production of insulin.Although this means that the possible prevention of type II diabetes is one of the many alpha lipoicacid benefits, it also means that it should be used with caution by persons with hypoglycemia, lowblood sugar or a tendency towards hypoglycemic. Although actual hypoglycemia is rare, it is justas life threatening as hyperglycemia.It may seem that alpha lipoic acid helps practically every system and every part of the human bodyand this is actually true, because mitochondria exist in every cell and alpha lipoic acid benefits tomitochondria are well established and accepted by the scientific community.Mila Sabido is editor of http://www.nutritional-supplements-information.com . Visithttp://www.nutritional-supplements-information.com/alpha-lipoic-acid-benefits.html for more info onhow to choose a quality supplement containing alpha lipoic acid.Article Source:http://EzineArticles.com/?expert=Mila_Sabido==== ====Get free e-books on a variety of topics from Affiliate Marketing to how to heal with crystals.http://thothknows.blogspot.com/==== ====