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Rifagut Tablets for Treatment of Travelers' Diarrhea & Hepatic Encephalopathy
 

Rifagut Tablets for Treatment of Travelers' Diarrhea & Hepatic Encephalopathy

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Rifagut Tablets (Rifaximin) is an antibacterial used for the treatment of travelers diarrhea (TD). It is also used for reduction in risk of overt hepatic encephalopathy (HE) recurrence in ...

Rifagut Tablets (Rifaximin) is an antibacterial used for the treatment of travelers diarrhea (TD). It is also used for reduction in risk of overt hepatic encephalopathy (HE) recurrence in patients.

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    Rifagut Tablets for Treatment of Travelers' Diarrhea & Hepatic Encephalopathy Rifagut Tablets for Treatment of Travelers' Diarrhea & Hepatic Encephalopathy Presentation Transcript

    • Rifagut Tablets Rifagut is an antibacterial used for the treatment of travelers diarrhea (TD) caused by noninvasive strains of Escherichia coli in patients 12 years of age and older. It is also used for reduction in risk of overt hepatic encephalopathy (HE) recurrence in patients 18 years of age and older. The active ingedient present in Rifagut is Rifaximin.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Indications Rifagut Tablets is an antibacterial. Rifagut Tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Rifagut 200 mg is indicated for the treatment of travelers diarrhea (TD) caused by non- invasive strains of Escherichia coli in patients 12 years of age and older.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Indications Rifagut Tablets (Rifaximin) should not be used in patients with diarrhea complicated by fever or blood in the stool or diarrhea due to pathogens other than Escherichia coli. It is also used for reduction in risk of overt hepatic encephalopathy (HE) recurrence in patients 18 years of age and older.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Active Ingredient The active pharmaceutical ingredient contained in Rifagut Tablets is Rifaximin. Rifaximin is a semisynthetic antibiotic based on Rifamycin.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Chemical Structure© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Recommended Dosage The recommended dosage of Rifaximin for thetreatment of various indications is given below:➔Travelers’ Diarrhea: The recommended dose ofRifagut is one 200 mg tablet taken orally threetimes a day for 3 days. Rifagut can be administeredorally, with or without food.➔Hepatic Encephalopathy: The recommendeddose of Rifagut (Rifaximin) is one 550 mg tablettaken orally two times a day, with or without food.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets ContraindicationsRifagut (Rifaximin Tablets) is contraindicatedin patients with the following conditions:➔Hypersensitivity to Rifaximin, or any inactivecomponent of this medication.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Side Effects of Rifagut TabletsThe most common side effects of of RifagutTablets in the treatment of Travelers’ Diarrheawith an incidence rate of 5% or more Flatulence,headache, abdominal pain, rectal tenesmus,defecation urgency and nausea.Most common side effects of Rifaximin (RifagutTablets) in the treatment of HepaticEncephalopathy with an incidence rate of 10%or more are Peripheral edema, nausea,dizziness, fatigue, ascites, flatulence, andheadache.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Warnings And Precautions ➔ Travelers Diarrhea Not Caused by Escherichia coli: Rifagut was not found to be effective in patients with diarrhea complicated by fever and/or blood in the stool or diarrhea due to pathogens other than Escherichia coli. Rifagut has to be discontinued if diarrhea symptoms get worse or persist for more than 24 to 48 hours and alternative antibiotic therapy should be considered. ➔Rifagut is not effective in cases of travelers’ diarrhea due to Campylobacter jejuni. The effectiveness of Rifagut in travelers’ diarrhea caused by Shigella spp. and Salmonella spp. has not been proven. Rifagut should not be used in patients where Campylobacter jejuni, Shigella spp., or Salmonella spp. may be suspected as causative pathogens.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Warnings And Precautions ➔ Clostridium difficile-Associated Diarrhea: Clostridium difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including Rifagut, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon which may lead to overgrowth of C. difficile. ➔Development of Drug Resistant Bacteria: Prescribing Rifagut for travelers’ diarrhea in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Warnings And Precautions ➔Severe (Child-Pugh C) Hepatic Impairment: There is increased systemic exposure in patients with severe hepatic impairment. Therefore, caution should be exercised when administering Rifaximin (Rifagut Tablets) to patients with severe hepatic impairment (Child-Pugh C).© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Overdose SymptomsNo specific information is available on the treatmentof overdosage with Rifaximin (Rifagut Tablets). Inclinical studies at doses higher than therecommended dose (more than 600 mg/day fortravelers’ diarrhea or more than 1100 mg/day forhepatic encephalopathy), adverse reactions weresimilar in patients who received doses higher thanthe recommended dose and placebo.In the case of overdosage, discontinue Rifaximin,treat symptomatically, and institute supportivemeasures as required.© The Swiss Pharmacy, Geneva Switzerland
    • Rifagut Tablets Rifagut Tablets from Sun Pharmaceutical Industries Ltd., India For more information click here© The Swiss Pharmacy, Geneva Switzerland