Micronized Progesterone Capsules 
Micronized Progesterone Soft Gelatin Capsules 
(Endogest 100 mg and 200 mg) are used in ...
Micronized Progesterone Capsules 
Chemical Structure 
© The Swiss Pharmacy, Geneva Switzerland
Micronized Progesterone Capsules 
Active Ingredient 
The active pharmaceutical ingredient 
contained in Endogest Soft Gela...
Micronized Progesterone Capsules 
Recommended Adult Dosage 
The recommended dosage of Micronized 
Progesterone capsules (E...
Micronized Progesterone Capsules 
Contraindications 
Micronized Progesterone Soft Gelatin 
Capsules (Endogest 100 mg and 2...
Micronized Progesterone Capsules 
Contraindications 
Micronized Progesterone Soft Gelatin 
Capsules (Endogest 100 mg and 2...
Micronized Progesterone Capsules 
Side Effects of Micronized Progesterone 
The most common side effects of Micronized 
Pro...
Micronized Progesterone Capsules 
Warnings And Precautions 
➔Should Thrombotic disorders (thrombophlebitis, 
cerebrovascul...
Micronized Progesterone Capsules 
Warnings And Precautions 
➔Since Progesterone may cause some degree of fluid 
retention,...
Micronized Progesterone Capsules 
Overdose Symptoms 
The toxicity of Progesterone is very low. 
In case of overdose of End...
Micronized Progesterone Capsules 
Overdose Treatment 
In the case of overdosage, treatment 
with Endogest Soft Gelatin Cap...
Micronized Progesterone Capsules 
Endogest 100 mg & 200 mg Capsules 
manufactured by Cipla Ltd., India 
For more informati...
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Micronized Progesterone Capsules for Prevention of Endometrial Hyperplasia & to Maintain Pregnancy

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Micronized Progesterone Soft Gelatin Capsules (Endogest 100 mg and 200 mg) are used in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also used to treat secondary amenorrhea as well as to maintain pregnancy.

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Micronized Progesterone Capsules for Prevention of Endometrial Hyperplasia & to Maintain Pregnancy

  1. 1. Micronized Progesterone Capsules Micronized Progesterone Soft Gelatin Capsules (Endogest 100 mg and 200 mg) are used in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also used to treat secondary amenorrhea as well as to maintain pregnancy. © The Swiss Pharmacy, Geneva Switzerland
  2. 2. Micronized Progesterone Capsules Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  3. 3. Micronized Progesterone Capsules Active Ingredient The active pharmaceutical ingredient contained in Endogest Soft Gelatin Capsules is Micronized Progesterone. Each 100 mg capsule contains 100 mg of the active ingredient Micronized Progesterone. © The Swiss Pharmacy, Geneva Switzerland
  4. 4. Micronized Progesterone Capsules Recommended Adult Dosage The recommended dosage of Micronized Progesterone capsules (Endogest) is given below: ➔Prevention of Endometrial Hyperplasia: Micronized Progesterone capsules should be given as a single daily dose in the evening, 200 mg orally for 12 days sequentially per 28 day cycle, to postmenopausal women with a uterus who are receiving daily conjugated estrogens tablets. ➔Secondary Amenorrhea: Micronized Progesterone Capsules may be given as a single daily dose of 400 mg in the evening for 10 days. © The Swiss Pharmacy, Geneva Switzerland
  5. 5. Micronized Progesterone Capsules Contraindications Micronized Progesterone Soft Gelatin Capsules (Endogest 100 mg and 200 mg) are contraindicated in patients with the following conditions: ➔Known hypersensitivity to Progesterone or any inactive ingredient of this medication. ➔Thrombophlebitis, thromboembolic disorders, cerebral apoplexy, or patients with a past history of these conditions. ➔Severe liver dysfunction or disease. ➔Known or suspected malignancy of breast or genital organs. © The Swiss Pharmacy, Geneva Switzerland
  6. 6. Micronized Progesterone Capsules Contraindications Micronized Progesterone Soft Gelatin Capsules (Endogest 100 mg and 200 mg) are contraindicated in patients with the following conditions: ➔Undiagnosed vaginal bleeding. ➔Missed abortion. ➔As a diagnostic test for pregnancy. © The Swiss Pharmacy, Geneva Switzerland
  7. 7. Micronized Progesterone Capsules Side Effects of Micronized Progesterone The most common side effects of Micronized Progesterone capsules (Endogest) are Headache, Breast Tenderness, Joint Pain, Depression, Dizziness, Abdominal Bloating, Hot Flashes, Urinary Problems, Abdominal Pain, Vaginal Discharge, Nausea / Vomiting, Worry, Chest Pain, Diarrhea, Night Sweats, Breast Pain, Swelling of Hands and Feet, Vaginal Dryness, Constipation, Breast Carcinoma, Breast Excisional Biopsy and Cholecystectomy. © The Swiss Pharmacy, Geneva Switzerland
  8. 8. Micronized Progesterone Capsules Warnings And Precautions ➔Should Thrombotic disorders (thrombophlebitis, cerebrovascular disorders, pulmonary embolism, and retinal thrombosis) occur or be suspected, Micronized Progesterone capsules should be discontinued immediately. ➔Discontinue medication pending examination if there is sudden partial or complete loss of vision, or if there is a sudden onset of proptosis, diplopia or migraine. If examination reveals papilledema or retinal vascular lesions, medication should be withdrawn. ➔Pretreatment physical examination should include special reference to breast and pelvic organs, as well as Papanicolaou smear. © The Swiss Pharmacy, Geneva Switzerland
  9. 9. Micronized Progesterone Capsules Warnings And Precautions ➔Since Progesterone may cause some degree of fluid retention, conditions which might be influenced by this factor, such as epilepsy, migraine, asthma, cardiac or renal dysfunction, require careful observation. ➔In cases of breakthrough bleeding, as in any cases of irregular bleeding per vaginum, nonfunctional causes should be borne in mind. ➔Patients who have a history of psychic depression should be carefully observed and the drug discontinued if the depression recurs to a serious degree. ➔Transient dizziness may occur in some patients. Use caution when driving a motor vehicle or operating machinery. © The Swiss Pharmacy, Geneva Switzerland
  10. 10. Micronized Progesterone Capsules Overdose Symptoms The toxicity of Progesterone is very low. In case of overdose of Endogest Soft Gelatin Capsules (Micronized Progesterone), the following symptoms may arise: nausea, vomiting, sleepiness, dizziness, depressive mood, tiredness, acne and hirsutism (hairiness). © The Swiss Pharmacy, Geneva Switzerland
  11. 11. Micronized Progesterone Capsules Overdose Treatment In the case of overdosage, treatment with Endogest Soft Gelatin Capsules (Micronized Progesterone), should be discontinued and the patient should be treated symptomatically. © The Swiss Pharmacy, Geneva Switzerland
  12. 12. Micronized Progesterone Capsules Endogest 100 mg & 200 mg Capsules manufactured by Cipla Ltd., India For more information click here © The Swiss Pharmacy, Geneva Switzerland
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