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Generic Wellbutrin Tablets 
Generic Wellbutrin Tablets (Bupron) is 
used for the treatment of Major Depressive 
Disorder. ...
Generic Wellbutrin Tablets 
Active Ingredient 
The active pharmaceutical ingredient 
contained in Generic Wellbutrin Table...
Generic Wellbutrin Tablets 
Chemical Structure 
© The Swiss Pharmacy, Geneva Switzerland
Generic Wellbutrin Tablets 
Recommended Dosage 
Usual Dosage for Adults: 
The usual adult dose of Generic Wellbutrin table...
Generic Wellbutrin Tablets 
Contraindications 
Bupron (Generic Wellbutrin Tablets) is 
contraindicated in patients with th...
Generic Wellbutrin Tablets 
Contraindications 
Generic Wellbutrin Tablets (Bupron) is 
contraindicated in patients with th...
Generic Wellbutrin Tablets 
Side Effects of Generic Wellbutrin 
The most common side effects are agitation, 
dry mouth, in...
Generic Wellbutrin Tablets 
Warnings And Precautions 
➔Clinical Worsening and Suicide Risk in Treating 
Psychiatric Disord...
Generic Wellbutrin Tablets 
Warnings And Precautions 
➔Hepatic Impairment: Bupron tablets (Generic Wellbutrin) 
should be ...
Generic Wellbutrin Tablets 
Warnings And Precautions 
➔Activation of Psychosis and/or Mania: Antidepressants 
can precipit...
Generic Wellbutrin Tablets 
Warnings And Precautions 
➔Allergic Reactions: Anaphylactoid/anaphylactic 
reactions character...
Generic Wellbutrin Tablets 
Warnings And Precautions 
➔Hepatic Impairment: Bupron tablets (Generic 
Wellbutrin) should be ...
Generic Wellbutrin Tablets 
Overdose Symptoms 
Overdoses of up to 30 g or more of Bupropion 
(Generic Wellbutrin) have bee...
Generic Wellbutrin Tablets 
Overdose Treatment 
Patients should be managed by general 
supportive and symptomatic measures...
Generic Wellbutrin Tablets 
Bupron Tablets (Generic Wellbutrin) 
from Sun Pharmaceuticals Ltd., India. 
For more informati...
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Generic Wellbutrin Tablets for the Treatment of Major Depressive Disorder

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Generic Wellbutrin Tablets (Bupron) is used for the treatment of Major Depressive Disorder. It is also used to treat Seasonal Affective Disorder (SAD).

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Transcript of "Generic Wellbutrin Tablets for the Treatment of Major Depressive Disorder"

  1. 1. Generic Wellbutrin Tablets Generic Wellbutrin Tablets (Bupron) is used for the treatment of Major Depressive Disorder. It is also used to treat Seasonal Affective Disorder (SAD) which are episodes of depression that occur in the fall and winter each year. © The Swiss Pharmacy, Geneva Switzerland
  2. 2. Generic Wellbutrin Tablets Active Ingredient The active pharmaceutical ingredient contained in Generic Wellbutrin Tablets is Bupropion Hydrochloride. Each 150 mg Bupron tablet contains 150 mg of Bupropion Hydrochloride. © The Swiss Pharmacy, Geneva Switzerland
  3. 3. Generic Wellbutrin Tablets Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  4. 4. Generic Wellbutrin Tablets Recommended Dosage Usual Dosage for Adults: The usual adult dose of Generic Wellbutrin tablets (Bupron tablets) is 300 mg/day, given 3 times daily. Dosing should begin at 200 mg/day, given as 100 mg twice daily. Based on clinical response, this dose may be increased to 300 mg/day, given as 100 mg 3 times daily, not earlier than 3 days after starting therapy. © The Swiss Pharmacy, Geneva Switzerland
  5. 5. Generic Wellbutrin Tablets Contraindications Bupron (Generic Wellbutrin Tablets) is contraindicated in patients with the following conditions: ➔Hypersensitivity to Bupropion Hydrochloride, or any inactive component of this medication. ➔In patients treated with Generic Wellbutrin tablets or any other medications that contain Bupropion. ➔In patients with a current or prior diagnosis of Bulimia or Anorexia Nervosa. ➔In patients undergoing abrupt discontinuation of alcohol or sedatives (including benzodiazepines) © The Swiss Pharmacy, Geneva Switzerland
  6. 6. Generic Wellbutrin Tablets Contraindications Generic Wellbutrin Tablets (Bupron) is contraindicated in patients with the following conditions: ➔Use of monoamine oxidase inhibitors or MAOIs (intended to treat psychiatric disorders) concomitantly with Bupron (Generic Wellbutrin Tablets) or within 14 days of stopping treatment with Bupron is contraindicated. © The Swiss Pharmacy, Geneva Switzerland
  7. 7. Generic Wellbutrin Tablets Side Effects of Generic Wellbutrin The most common side effects are agitation, dry mouth, insomnia, headache/migraine, nausea/vomiting, constipation, and tremor. The more common Side effects causing discontinuation include neuropsychiatric disturbances (3.0%), primarily agitation and abnormalities in mental status; gastrointestinal disturbances (2.1%), primarily nausea and vomiting; neurological disturbances (1.7%), primarily seizures, headaches, and sleep disturbances; and dermatologic problems (1.4%), primarily rashes. © The Swiss Pharmacy, Geneva Switzerland
  8. 8. Generic Wellbutrin Tablets Warnings And Precautions ➔Clinical Worsening and Suicide Risk in Treating Psychiatric Disorders: Patients with Major Depressive Disorder (MDD), may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, until significant remission occurs. ➔Seizures:Bupropion is associated with seizures in approximately 0.4% (4/1,000) of patients treated at doses up to 450 mg/day. The risk of seizure is also related to patient factors, clinical situations, and concomitant medications. © The Swiss Pharmacy, Geneva Switzerland
  9. 9. Generic Wellbutrin Tablets Warnings And Precautions ➔Hepatic Impairment: Bupron tablets (Generic Wellbutrin) should be used with extreme caution in patients with severe hepatic cirrhosis. ➔Agitation and Insomnia: A substantial proportion of patients treated with Generic Wellbutrin Tablets (Bupron) experience some degree of increased restlessness, agitation, anxiety, and insomnia, especially shortly after initiation of treatment. ➔Psychosis, Confusion, and Other Neuropsychiatric Phenomena: Depressed patients treated with Generic Wellbutrin (Bupron Tablets) have been reported to show a variety of neuropsychiatric signs and symptoms including delusions, hallucinations, psychosis, concentration disturbance, paranoia, and confusion. © The Swiss Pharmacy, Geneva Switzerland
  10. 10. Generic Wellbutrin Tablets Warnings And Precautions ➔Activation of Psychosis and/or Mania: Antidepressants can precipitate manic episodes in bipolar disorder patients during the depressed phase of their illness and may activate latent psychosis in other susceptible patients. Generic Bupropion is expected to pose similar risks. ➔Altered Appetite and Weight: A weight loss of greater than 5 lbs occurred in 28% of patients receiving Generic Bupropion. ➔Cardiovascular Effects: In clinical practice, hypertension, sometimes severe, requiring acute treatment, has been reported in patients receiving Bupropion (Generic Wellbutrin) alone and in combination with nicotine replacement therapy. © The Swiss Pharmacy, Geneva Switzerland
  11. 11. Generic Wellbutrin Tablets Warnings And Precautions ➔Allergic Reactions: Anaphylactoid/anaphylactic reactions characterized by symptoms such as pruritus, urticaria, angioedema, and dyspnea requiring medical treatment have been reported in clinical trials with Bupropion. In addition, there have been rare spontaneous postmarketing reports of erythema multiforme, Stevens- Johnson syndrome, and anaphylactic shock associated with Bupropion. A patient should stop taking Generic Bupropion and consult a doctor if experiencing allergic or anaphylactoid/anaphylactic reactions (e.g., skin rash, pruritus, hives, chest pain, edema, and shortness of breath) during treatment. Arthralgia, myalgia, and fever with rash and other symptoms suggestive of delayed hypersensitivity have been reported in association with Generic Wellbutrin (Bupron Tablets). © The Swiss Pharmacy, Geneva Switzerland
  12. 12. Generic Wellbutrin Tablets Warnings And Precautions ➔Hepatic Impairment: Bupron tablets (Generic Wellbutrin) should be used with extreme caution in patients with severe hepatic cirrhosis. In these patients, a reduced dose and frequency is required. ➔Renal Impairment: Bupron tablets (Generic Wellbutrin) should be used with caution in patients with renal impairment and a reduced frequency and/or dose should be considered as bupropion and the metabolites of bupropion may accumulate in such patients to a greater extent than usual. © The Swiss Pharmacy, Geneva Switzerland
  13. 13. Generic Wellbutrin Tablets Overdose Symptoms Overdoses of up to 30 g or more of Bupropion (Generic Wellbutrin) have been reported. Seizure was reported in approximately one-third of all cases. Other serious reactions reported with overdoses of bupropion alone included hallucinations, loss of consciousness, sinus tachycardia, and ECG changes such as conduction disturbances (including QRS prolongation) or arrhythmias. Fever, muscle rigidity, rhabdomyolysis, hypotension, stupor, coma, and respiratory failure have been reported mainly when Bupropion was part of multiple drug overdoses. © The Swiss Pharmacy, Geneva Switzerland
  14. 14. Generic Wellbutrin Tablets Overdose Treatment Patients should be managed by general supportive and symptomatic measures following overdose. There are no specific antidotes for Generic Wellbutrin (Bupropion). Ensure an adequate airway, oxygenation, and ventilation. Monitor cardiac rhythm and vital signs. EEG monitoring is also recommended for the first 48 hours post-ingestion. Activated charcoal should be administered. Induction of emesis is not recommended. © The Swiss Pharmacy, Geneva Switzerland
  15. 15. Generic Wellbutrin Tablets Bupron Tablets (Generic Wellbutrin) from Sun Pharmaceuticals Ltd., India. For more information click here © The Swiss Pharmacy, Geneva Switzerland
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