Generic Tegretol Tablets for treatment of Epileptic Seizures and Trigeminal Neuralgia

1,359
-1

Published on

Generic Tegretol (Zeptol Tablets) is used for treating certain types of epileptic seizures and treats severe pain of the jaw or cheek caused by a facial nerve problem (trigeminal neuralgia).

0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
1,359
On Slideshare
0
From Embeds
0
Number of Embeds
29
Actions
Shares
0
Downloads
4
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide

Generic Tegretol Tablets for treatment of Epileptic Seizures and Trigeminal Neuralgia

  1. 1. Generic Tegretol Tablets Generic Tegretol (Zeptol Tablets) is used for controlling Partial seizures with complex symptomatology, Generalized tonic-clonic seizures (grand mal) and Mixed seizure patterns which include the above, or other partial or generalized seizures (Epileptic Seizures). Generic Tegretol is also used in the treatment of the pain associated with true trigeminal neuralgia (facial nerve problem). © The Swiss Pharmacy, Geneva Switzerland
  2. 2. Generic Tegretol Tablets Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  3. 3. Generic Tegretol Tablets Active Ingredient The active pharmaceutical ingredient contained in Generic Tegretol Tablets is Carbamazepine. Each 200 mg Tegretol tablet contains 200 mg of Carbamazepine. © The Swiss Pharmacy, Geneva Switzerland
  4. 4. Generic Tegretol Tablets Recommended Dosage Epilepsy: Adults and children over 12 years of age: Initial: 200 mg twice a day. Increase at weekly intervals by adding up to 200 mg/day using a twice a day regimen until the optimal response is obtained. Dosage generally should not exceed 1000 mg daily in children 12-15 years of age, and 1200 mg daily in patients above 15 years of age. Maintenance: Adjust dosage to the minimum effective level, usually 800-1200 mg daily. © The Swiss Pharmacy, Geneva Switzerland
  5. 5. Generic Tegretol Tablets Recommended Dosage Epilepsy Children 6-12 years of age: Initial:100 mg twice a day. Increase at weekly intervals by adding up to 100 mg/day using a twice a day regimen until the optimal response is obtained. Dosage generally should not exceed 1000 mg daily Maintenance: Adjust dosage to the minimum effective level, usually 400-800 mg daily. © The Swiss Pharmacy, Geneva Switzerland
  6. 6. Generic Tegretol Tablets Recommended Dosage Epilepsy Children under 6 years of age: Initial: 10-20 mg/kg/day twice a day. Increase weekly to achieve optimal clinical response administered thrice a day or four times a day. Maintenance:Ordinarily, optimal clinical response is achieved at daily doses below 35 mg/kg. Combination Therapy: Tegretol may be used alone or with other anticonvulsants. When added to existing anticonvulsant therapy, the drug should be added gradually while the other anticonvulsants are maintained or gradually decreased, except phenytoin, which may have to be increased. © The Swiss Pharmacy, Geneva Switzerland
  7. 7. Generic Tegretol Tablets Recommended Dosage Trigeminal Neuralgia Adult Dosage: Initial: On the first day, 100 mg twice a day for a total daily dose of 200 mg. This daily dose may be increased by up to 200 mg/day using increments of 100 mg every 12 hours, only as needed to achieve freedom from pain. Do not exceed 1200 mg daily. Maintenance: Control of pain can be maintained in most patients with 400-800 mg daily. However, some patients may be maintained on as little as 200 mg daily, while others may require as much as 1200 mg daily. © The Swiss Pharmacy, Geneva Switzerland
  8. 8. Generic Tegretol Tablets Contraindications Generic Tegretol Tablets (Zeptol Tablets) is contraindicated in patients with the following conditions: ➔Hypersensitivity to Carbamazepine, or any inactive component of this medication. ➔In patients with a history of previous bone marrow depression. ➔In patients with a known sensitivity to any of the tricyclic compounds, such as amitriptyline, desipramine, imipramine, protriptyline, nortriptyline, etc © The Swiss Pharmacy, Geneva Switzerland
  9. 9. Generic Tegretol Tablets Contraindications Generic Tegretol Tablets (Zeptol Tablets) is contraindicated in patients with the following conditions: ➔Its use with monoamine oxidase inhibitors is not recommended ➔Coadministration of carbamazepine with nefazodone is contraindicated. © The Swiss Pharmacy, Geneva Switzerland
  10. 10. Generic Tegretol Tablets Side Effects of Generic Tegretol Tablets The most common side effects of Generic Tegretol (Zeptol Tablets) are dizziness, drowsiness, unsteadiness, headache, ataxia, fatigue, diplopia, leukopenia, oedema, fluid retention, weight increase, hyponatraemia and blood osmolarity decreased, nausea, vomiting , and allergic skin reactions (dermatitis allergic, urticaria). © The Swiss Pharmacy, Geneva Switzerland
  11. 11. Generic Tegretol Tablets Warnings And Precautions ➔Haematological effects: Agranulocytosis and aplastic anaemia have been associated with Tegretol; however, due to the very low incidence of these conditions, meaningful risk estimates for Tegretol are difficult to obtain. . ➔Serious dermatologic reactions: Serious dermatologic reactions, including toxic epidermal necrolysis (TEN; also known as Lyell’s syndrome) and Stevens-Johnson syndrome (SJS), have been reported very rarely with Tegretol. ➔Seizures: Tegretol should be used with caution in patients with mixed seizures which includes absences, either typical or atypical. © The Swiss Pharmacy, Geneva Switzerland
  12. 12. Generic Tegretol Tablets Warnings And Precautions ➔Other dermatologic reactions: Mild skin reactions, e.g. isolated macular or maculopapular exanthema, can also occur and are mostly transient and not hazardous. They usually disappear within a few days or weeks, either during the continued course of treatment or following a decrease in dosage. ➔Renal function: Baseline and periodic complete urinalysis and BUN determinations are recommended. ➔Anticholinergic effects: Tegretol has shown mild anticholinergic activity. Patients with increased intraocular pressure should therefore be closely observed during therapy. © The Swiss Pharmacy, Geneva Switzerland
  13. 13. Generic Tegretol Tablets Warnings And Precautions ➔Psychiatric effects: The possibility of activation of a latent psychosis and, in elderly patients, of confusion or agitation should be borne in mind. An analysis of reports of suicidality from placebo-controlled clinical studies of eleven medicines used to treat epilepsy as well as psychiatric disorders, and other conditions revealed that patients receiving an ti-epileptic drugs had approximately twice the risk of suicidal behaviour or ideation (0.43%) compared to patients receiving placebo (0.22%). ➔Endocrinological effects: The reliability of hormonal contraceptives may be adversely affected by Tegretol and women of childbearing age should be advised to consider using alternative forms of birth control while taking Tegretol. © The Swiss Pharmacy, Geneva Switzerland
  14. 14. Generic Tegretol Tablets Overdose Symptoms The first signs and symptoms of overdose appear after 1 to 3 hours. Neuromuscular disturbances are the most prominent. Cardiovascular disorders are generally milder, and severe cardiac complications occur only when very high doses (>60 g) have been ingested. © The Swiss Pharmacy, Geneva Switzerland
  15. 15. Generic Tegretol Tablets Overdose Symptoms Respiration: Irregular breathing, respiratory depression. Cardiovascular System: Tachycardia, hypotension or hypertension, shock, conduction disorders. Nervous System and Muscles: Impairment of consciousness ranging in severity to deep coma. Convulsions, especially in small children. Motor restlessness, muscular twitching, tremor, athetoid movements, opisthotonos, ataxia, drowsiness, dizziness, mydriasis, nystagmus, adiadochokinesia, ballism, psychomotor disturbances, dysmetria. Initial hyperreflexia, followed by hyporeflexia. Gastrointestinal Tract: Nausea, vomiting. © The Swiss Pharmacy, Geneva Switzerland
  16. 16. Generic Tegretol Tablets Overdose Symptoms Kidneys and Bladder: Anuria or oliguria, urinary retention. Laboratory Findings: Isolated instances of overdosage have included leukocytosis, reduced leukocyte count, glycosuria, and acetonuria. EEG may show dysrhythmias. Combined Poisoning: When alcohol, tricyclic antidepressants, barbiturates, or hydantoins are taken at the same time, the signs and symptoms of acute poisoning with Tegretol may be aggravated or modified. © The Swiss Pharmacy, Geneva Switzerland
  17. 17. Generic Tegretol Tablets Overdose Treatment In cases of severe poisoning is critically dependent upon prompt elimination of Generic Tegretol which may be achieved by inducing vomiting, irrigating the stomach, and by taking appropriate steps to diminish absorption. If these measures cannot be implemented without risk on the spot, the patient should be transferred at once to a hospital, while ensuring that vital functions are safeguarded. There is no specific antidote. © The Swiss Pharmacy, Geneva Switzerland
  18. 18. Generic Tegretol Tablets Zeptol Tablets manufactured by Sun Pharmaceuticals For more information click here © The Swiss Pharmacy, Geneva Switzerland
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×