Generic Nasonex Nasal Spray for Treatment of  Nasal Polyps,  Allergic Rhinitis  and Seasonal Allergic Rhinitis
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Generic Nasonex Nasal Spray for Treatment of Nasal Polyps, Allergic Rhinitis and Seasonal Allergic Rhinitis

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Generic Nasonex Nasal Spray (Metaspray Nasal Spray) is a corticosteroid used in the treatment of Nasal Symptoms of Allergic Rhinitis in patients 2 years of age and older, treatment of Nasal ...

Generic Nasonex Nasal Spray (Metaspray Nasal Spray) is a corticosteroid used in the treatment of Nasal Symptoms of Allergic Rhinitis in patients 2 years of age and older, treatment of Nasal Congestion Associated with Seasonal Allergic Rhinitis in patients 2 years of age and older, Prophylaxis of Seasonal Allergic Rhinitis in patients 12 years of age and older and treatment of Nasal Polyps in patients 18 years of age and older.

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Generic Nasonex Nasal Spray for Treatment of Nasal Polyps, Allergic Rhinitis and Seasonal Allergic Rhinitis Presentation Transcript

  • 1. Generic Nasonex Nasal Spray Generic Nasonex Nasal Spray (Metaspray Nasal Spray) is a corticosteroid used in the treatment of Nasal Symptoms of Allergic Rhinitis in patients 2 years of age and older, treatment of Nasal Congestion Associated with Seasonal Allergic Rhinitis in patients 2 years of age and older, Prophylaxis of Seasonal Allergic Rhinitis in patients 12 years of age and older and treatment of Nasal Polyps in patients 18 years of age and older. © The Swiss Pharmacy, Geneva Switzerland
  • 2. Generic Nasonex Nasal Spray Active Ingredient The active pharmaceutical ingredient contained in Generic Nasonex Nasal Spray is Mometasone Furoate. Each spray of Generic Nasonex contains 50 mcg of Mometasone Furoate. © The Swiss Pharmacy, Geneva Switzerland
  • 3. Generic Nasonex Nasal Spray Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  • 4. Generic Nasonex Nasal Spray Recommended Dosage Treatment of Allergic Rhinitis: Adults and children over 12 years of age: 2 sprays (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 200 mcg). Children 2 to 11 years of age: 1 spray (50 mcg of Mometasone Furoate) in each nostril once daily (total daily dose of 100 mcg). © The Swiss Pharmacy, Geneva Switzerland
  • 5. Generic Nasonex Nasal Spray Recommended Dosage Treatment of Nasal Congestion Associated with Seasonal Allergic Rhinitis: Adults and Children 12 Years of Age and Older: Two sprays (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 200 mcg). Children 2 to 11 Years of Age: One spray (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 100 mcg) © The Swiss Pharmacy, Geneva Switzerland
  • 6. Generic Nasonex Nasal Spray Recommended Dosage Prophylaxis of Seasonal Allergic Rhinitis: Adults and Children 12 Years of Age and Older: The recommended dose for prophylaxis treatment of nasal symptoms of seasonal allergic rhinitis is 2 sprays (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 200 mcg). In patients with a known seasonal allergen that precipitates nasal symptoms of seasonal allergic rhinitis, prophylaxis with Generic Nasonex Nasal Spray 50 mcg (200 mcg/day) is recommended 2 to 4 weeks prior to the anticipated start of the pollen season. © The Swiss Pharmacy, Geneva Switzerland
  • 7. Generic Nasonex Nasal Spray Recommended Dosage Treatment of Nasal Polyps: Adults 18 Years of Age and Older: The recommended dose for the treatment of nasal polyps is 2 sprays (50 mcg of Mometasone Furoate in each spray) in each nostril twice daily (total daily dose of 400 mcg). A dose of 2 sprays (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 200 mcg) is also effective in some patients. © The Swiss Pharmacy, Geneva Switzerland
  • 8. Generic Nasonex Nasal Spray Contraindications Generic Nasonex Nasal Spray (Metaspray Nasal Spray) is contraindicated in patients with the following conditions: ➔Hypersensitivity to Mometasone Furoate, or any inactive component of this medication. © The Swiss Pharmacy, Geneva Switzerland
  • 9. Generic Nasonex Nasal Spray Side Effects of Generic Nasonex Nasal Spray The most common side effects of Generic Nasonex Nasal Spray (Metaspray Nasal Spray) are Epistaxis, ulcerations, Candida albicans infection, impaired wound healing, Cataracts and glaucoma, Immunosuppression, Hypothalamic-pituitary-adrenal (HPA) axis effects, including growth reduction © The Swiss Pharmacy, Geneva Switzerland
  • 10. Generic Nasonex Nasal Spray Warnings And Precautions Local Nasal Effects: ➔Epistaxis:In clinical studies, epistaxis was observed more frequently in patients with allergic rhinitis with Generic Nasonex Nasal Spray than those who received placebo ➔Candida Infection: In clinical studies with Nasonex Nasal Spray 50 mcg, the development of localized infections of the nose and pharynx with Candida albicans has occurred. When such an infection develops, use of Generic Nasonex Nasal Spray 50 mcg should be discontinued and appropriate local or systemic therapy instituted, if needed. © The Swiss Pharmacy, Geneva Switzerland
  • 11. Generic Nasonex Nasal Spray Warnings And Precautions Local Nasal Effects: ➔Nasal Septum Perforation: Instances of nasal septum perforation have been reported following the intranasal application of corticosteroids. As with any long term topical treatment of the nasal cavity, patients using Generic Nasonex Nasal Spray 50 mcg over several months or longer should be examined periodically for possible changes in the nasal mucosa. ➔Impaired Wound Healing: Because of the inhibitory effect of corticosteroids on wound healing, patients who have experienced recent nasal septum ulcers, nasal surgery, or nasal trauma should not use a nasal corticosteroid until healing has occurred. © The Swiss Pharmacy, Geneva Switzerland
  • 12. Generic Nasonex Nasal Spray Warnings And Precautions ➔Glaucoma and Cataracts: Nasal and inhaled corticosteroids may result in the development of glaucoma and/or cataracts. Therefore, close monitoring is warranted in patients with a change in vision or with a history of increased intraocular pressure, glaucoma, and/or cataracts. ➔Hypersensitivity Reactions: Hypersensitivity reactions including instances of wheezing may occur after the intranasal administration of mometasone furoate monohydrate. Discontinue Generic Nasonex Nasal Spray if such reactions occur © The Swiss Pharmacy, Geneva Switzerland
  • 13. Generic Nasonex Nasal Spray Warnings And Precautions ➔Immunosuppression: Persons who are on medications which suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in nonimmune children or adults on corticosteroids. In such children or adults who have not had these diseases, particular care should be taken to avoid exposure. © The Swiss Pharmacy, Geneva Switzerland
  • 14. Generic Nasonex Nasal Spray Warnings And Precautions ➔Hypothalamic-Pituitary-Adrenal Axis Effect: Hypercorticism and Adrenal Suppression: When intranasal steroids are used at higher than recommended dosages or in susceptible individuals at recommended dosages, systemic corticosteroid effects such as hypercorticism and adrenal suppression may appear. If such changes occur, the dosage of Generic Nasonex Nasal Spray should be discontinued slowly, consistent with accepted procedures for discontinuing oral corticosteroid therapy. © The Swiss Pharmacy, Geneva Switzerland
  • 15. Generic Nasonex Nasal Spray Warnings And Precautions ➔Effect on Growth :Corticosteroids may cause a reduction in growth velocity when administered to pediatric patients. Monitor the growth routinely of pediatric patients receiving Generic Nasonex Nasal Spray. To minimize the systemic effects of intranasal corticosteroids, including Generic Nasonex Nasal Spray, titrate each patient’s dose to the lowest dosage that effectively controls his/her symptoms © The Swiss Pharmacy, Geneva Switzerland
  • 16. Generic Nasonex Nasal Spray Overdose Symptoms Intranasal administration of 1600 mcg (4 times the recommended dose of Generic Nasonex Nasal Spray 50 mcg) for the treatment of nasal polyps in patients 18 years of age and older daily for 29 days, to healthy human volunteers, showed no increased incidence of adverse events. Single intranasal doses up to 4000 mcg and oral inhalation doses up to 8000 mcg have been studied in human volunteers with no adverse effects reported. Chronic over dosage with any corticosteroid may result in signs or symptoms of hypercorticism. © The Swiss Pharmacy, Geneva Switzerland
  • 17. Generic Nasonex Nasal Spray Overdose Treatment Because of low systemic bioavailability, and an absence of acute drug related systemic findings in clinical studies, overdose is unlikely to require any therapy other than observation. © The Swiss Pharmacy, Geneva Switzerland
  • 18. Generic Nasonex Nasal Spray Metaspray Nasal Spray Manufactured by Cipla Ltd., India For more information click here © The Swiss Pharmacy, Geneva Switzerland