Generic Fosamax Tablets 
Generic Fosamax (Osteofos Tablets) is used to 
prevent osteoporosis in postmenopausal women, 
and...
Generic Fosamax Tablets 
Chemical Structure 
© The Swiss Pharmacy, Geneva Switzerland
Generic Fosamax Tablets 
Indications 
Generic Fosamax (Osteofos Tablets) is 
used to treat the following indications: 
In ...
Generic Fosamax Tablets 
Indications 
For the treatment of osteoporosis in men 
to prevent fractures. 
For the treatment a...
Generic Fosamax Tablets 
Active Ingredient 
The active pharmaceutical ingredient 
contained in Generic Fosamax (Osteofos 
...
Generic Fosamax Tablets 
Recommended Dosage 
Generic Fosamax must be taken at 
least one half hour before the first food, ...
Generic Fosamax Tablets 
Recommended Dosage 
The recommended dosage of Generic Fosamax 
(Alendronate Tablets) for the trea...
Generic Fosamax Tablets 
Recommended Dosage 
➔Treatment and Prevention of Glucocorticoid- 
Induced Osteoporosis in Men, Pr...
Generic Fosamax Tablets 
Contraindications 
Generic Fosamax (Osteofos Tablets) is 
contraindicated in patients with the fo...
Generic Fosamax Tablets 
Side Effects of Generic Fosamax 
The following upper gastrointestinal side 
effects were reported...
Generic Fosamax Tablets 
Side Effects of Generic Fosamax 
Additionally, the following side effects were 
also reported in ...
Generic Fosamax Tablets 
Warnings And Precautions 
➔Generic Fosamax like other orally administered 
bisphosphonates, may c...
Generic Fosamax Tablets 
Warnings And Precautions 
➔Hypocalcemia must be corrected before initiating therapy 
with Generic...
Generic Fosamax Tablets 
Warnings And Precautions 
➔Atypical, low-energy, or low trauma fractures of the 
femoral shaft ha...
Generic Fosamax Tablets 
Overdose Symptoms 
Hypocalcemia, hypophosphatemia, and upper 
gastrointestinal adverse events, su...
Generic Fosamax Tablets 
Osteofos Tablets manufactured 
by Cipla Ltd., India 
For more information click here 
© The Swiss...
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Generic Fosamax for Treatment of Osteoporosis and Paget's Disease

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Generic Fosamax (Osteofos Tablets) is used to prevent osteoporosis in postmenopausal women, and to treat Paget's disease of the bone. Generic Fosamax is also used to treat or prevent osteoporosis in men, premenopausal women and postmenopausal women using oestrogen who are receiving corticosteroid medicines, such as prednisone and dexamethasone.

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Generic Fosamax for Treatment of Osteoporosis and Paget's Disease

  1. 1. Generic Fosamax Tablets Generic Fosamax (Osteofos Tablets) is used to prevent osteoporosis in postmenopausal women, and to treat Paget's disease of the bone. Generic Fosamax is also used to treat or prevent osteoporosis in men, premenopausal women and postmenopausal women using oestrogen who are receiving corticosteroid medicines, such as prednisone and dexamethasone. © The Swiss Pharmacy, Geneva Switzerland
  2. 2. Generic Fosamax Tablets Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  3. 3. Generic Fosamax Tablets Indications Generic Fosamax (Osteofos Tablets) is used to treat the following indications: In postmenopausal women for the treatment of osteoporosis to prevent fractures, including those of the hip and spine (vertebral compression fractures). In postmenopausal women who are at risk of developing osteoporosis Generic Fosamax is indicated for the prevention of osteoporosis to reduce the risk of future fracture. © The Swiss Pharmacy, Geneva Switzerland
  4. 4. Generic Fosamax Tablets Indications For the treatment of osteoporosis in men to prevent fractures. For the treatment and prevention of glucocorticoid-induced osteoporosis in men, premenopausal women and postmenopausal women receiving oestrogen. For treatment of Paget’s disease of bone in men and women. © The Swiss Pharmacy, Geneva Switzerland
  5. 5. Generic Fosamax Tablets Active Ingredient The active pharmaceutical ingredient contained in Generic Fosamax (Osteofos Tablets) is Alendronate Sodium. © The Swiss Pharmacy, Geneva Switzerland
  6. 6. Generic Fosamax Tablets Recommended Dosage Generic Fosamax must be taken at least one half hour before the first food, beverage, or medication of the day with plain water only. To facilitate delivery to the stomach and thus reduce the potential for oesophageal irritation, Generic Fosamax should only be swallowed upon arising for the day with a full glass of water and patients should not lie down for at least 30 minutes and until after their first food of the day. © The Swiss Pharmacy, Geneva Switzerland
  7. 7. Generic Fosamax Tablets Recommended Dosage The recommended dosage of Generic Fosamax (Alendronate Tablets) for the treatment of various indications is given below: ➔Treatment of Osteoporosis in Postmenopausal Women and in Men: The recommended dosage of Generic Fosamax is one 70 mg tablet taken orally once weekly. ➔Prevention of Osteoporosis in Postmenopausal Women: The recommended dose of Generic Fosamax is one 5 mg tablet taken orally once a day. © The Swiss Pharmacy, Geneva Switzerland
  8. 8. Generic Fosamax Tablets Recommended Dosage ➔Treatment and Prevention of Glucocorticoid- Induced Osteoporosis in Men, Premenopausal Women and Postmenopausal Women Receiving Oestrogen: The recommended dosage of Generic Fosamax is one 5 mg tablet taken orally once a day. ➔Paget’s Disease of Bone in Men and Women: The recommended treatment regimen is 40 mg once a day for six months. © The Swiss Pharmacy, Geneva Switzerland
  9. 9. Generic Fosamax Tablets Contraindications Generic Fosamax (Osteofos Tablets) is contraindicated in patients with the following conditions: ➔Hypersensitivity to Alendronate Sodium, or any inactive component of this medication. ➔Abnormalities of the oesophagus which delay oesophageal emptying such as stricture or achalasia. ➔Inability to stand or sit upright for at least 30 minutes. ➔Hypocalcaemia © The Swiss Pharmacy, Geneva Switzerland
  10. 10. Generic Fosamax Tablets Side Effects of Generic Fosamax The following upper gastrointestinal side effects were reported in 1% or more of patients treated with Generic Fosamax 10 mg/day and at a greater incidence than in patients treated with placebo: abdominal pain, dyspepsia, oesophageal ulcer, dysphagia and abdominal distention. Rarely, rash and erythema have occurred. © The Swiss Pharmacy, Geneva Switzerland
  11. 11. Generic Fosamax Tablets Side Effects of Generic Fosamax Additionally, the following side effects were also reported in 1% or more of patients treated with Generic Fosamax 10 mg/day and at a greater incidence than in patients treated with placebo: musculoskeletal (bone, muscle or joint) pain, constipation, diarrhoea, flatulence, and headache. © The Swiss Pharmacy, Geneva Switzerland
  12. 12. Generic Fosamax Tablets Warnings And Precautions ➔Generic Fosamax like other orally administered bisphosphonates, may cause local irritation of the upper gastrointestinal mucosa. Because of these possible irritant effects and a potential for worsening of the underlying disease, caution should be used when Generic Fosamax is given to patients with active upper gastrointestinal problems (such as known Barrett's esophagus, dysphagia, other esophageal diseases, gastritis, duodenitis, or ulcers). ➔The risk of severe esophageal side effects appears to be greater in patients who lie down after taking oral bisphosphonates including Generic Fosamax and/or who fail to swallow oral bisphosphonates including Generic Fosamax with the recommended full glass (180 to 250 ml) of water. © The Swiss Pharmacy, Geneva Switzerland
  13. 13. Generic Fosamax Tablets Warnings And Precautions ➔Hypocalcemia must be corrected before initiating therapy with Generic Fosamax. Other disorders affecting mineral metabolism (such as vitamin D deficiency) should also be effectively treated. ➔Severe and occasionally incapacitating bone, joint, and/or muscle pain has been reported in patients taking bisphosphonates (including Generic Fosamax (Alendronate))that are approved for the prevention and treatment of osteoporosis. ➔Osteonecrosis of the jaw (ONJ), which can occur spontaneously, is generally associated with tooth extraction and/or local infection with delayed healing, and has been reported in patients taking bisphosphonates, including Generic Fosamax. © The Swiss Pharmacy, Geneva Switzerland
  14. 14. Generic Fosamax Tablets Warnings And Precautions ➔Atypical, low-energy, or low trauma fractures of the femoral shaft have been reported in bisphosphonate-treated patients. ➔Generic Fosamax is not recommended for patients with creatinine clearance <35 mL/min ➔The risk versus benefit of Generic Fosamax for treatment at daily dosages of glucocorticoids less than 7.5 mg of prednisone or equivalent has not been established. Before starting treatment, the gonadal hormonal status of both men and women should be ascertained and appropriate replacement considered. © The Swiss Pharmacy, Geneva Switzerland
  15. 15. Generic Fosamax Tablets Overdose Symptoms Hypocalcemia, hypophosphatemia, and upper gastrointestinal adverse events, such as upset stomach, heartburn, esophagitis, gastritis, or ulcer, may result from oral overdosage. Milk or antacids should be given to bind Alendronate. Due to the risk of esophageal irritation, vomiting should not be induced and the patient should remain fully upright. Dialysis would not be beneficial. © The Swiss Pharmacy, Geneva Switzerland
  16. 16. Generic Fosamax Tablets Osteofos Tablets manufactured by Cipla Ltd., India For more information click here © The Swiss Pharmacy, Geneva Switzerland
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