Generic Dozile Tablets for Relief of Sleeplessness

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Generic Dozile Tablets (Doxinate Tablets) is used for the temporary relief of sleeplessness. It is also used for the treatment of nausea and vomiting during pregnancy.

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Generic Dozile Tablets for Relief of Sleeplessness

  1. 1. Generic Dozile Tablets Generic Dozile Tablets (Doxinate Tablets) is used for the temporary relief of sleeplessness because of its sedative effect. It is also used for the relief of nausea and vomiting during pregnancy. © The Swiss Pharmacy, Geneva Switzerland
  2. 2. Generic Dozile Tablets Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  3. 3. Generic Dozile Tablets Indications Generic Dozile Tablets (Doxylamine Succinate) is an ethanolamine derivative antihistamine. Because of its sedative effect, it is used for the temporary relief of sleeplessness. It is also used for the relief of nausea and vomiting during pregnancy. Generic Dozile is also used in combination with antitussives and decongestants for the temporary relief of cold and cough symptoms. © The Swiss Pharmacy, Geneva Switzerland
  4. 4. Generic Dozile Tablets Indications It is an antihistamine with hypnotic, anticholinergic, antimuscarinic and local anaesthetic effects. Duration of action is 6 to 8 hours. © The Swiss Pharmacy, Geneva Switzerland
  5. 5. Generic Dozile Tablets Active Ingredient The active pharmaceutical ingredient contained in Generic Dozile Tablets is Doxylamine Succinate. Doxinate contains Doxylamine Succinate 10 mg and Pyridoxine HCl 10 mg. Doxinate Plus contains Doxylamine Succinate 10 mg, Pyridoxine HCl 10 mg and Folic Acid 2.5 mg. Doxinate OD contains Doxylamine Succinate 20 mg and Pyridoxine HCl 20 mg. © The Swiss Pharmacy, Geneva Switzerland
  6. 6. Generic Dozile Tablets Recommended Dosage The recommended dosage for the treatment of various indications is given below: ➔Relief of Insomnia: 1 tablet 30 minutes before retiring, or as directed by the doctor. Maximum stated dose should not be exceeded. Generic Dozile is recommended for occasional use only i.e. for periods of no longer than a week at a time. If sleeplessness persists, consult your doctor. Generic Dozile is not recommended for children under 12 years of age. © The Swiss Pharmacy, Geneva Switzerland
  7. 7. Generic Dozile Tablets Recommended Dosage ➔For Relief Of Nausea And Vomiting During Pregnancy: 2 tablets of Generic Dozile (Doxinate / Doxinate Plus Tablets) at bed time, one in the morning and one in the afternoon if required or as prescribed by the doctor. Maximum upto 10 Tablets of Doxinate / Doxinate Plus Tablets can be safely be given in divided doses. © The Swiss Pharmacy, Geneva Switzerland
  8. 8. Generic Dozile Tablets Contraindications Generic Dozile (Doxinate / Doxinate Plus Tablets) is contraindicated in patients with the following conditions: ➔Hypersensitivity to Doxylamine succinate, other ethanolamine derivative antihistamines or any inactive component of this medication. © The Swiss Pharmacy, Geneva Switzerland
  9. 9. Generic Dozile Tablets Side Effects of Generic Dozile Tablets The most common side effects of Generic Dozile Tablets (Doxylamine Succinate) are drowsiness, vertigo, nervousness, epigastric pain, headache, palpitation, diarrhea, disorientation, irritability, convulsions, urinary retention or insomnia, nausea with or without vomiting, and abdominal pain. © The Swiss Pharmacy, Geneva Switzerland
  10. 10. Generic Dozile Tablets Warnings And Precautions ➔Caution should be used if taken with alcohol. ➔Due to the anticholinergic properties of antihistamines, caution should be used when Generic Dozile is taken concurrently with other medications ➔Caution should be taken by those with narrow angle or open-angle glaucoma, urinary retention, prostate enlargement, pyloroduodenal obstruction, epilepsy or severe cardiovascular disorders. ➔Doxylamine may suppress positive skin test results. ➔Doxylamine causes drowsiness. Patients should not drive or operate machinery if affected. © The Swiss Pharmacy, Geneva Switzerland
  11. 11. Generic Dozile Tablets Warnings And Precautions ➔Use of Dozile should be avoided during lactation. First generation antihistamines may inhibit lactation because of their anticholinergic actions. ➔Generic Dozile is not recommended for children under 12 years of age. The safety and efficacy of Doxylamine succinate as a night time sleep aid in children younger than 12 years of age have not been established. ➔Generic Dozile Tablets (Doxinate / Doxinate Plus) should be administered during pregnancy only if strictly required. © The Swiss Pharmacy, Geneva Switzerland
  12. 12. Generic Dozile Tablets Overdose Symptoms Generic Dozile (Doxinate Tablets) overdose produces signs and symptoms of anticholinergic toxicity. Acute overdose of Doxylamine Succinate may cause various reactions including dry mouth, fixed and dilated pupils, flushing, gastrointestinal symptoms, insomnia, nervousness, euphoria, irritability, tremors, nightmares and hallucinations © The Swiss Pharmacy, Geneva Switzerland
  13. 13. Generic Dozile Tablets Overdose Symptoms Other overdose signs and symptoms may include CNS depression or stimulation, impaired consciousness, seizures, tachycardia, mydriasis and a psychosis similar to that in catatonic stupor. Rhabdomyolysis with impairment of renal function and acute renal failure has been observed. Fatalities have been reported from Doxylamine Succinate overdose. © The Swiss Pharmacy, Geneva Switzerland
  14. 14. Generic Dozile Tablets Overdose Treatment Patients should be monitored for any abnormalities of vital signs. Adequacy of ventilation and blood pressure should be assessed and full supportive care, including oxygen and assisted ventilation, be provided if required. The patient should be observed for evidence of rhabdomyolysis. Adequate fluid replacement must be provided and good urine output maintained. Gastric lavage should be considered if it can be performed soon after ingestion, generally within 60 minutes. Most patients recover with symptomatic and supportive care. © The Swiss Pharmacy, Geneva Switzerland
  15. 15. Generic Dozile Tablets Doxinate / Doxinate Plus Tablets from Svizera Healthcare, India For more information click here © The Swiss Pharmacy, Geneva Switzerland

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