Generic Advair Inhaler for treatment of Asthma and COPD

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Generic Advair Inhaler (Seroflo Inhaler) is used to treat Asthma and Chronic obstructive Pulmonary Disease (COPD).

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Generic Advair Inhaler for treatment of Asthma and COPD

  1. 1. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Generic Advair Inhaler (Seroflo Inhaler) is a combination products containing Fluticasone Propionate and Salmeterol Xinafoate which is used for the treatment of asthma in patients aged 12 years and older. It is also used in the treatment of Chronic Obstructive Pulmonary Disease (COPD).
  2. 2. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland The active pharmaceutical ingredients contained in Generic Advair Inhaler are Fluticasone Propionate and Salmeterol Xinafoate. Seroflo inhalers contain Salmeterol Xinafoate 25 mcg (fixed) and the quantity of Fluticasone Propionate is 50 mcg or 125 mcg. Seroflo inhaler contains 120 metered doses. Seroflo multihalers contain Salmeterol Xinafoate 50 mcg (fixed) and the quantity of Fluticasone Propionate is 250 mcg or 500 mcg. Seroflo multihaler contains 30 metered doses. Active Ingredient
  3. 3. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Chemical Structure (Fluticasone)
  4. 4. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Chemical Structure (Salmeterol)
  5. 5. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Asthma: Adults and Adolescents (12 years and older): Seroflo 50 Inhaler: Two inhalations twice daily Seroflo 125 Inhaler: Two inhalations twice daily Asthma: Children (4 years and older) Seroflo 50 Inhaler: Two inhalations twice daily Not recommended for children below 4 years of age. COPD: Adults: Seroflo 125 inhaler: Two inhalations twice daily Seroflo 250 Inhaler: Two inhalations twice daily Recommended Dosage
  6. 6. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Contraindications Generic Advair Inhaler (Seroflo Inhaler) is contraindicated in patients with the following conditions: ➔Hypersensitivity to Fluticasone Propionate, Salmeterol Xinafoate, or any inactive component of this medication. ➔Contraindicated in the primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required.
  7. 7. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Side Effects of Generic Advair Inhaler Ear, Nose, & Throat: Upper respiratory tract infection, Throat irritation, Upper respiratory inflammation, Hoarseness/dysphonia Lower Respiratory: Viral respiratory infections Neurology: Headaches Dizziness Gastrointestinal: Nausea & vomiting, Viral gastrointestinal infections, Gastrointestinal signs and symptoms Non-Site Specific: Pain
  8. 8. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Side Effects of Generic Advair Inhaler Musculoskeletal: Musculoskeletal pain Muscle pain Drug interaction, Overdose, and Trauma: Muscle injuries Reproduction: Menstruation symptoms Psychiatry: Intoxication and hangover
  9. 9. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Warnings And Precautions ➔Long-acting beta2-adrenergic agonists, such as salmeterol, one of the active ingredients in Generic Advair inhaler (Seroflo inhaler), may increase the risk of asthma- related death. Therefore, when treating patients with asthma, physicians should only prescribe Seroflo inhaler for patients not adequately controlled on other asthma- controller medications. ➔Treatment with Generic Advair inhaler should not be initiated in patients during rapidly deteriorating or potentially life-threatening episodes of asthma ➔Generic Advair inhaler should not be used to treat acute symptoms. ➔Increasing use of inhaled, short-acting beta2-agonists is a marker of deteriorating asthma.
  10. 10. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Warnings And Precautions ➔Generic Advair inhaler should not be used for transferring patients from systemic corticosteroid therapy ➔Generic Advair inhaler should not be used in conjunction with an inhaled, long-acting beta2-agonist. ➔The recommended dosage should not be exceeded. ➔As with other inhaled asthma medications, Generic Advair Inhaler can produce paradoxical bronchospasm, which may be life threatening ➔Immediate hypersensitivity reactions may occur after administration of Generic Advair inhaler, as demonstrated by cases of urticaria, angioedema, rash, and bronchospasm.
  11. 11. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Warnings And Precautions ➔Symptoms of laryngeal spasm, irritation, or swelling, such as stridor and choking, have been reported in patients receiving fluticasone propionate and salmeterol, components of Generic Advair inhaler. ➔Generic Advair inhaler, like all products containing sympathomimetic amines, should be used with caution in patients with cardiovascular disorders ➔Transfer of patients from systemic corticosteroid therapy to Generic Advair inhaler may unmask conditions previously suppressed by the systemic corticosteroid therapy, e.g., rhinitis, conjunctivitis, eczema, arthritis, and eosinophilic conditions
  12. 12. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Warnings And Precautions ➔Persons who are using drugs that suppress the immune system are more susceptible to infections than healthy individuals. ➔Lower respiratory tract infections, including pneumonia, have been reported in patients with COPD following the inhaled administration of corticosteroids, including 698 fluticasone propionate and Generic Advair Inhaler. ➔Because of the potential for drug interactions and the potential for increased risk of cardiovascular adverse events, the concomitant use of Generic Advair Inhaler with strong CYP 3A4 inhibitors (e.g., ketoconazole, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin) is not recommended
  13. 13. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Overdose Symptoms Generic Advair Inhaler (Seroflo inhaler) overdose symptoms may include: Chest pain (angina), High blood pressure (hypertension) or low blood pressure (hypotension), Nervousness, Headaches, Shakiness (tremors), Dry mouth, Feelings of a rapidly or forcefully beating heart (heart palpitations), Nausea, Dizziness, Insomnia or fatigue, Seizures, An irregular heart rhythm (arrhythmia) or a fast heart rate (tachycardia), Low potassium in the blood (hypokalemia), High blood sugar (hyperglycemia), Cardiac arrest .
  14. 14. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Overdose Treatment Treatment for Generic Advair Inhaler (Seroflo inhaler) overdose involves supportive care. Supportive care consists of treating the symptoms that occur as a result of the overdose. Supportive treatment options may include: Fluids through an intravenous line (IV), medications (such as beta blockers) to reverse the effects of Generic Advair.
  15. 15. Generic Advair Inhaler © The Swiss Pharmacy, Geneva Switzerland Seroflo Inhaler and Seroflo Multihaler from Cipla Ltd. For more information click here

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