Generic Accutane for Treatment of Moderate to Severe Acne

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Generic Accutane (Isotroin Capsules) an extremely powerful and potent acne-controlling medicine, is used in the treatment of moderate to severe acne that has failed other therapy.

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Generic Accutane for Treatment of Moderate to Severe Acne

  1. 1. Generic Accutane Capsules Generic Accutane (Isotroin Capsules) an extremely powerful and potent acne-controlling medicine, is used in the treatment of moderate to severe acne that has failed other therapy. © The Swiss Pharmacy, Geneva Switzerland
  2. 2. Generic Accutane Capsules Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  3. 3. Generic Accutane Capsules Active Ingredient The active ingredient present in Generic Accutane (Isotroin Capsules) is Isotretinoin. Isotroin Capsules are available in strengths of 10 mg and 20 mg. The 40 mg capsules are sold under the brand name Tretiva. © The Swiss Pharmacy, Geneva Switzerland
  4. 4. Generic Accutane Capsules Indications Generic Accutane (Isotroin Capsules) are indicated for the treatment of severe recalcitrant nodular acne. Nodules are inflammatory lesions with a diameter of 5 mm or greater. The nodules may become suppurative or hemorrhagic. “Severe,” by definition, means “many” as opposed to “few or several” nodules. © The Swiss Pharmacy, Geneva Switzerland
  5. 5. Generic Accutane Capsules Indications A single course of therapy for 15 to 20 weeks has been shown to result in complete and prolonged remission of disease in many patients. If a second course of therapy is needed, it should not be initiated until at least 8 weeks after completion of the first course. © The Swiss Pharmacy, Geneva Switzerland
  6. 6. Generic Accutane Capsules Dosage and Administration Generic Accutane Capsules (Isotretinoin) should be taken with a meal. he recommended dosage range for Accutane is 0.5 to 1.0 mg/kg/day given in two divided doses with food for 15 to 20 weeks. Failure to take Generic Accutane (Isotroin Capsules) with food will significantly decrease absorption. © The Swiss Pharmacy, Geneva Switzerland
  7. 7. Generic Accutane Capsules Contraindications Generic Accutane (Isotretinoin Capsules) are contraindicated in the following cases: Hypersensitivity to Isotretinoin or any inactive component of the preparation. Pregnancy © The Swiss Pharmacy, Geneva Switzerland
  8. 8. Generic Accutane Capsules Warnings Psychiatric Disorders Generic Accutane may cause depression, psychosis and, rarely, suicidal ideation, suicide attempts, suicide, and aggressive and/or violent behaviors. Pseudotumor Cerebri Generic Accutane use has been associated with a number of cases of pseudotumor cerebri (benign intracranial hypertension), some of which involved concomitant use of tetracyclines. Concomitant treatment with tetracyclines should therefore be avoided. © The Swiss Pharmacy, Geneva Switzerland
  9. 9. Generic Accutane Capsules Warnings And Precautions ➔Acute pancreatitis has been reported in patients with either elevated or normal serum triglyceride levels. ➔Elevations of serum triglycerides in excess of 800 mg/dL have been reported in patients treated with Accutane. ➔Impaired hearing has been reported in patients taking Generic Accutane; in some cases, the hearing impairment has been reported to persist after therapy has been discontinued. ➔Clinical hepatitis considered to be possibly or probably related to Generic Accutane therapy has been reported. ➔Generic Accutane has been associated with inflammatory bowel disease (including regional ileitis) in patients without a prior history of intestinal disorders. © The Swiss Pharmacy, Geneva Switzerland
  10. 10. Generic Accutane Capsules Warnings And Precautions ➔Effects of multiple courses of Generic Accutane on the developing musculoskeletal system are unknown. ➔A high prevalence of skeletal hyperostosis was noted in clinical trials for disorders of keratinization with a mean dose of 2.24 mg/kg/day. ➔There are spontaneous reports of premature epiphyseal closure in acne patients receiving recommended doses of Generic Accutane. ➔All patients undergoing Generic Accutane therapy and experiencing visual difficulties should discontinue treatment and have an ophthalmological examination ➔Decreased night vision has been reported during Accutane therapy and in some instances the event has persisted after therapy was discontinued. © The Swiss Pharmacy, Geneva Switzerland
  11. 11. Generic Accutane Capsules Warnings And Precautions ➔Corneal opacities have occurred in patients receiving Generic Accutane for acne and more frequently when higher drug dosages were used in patients with disorders of keratinization. The corneal opacities that have been observed in clinical trial patients treated with Generic Accutane have either completely resolved or were resolving at follow-up 6 to 7 weeks after discontinuation of the drug © The Swiss Pharmacy, Geneva Switzerland
  12. 12. Generic Accutane Capsules Side Effects of Generic Accutane (Isotroin Capsules) Body as a Whole Allergic reactions, including vasculitis, systemic hypersensitivity, edema, fatigue, lymphadenopathy, weight loss Cardiovascular Palpitation, tachycardia, vascular thrombotic disease, stroke Endocrine/Metabolic Hypertriglyceridemia, alterations in blood sugar levels © The Swiss Pharmacy, Geneva Switzerland
  13. 13. Generic Accutane Capsules Side Effects of Generic Accutane (Isotroin Capsules) Gastrointestinal Inflammatory bowel disease, hepatitis , pancreatitis, bleeding and inflammation of the gums, colitis, esophagitis/esophageal ulceration, ileitis, nausea, other nonspecific gastrointestinal symptoms Hematologic Allergic reactions, anemia, thrombocytopenia, neutropenia, rare reports of agranulocytosis © The Swiss Pharmacy, Geneva Switzerland
  14. 14. Generic Accutane Capsules Side Effects of Generic Accutane (Isotroin Capsules) Musculoskeletal Skeletal hyperostosis, calcification of tendons and ligaments, premature epiphyseal closure, decreases in bone mineral density, musculoskeletal symptoms (sometimes severe) including back pain, myalgia, and arthralgia, transient pain in the chest, arthritis, tendonitis, other types of bone abnormalities, elevations of CPK/rare reports of rhabdomyolysis. Neurological Pseudotumor cerebri, dizziness, drowsiness, headache, insomnia, lethargy, malaise, nervousness, paresthesias, seizures, stroke, syncope, weakness © The Swiss Pharmacy, Geneva Switzerland
  15. 15. Generic Accutane Capsules Side Effects of Generic Accutane (Isotroin Capsules) Psychiatric Suicidal ideation, suicide attempts, suicide, depression, psychosis, aggression, violent behaviors, emotional instability Reproductive System Abnormal menses Respiratory Bronchospasms, respiratory infection, voice alteration © The Swiss Pharmacy, Geneva Switzerland
  16. 16. Generic Accutane Capsules Side Effects of Generic Accutane (Isotroin Capsules) Skin and Appendages Acne fulminans, alopecia (which in some cases persists), bruising, cheilitis (dry lips), dry mouth, dry nose, dry skin, epistaxis, eruptive xanthomas, flushing, fragility of skin, hair abnormalities, hirsutism, hyperpigmentation and hypopigmentation, infections (including disseminated herpes simplex), nail dystrophy, paronychia, peeling of palms and soles, photoallergic/photosensitizing reactions, pruritus, pyogenic granuloma, rash (including facial erythema, seborrhea, and eczema), sunburn susceptibility increased, sweating, urticaria, vasculitis, abnormal wound healing © The Swiss Pharmacy, Geneva Switzerland
  17. 17. Generic Accutane Capsules Side Effects of Generic Accutane (Isotroin Capsules) Hearing Hearing impairment, tinnitus. Vision Corneal opacities, decreased night vision which may persist, cataracts, color vision disorder, conjunctivitis, dry eyes, eyelid inflammation, keratitis, optic neuritis, photophobia, visual disturbances Urinary System Glomerulonephritis, nonspecific urogenital findings © The Swiss Pharmacy, Geneva Switzerland
  18. 18. Generic Accutane Capsules Overdosage Symptoms Overdosage of Generic Accutane Capsules (Isotretinoin) has been associated with vomiting, facial flushing, cheilosis, abdominal pain, headache, dizziness, and ataxia. These symptoms quickly resolve without apparent residual effects. © The Swiss Pharmacy, Geneva Switzerland
  19. 19. Generic Accutane Capsules Isotroin Capsules manufactured in India by Cipla Ltd. For more information click here © The Swiss Pharmacy, Geneva Switzerland

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