Diane-35 for Contraception and Treatment of Severe Acne and Idiopathic Hirsutism

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Diane-35 is used as a oral contraceptive as well for the the treatment of signs of androgenisation in women, such as severe acne (involving inflammation or nodularity or risk of scarring) where …

Diane-35 is used as a oral contraceptive as well for the the treatment of signs of androgenisation in women, such as severe acne (involving inflammation or nodularity or risk of scarring) where prolonged oral antibiotics or local treatment alone has not been successful, or idiopathic hirsutism of mild to moderate degree.

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  • 1. Diane-35 Tablets Diane-35 Tablets are used as a oral contraceptive as well for the the treatment of signs of androgenisation in women, such as severe acne (involving inflammation or nodularity or risk of scarring) where prolonged oral antibiotics or local treatment alone has not been successful, or idiopathic hirsutism of mild to moderate degree. © The Swiss Pharmacy, Geneva Switzerland
  • 2. Diane-35 Tablets Active Ingredient The active pharmaceutical ingredients contained in Diane-35 Tablets are 2mg cyproterone acetate and 0.035mg ethinyl estradiol. © The Swiss Pharmacy, Geneva Switzerland
  • 3. Diane-35 Tablets Chemical Structure Cyproterone Acetate Structure © The Swiss Pharmacy, Geneva Switzerland
  • 4. Diane-35 Tablets Chemical Structure Ethinylestradiol Structure © The Swiss Pharmacy, Geneva Switzerland
  • 5. Diane-35 Tablets Recommended Dosage One tablet is to be taken daily. The tablets must be taken at about the same time every day, with some liquid as needed. Tablet taking should be continuous. One tablet of Diane-35 is to be taken daily for 21 consecutive days. Withdrawal bleeding should usually occur on day 2 to 3 after the last tablet is taken. Each subsequent pack is started after a 7 day tablet free interval. How to start Diane-35 Tablets: taking has to start on day 1 of the woman's natural cycle (i.e. the first day of her menstrual bleeding). © The Swiss Pharmacy, Geneva Switzerland
  • 6. Diane-35 Tablets Recommended Dosage Missed Dose: If you forget to take your tablet at the usual time, you must take it within the next 12 hours at the latest. If more than 12 hours have passed from the time that you normally take your tablet, you must discard the missed tablet and continue to take the remaining tablets in the pack at the usual time. © The Swiss Pharmacy, Geneva Switzerland
  • 7. Diane-35 Tablets Contraindications Generic Diane-35 Tablets are contraindicated in patients with the following conditions: ➔Hypersensitivity to cyproterone acetate and/or ethinyl estradiol, or any inactive component of this medication. ➔Personal or family history of confirmed, idiopathic venous thromboembolism (VTE) ➔Sickle-cell anaemia ➔Presence or history of prodromi of a thrombosis (e.g. transient ischaemic attack, angina pectoris). © The Swiss Pharmacy, Geneva Switzerland
  • 8. Diane-35 Tablets Contraindications ➔Presence of a severe or multiple risk factor(s) for venous or arterial thrombosis may also constitute a contraindication ➔Diabetes mellitus with vascular involvement. ➔Pancreatitis or a history thereof if associated with severe hypertriglyceridemia.Severe hepatic disease as long as liver function values have not returned to normal. Jaundice or persistent itching during a previous pregnancy, Dubin-Johnson syndrome, Rotor syndrome ➔History of deterioration of otosclerosis during pregnanacy. © The Swiss Pharmacy, Geneva Switzerland
  • 9. Diane-35 Tablets Contraindications ➔Presence or history of liver tumors (benign or malignant). ➔Known or suspected sex steroid influenced malignancies (e.g. of the genital organs or the breasts). ➔Undiagnosed vaginal bleeding. ➔Known or suspected pregnancy. ➔Disorders of lipid metabolism. ➔History of herpes gestationis. ➔Lactation. © The Swiss Pharmacy, Geneva Switzerland
  • 10. Diane-35 Tablets Side Effects of Diane-35 Pills The most frequent side effects include nausea, abdominal pain, weight increased, headache,depressed mood, mood altered, breast pain, and breast tenderness © The Swiss Pharmacy, Geneva Switzerland
  • 11. Diane-35 Tablets Warnings And Precautions ➔Circulatory Disorders:Epidemiological studies have suggested an association between the use of COCs and an increased risk of arterial and venous thrombotic and thromboembolic diseases such as myocardial infarction, stroke, deep venous thrombosis, and pulmonary embolism. These events occur rarely. ➔Tumors: Some epidemiological studies have indicated that long-term use of COCs may further contribute to increased risk of persistent HPV infection. © The Swiss Pharmacy, Geneva Switzerland
  • 12. Diane-35 Tablets Warnings And Precautions ➔Other conditions: Women with hypertriglyceridemia, or a family history thereof, may be at an increase risk of pancreatitis when using COCs. Crohn’s disease and ulcerative colitis have been associated with COC use. Chloasma may occasionally occur, especially in women with a history of chloasma gravidarum. ➔Pregnancy and Lactation: The administration of Diane- 35 is contraindicated during pregnancy. If pregnancy occurs during medication with Diane-35, the preparation is to be withdrawn immediately. The administration of Diane- 35 is also contraindicated during lactation. © The Swiss Pharmacy, Geneva Switzerland
  • 13. Diane-35 Tablets Overdose Symptoms There have been no reports of serious effects from overdose. Symptoms of overdose may include nausea, vomiting, or vaginal bleeding. In case of drug overdose, contact a doctor, hospital emergency department, or regional Poison Control Center immediately, even if there are no symptoms. © The Swiss Pharmacy, Geneva Switzerland
  • 14. Diane-35 Tablets Overdose Treatment There are no antidotes for Diane-35 overdose and further treatment should be symptomatic. © The Swiss Pharmacy, Geneva Switzerland
  • 15. Diane-35 Tablets Diane-35 Tablets Manufactured by Bayer Schering Pharma For more information click here © The Swiss Pharmacy, Geneva Switzerland