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House MD: Solving Complex IT
                       Issues Using Differential Diagnosis

                                   Steve Bennett

                            Steve@DaemonSolutions.com
                                  @DaemonSteve

Saturday, 30 June 12
AGENDA
                           A Brief History Of Medical Diagnosis.
                       Why & How You Should Prove Yourself Wrong.
                                   Differential Diagnosis.
                                 Diagnostic Approaches.
                                   Diagnostic Thresholds.
                                Do’s, Don’ts & Application.


Saturday, 30 June 12
Who’s This Guy?




Saturday, 30 June 12
Why...?




Saturday, 30 June 12
Saturday, 30 June 12
http://www.technologyreview.com/tr35/profile.aspx?TRID=1108




Saturday, 30 June 12
Saturday, 30 June 12
http://flic.kr/p/npaoT




Saturday, 30 June 12
http://4.bp.blogspot.com/_lSXhEtQUdtA/S-EL5w7dt3I/AAAAAAAAANE/G0oc_cGPXAY/s320/USAirways+in+the+water.jpg




Saturday, 30 June 12
Medical Diagnosis




Saturday, 30 June 12
http://4.bp.blogspot.com/-cCTr1WWve1E/TfefWAn8zvI/AAAAAAAAAA0/aXO50-syXuE/s1600/Imhotep_Museum-hd-1.jpg




                                  Imhotep - 2600BC
Saturday, 30 June 12
http://en.wikipedia.org/wiki/File:Edwin_Smith_Papyrus_v2.jpg




Saturday, 30 June 12
http://www.sculpturegallery.com/two/hippocrates3.jpg




                       Hippocrates - 460BC
Saturday, 30 June 12
http://www.sculpturegallery.com/two/hippocrates3.jpg




                           Galen - AD131
Saturday, 30 June 12
In Summary;
                       It’s Been Around A Long Time..




Saturday, 30 June 12
Hypothetico-Deductive Model




Saturday, 30 June 12
William Whewell




Saturday, 30 June 12
"No amount of experimentation can ever prove
                 me right; a single experiment can prove me
                                    wrong."
                                           Albert Einstein




Saturday, 30 June 12
Hypothetico-deductive model




Saturday, 30 June 12
Something unexplained happens.
Saturday, 30 June 12
http://www.flickr.com/photos/dougcaldwell/4213877479




                                                                             Hypothesize.




Saturday, 30 June 12
Plan a test that can falsify.
                            Predict the result.




Saturday, 30 June 12
Test.




                               http://www.flickr.com/photos/kenilio/3351824931


Saturday, 30 June 12
Hypothesize.
                       Plan a test that can falsify.
                                Predict.
                                  Test.



Saturday, 30 June 12
An Example.




Saturday, 30 June 12
I went shopping..




Saturday, 30 June 12
Saturday, 30 June 12
Saturday, 30 June 12
Failed Card
          http://flic.kr/p/9MShdE




Saturday, 30 June 12
Saturday, 30 June 12
Hypothetico-deductive model




Saturday, 30 June 12
Something unexplained happens.




Saturday, 30 June 12
Hypothesise.




Saturday, 30 June 12
I’ve Spent Too Much On SSD’s

                                                      My Wife Has Been Shopping




                                            Hypothesise.

                   There Is A System Problem


                                                       I Didn’t Pay My Bill In Time


Saturday, 30 June 12
Plan a test.
                         Predict.




Saturday, 30 June 12
Test: I’ll call the credit card company.



                                    Plan a test.
                                      Predict.




Saturday, 30 June 12
Test: I’ll call the credit card company.



                                    Plan a test.
                                      Predict.

                        Prediction: I have sufficient funds.

                        (If correct will falsify 3 hypothesis)

Saturday, 30 June 12
Test.




Saturday, 30 June 12
Test.

                       Result: I have sufficient funds.



Saturday, 30 June 12
I’ve Spent Too Much On SSD’s

                                                      My Wife Has Been Shopping




                                            Hypothesise.

                   There Is A System Problem


                                                       I Didn’t Pay My Bill In Time


Saturday, 30 June 12
Hypothesise.

                   There Is A System Problem




Saturday, 30 June 12
Hypothetico-Deductive Model

                                Hypothesise.
                        Plan a test that can falsify.
                                   Predict.
                                     Test.


Saturday, 30 June 12
Differential Diagnosis.




Saturday, 30 June 12
Or DDx




Saturday, 30 June 12
What is it?




Saturday, 30 June 12
It’s that thing that House does.




Saturday, 30 June 12
It's a framework for problem diagnosis.




Saturday, 30 June 12
It's best used alongside the
                       hypothetico-deductive model.




Saturday, 30 June 12
Process of elimination.




Saturday, 30 June 12
Assume most obvious.
                       Until proved otherwise.




Saturday, 30 June 12
"When you hear hoof beats, look for horses,
                                     not zebras"




Saturday, 30 June 12
Saturday, 30 June 12
Probability is your friend.




    http://www.flickr.com/photos/nashnosh/5922580484



Saturday, 30 June 12
Personalised probability is your best buddy.




                                                           http://www.flickr.com/photos/el5ajoola/3868649830

Saturday, 30 June 12
Here’s how it works.




Saturday, 30 June 12
Something happens.




Saturday, 30 June 12
Something bad happens.




Saturday, 30 June 12
Something bad and complicated happens.




Saturday, 30 June 12
Gather the facts...




Saturday, 30 June 12
Gather the facts...
                          Symptoms




Saturday, 30 June 12
Gather the facts...
                           Symptoms
                         Subject history
                       Previous test results
                 General observations


Saturday, 30 June 12
What else do we know?


Saturday, 30 June 12
http://www.flickr.com/photos/dougcaldwell/4213877479




                                                                             Hypothesise.




Saturday, 30 June 12
List Hypotheses.




Saturday, 30 June 12
Immediately discount.
                         Apply probability.




Saturday, 30 June 12
Prioritise hypothesis based on risk and
                                     probability.




Saturday, 30 June 12
Plan tests.
                       Predict results.




Saturday, 30 June 12
Test.
                       Or Treat.




Saturday, 30 June 12
Feedback results.




Saturday, 30 June 12
Continue until diagnosis is confirmed.




                                    http://www.o-min.com/wp-content/uploads/mobius1-300x225.jpg




Saturday, 30 June 12
Differential Diagnosis.

                         Gather the facts.
                          Hypothesise.
                         Apply Probability.
                            Prioritise.
                          Test or Treat.
                              Loop.

Saturday, 30 June 12
Diagnostic Approach




Saturday, 30 June 12
Possibilistic




Saturday, 30 June 12
Possibilistic
                       All Possibilities Are Equal

                            Test Everything




Saturday, 30 June 12
Possibilistic
                       All Possibilities Are Equal

                            Test Everything




Saturday, 30 June 12
Probablistic




Saturday, 30 June 12
Probablistic
                       Selection Based On Probability

                          Prioritise The Most Likely




Saturday, 30 June 12
Probablistic
                       Selection Based On Probability

                          Prioritise The Most Likely




Saturday, 30 June 12
Prognostic




Saturday, 30 June 12
Prognostic
                       Selection Based On Most Serious

                          Prioritise The Most Serious




Saturday, 30 June 12
Prognostic
                       Selection Based On Most Serious

                          Prioritise The Most Serious




Saturday, 30 June 12
Pragmatic




Saturday, 30 June 12
Pragmatic
                       Selection Based On Responsiveness To Treatment

                              Prioritise The Most Easily Treated




Saturday, 30 June 12
Pragmatic
                       Selection Based On Responsiveness To Treatment

                              Prioritise The Most Easily Treated




Saturday, 30 June 12
When do I use each approach..




Saturday, 30 June 12
Do something and do it fast...

                                Pragmatic.




Saturday, 30 June 12
If it really is that, we are in a world of hurt.

                                        Prognostic.




Saturday, 30 June 12
Default = Probabilistic.



Saturday, 30 June 12
I want more probability...




Saturday, 30 June 12
Pre & Post Test Probability.

           Current Probability: 30%

           If the result is X;
           There is 60% chance of hypothesis being correct.

           If the result is Y;
           There is 0% chance of hypothesis being correct.
Saturday, 30 June 12
This is easier in medicine.




Saturday, 30 June 12
! Differential Diagnosis...
                       ! Diagnostic Approach...




Saturday, 30 June 12
Diagnostic Thresholds




Saturday, 30 June 12
Define the point at which something is worth
                                     testing.




Saturday, 30 June 12
Probability of Diagnosis
                0%                                                        100%
                          Test                                Treatment
                       Threshold     High Priority Tests      Threshold




                  Not Worth                                        Worth
                   Testing              Worth Testing             Treating




Saturday, 30 June 12
Mnemonics.




Saturday, 30 June 12
Doctors Love Mnemonics.



Saturday, 30 June 12
Mnemonic for DDx.




Saturday, 30 June 12
Vascular
                       Idiopathic/Intoxication
                       Neoplastic
                       Degenerative/Deficiency
                       Inflammatory
                       Congenital
                       Autoimmune/Allergic
                       Traumatic
                       Endocrine


Saturday, 30 June 12
Mnemonic for Acute Pancreatitis.




Saturday, 30 June 12
GET SMASH’D
                       Gallstones
                       Ethanol
                       Trauma
                       Steroids
                       Mumps
                       Autoimmune
                       Scorpion bites
                       Hyperlipidemia
                       Drugs(azathioprine, diuretics)


Saturday, 30 June 12
Mnemonic for the web...




Saturday, 30 June 12
Users                         Operating system


                                                     Web server
                        Network

                       Cache/Code                Application engine

                                            Hardware
            Services (Third Party)   Database/Datastore
Saturday, 30 June 12
Cache/Code
                         Application engine
                         Services (Third Party)
                         Hardware
                         Web server
                         Operating system
                         Users
                         Network
                         Database/Datastore



Saturday, 30 June 12
                       CA$HWOUND
These are used to follow a path through trees.

Saturday, 30 June 12
C
                       A
                       $
                       H
                       W
                       O
                       U
                       N
                       D
Saturday, 30 June 12
How can this all help me?




Saturday, 30 June 12
It makes you more thorough.




Saturday, 30 June 12
It can help you fix things faster.




Saturday, 30 June 12
By working as a team.




Saturday, 30 June 12
By working more efficiently.




Saturday, 30 June 12
Reduces Thematic Vagabonding.




                                           http://www.flickr.com/photos/neloqua/166353267




Saturday, 30 June 12
Reduces Lone Wolf Heroism.




                                          http://www.flickr.com/photos/tambako/3559257456




Saturday, 30 June 12
Reduces Encystation




                                    http://www.flickr.com/photos/tambako/3559257456




                                                                                     http://www.flickr.com/photos/emmacoulston/4442688125


Saturday, 30 June 12
This is what it looks like.




Saturday, 30 June 12
Saturday, 30 June 12
I’ve run out of diagnosis.




Saturday, 30 June 12
You suck.
                          :-)




Saturday, 30 June 12
Then you’ve missed something.




Saturday, 30 June 12
Question your results, symptoms and
                                  observations.




Saturday, 30 June 12
Re-test if in doubt.




Saturday, 30 June 12
Call in a fresh pair of eyes.




Saturday, 30 June 12
Do’s and Don’ts




Saturday, 30 June 12
Assemble a team.




Saturday, 30 June 12
Get the right experts in the room.




Saturday, 30 June 12
Experts and generalists.




Saturday, 30 June 12
The diagnostic lead.

Saturday, 30 June 12
Diagnostic Lead, controls the pen.




   http://www.flickr.com/photos/scttw/1819085915

Saturday, 30 June 12
Take it in turns to lead.
Saturday, 30 June 12
Culture.




Saturday, 30 June 12
http://www.flickr.com/photos/41427839@N07/5973163369/




                                              Openness is key.


Saturday, 30 June 12
Encourage people to challenge.


Saturday, 30 June 12
And be challenged.

Saturday, 30 June 12
http://www.neale-wade.net/blog/wp-content/uploads/2008/08/100_1241.jpg




                       Collaborate.
Saturday, 30 June 12
Do not immediately dismiss ideas...




                                                       http://www.flickr.com/photos/albaflickr/4416770182/lightbox/



Saturday, 30 June 12
Do not immediately dismiss ideas...
                       that were not yours...



                                                       http://www.flickr.com/photos/albaflickr/4416770182/lightbox/



Saturday, 30 June 12
Do not immediately dismiss ideas...
                       that were not yours...
                          or your team’s...


                                                       http://www.flickr.com/photos/albaflickr/4416770182/lightbox/



Saturday, 30 June 12
http://www.flickr.com/photos/straubin/4541508733/




                 There is a time to debate and a time to act.




                                                                          http://www.flickr.com/photos/54182266@N02/5017666438

Saturday, 30 June 12
Get better at making group decisions.




Saturday, 30 June 12
Build a culture that encourages creative
                                      suggestions.




Saturday, 30 June 12
Practice makes perfect.




Saturday, 30 June 12
When do I use this..?




Saturday, 30 June 12
Complex Problems.




Saturday, 30 June 12
Active Problems.




Saturday, 30 June 12
Post Mortem




Saturday, 30 June 12
Conclusion




Saturday, 30 June 12
Try and prove yourself wrong.



Saturday, 30 June 12
DDx is a framework that YOU can use to
          resolve & manage your complex problems.
Saturday, 30 June 12
Be aware of the Diagnostic Approach that you
                  are using and why.




Saturday, 30 June 12
Create a
                       Mnemonic for
                       your system.

                        It acts as a
                         checklist.

Saturday, 30 June 12
Saturday, 30 June 12
Watch House.




Saturday, 30 June 12
Further Reading;
                                          The Process of Diagnosis (AMA) -
                       http://medicine.ucsf.edu/education/resed/articles/jama6_the_process.pdf


                              Jessie Robbins - Creating Resiliency Through Destruction-
                http://www.slideshare.net/jesserobbins/ameday-creating-resiliency-through-destruction

                                         All of John Allspaw’s presentations-
                                         http://www.slideshare.net/jallspaw

                                                     House MD
                                             http://www.fox.com/house/



Saturday, 30 June 12
Thank You.
                          :-)




Saturday, 30 June 12

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