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Interest in technology entrepreneurship aimed at solving the most intractable of global problems in the developing world is at an all-time high. A vast number of education programs, especially in engineering- and design-related degree programs, focus on developing appropriate technology solutions to Bottom of the Pyramid (BoP) challenges in sectors such as food, water, energy, health, education and global connectivity. For many years, funding organizations have underwritten such efforts, only to see successful technologies that ultimately failed in the adoption cycle. The global community has largely come to the conclusion that technologies often fail because of they were never turned into sustainable enterprises. The authors have significant experience creating ventures in a developing world context (Africa, Mexico, American Indian, etc.) and in developing for-credit and non-credit technology entrepreneurship curricula for sustainable development. This session will discuss their experiences and offer suggestions for implementing successful ventures and curricula.