Irio Calasso - Medirio, améliorer le traitement du diabète - e-health 6.6.14

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Irio Calasso - Medirio, améliorer le traitement du diabète - e-health 6.6.14

  1. 1. Medirio SA, Techno-Pôle 10, 3960 Sierre, Switzerland Journée E-Health Technoark a Sierre. June 6, 2014 E calasso@medirio.com M +41 79 820 20 86 Irio Calasso, PhD CEO
  2. 2. 95% OF PEOPLE ON INSULIN USE SYRINGES AND PENS PROS OF PENS • Cost efficient therapy compared to pumps • Misuse is limited CONS OF PENS • Several handling steps before and after injection • No discreetness • Injections are burdensome • No connectivity 5% DOCTORS PRESCRIBE PUMPS TO ONLY 5% OF PEOPLE ON INSULIN Medirio SA. June 6, 2014 Journée E-Health Slide 2.
  3. 3. HOW M-HEALTH CAN HELP IN THE DIABETES SUPPORTIVE CARE PROCESS Medirio SA. June 6, 2014 Journée E-Health Slide 3. • Track patient condition and behaviors • Advices and recommendations • Therapy regime adherence • Follow-up scheduling • Social peer-to-peer support • ..
  4. 4. Medirio SA. June 6, 2014 Journée E-Health Slide 4. J Med Internet Res 2014;16(4):e104 ANNUAL RELEASE FIGURES FOR DIABETES APPS
  5. 5. Medirio SA. June 6, 2014 Journée E-Health Slide 5. J Med Internet Res 2014;16(4):e104 MOBILE APPLICATIONS FOR DIABETES
  6. 6. Medirio SA. June 6, 2014 Journée E-Health Slide 6. To remove the stress related to each injection thank to an easy, simple to use and a supportive instrument. VISION
  7. 7. Medirio SA. June 6, 2014 Journée E-Health Slide 7. A. Disposable adhesive Patch B. Handheld device as user interface and controller / drive unit with connectivity OUR SOLUTION FOR THE PEN MARKET By placing the handheld device over the patch, the patch unlocks and receives energy to pump insulin even through the clothing. Aesthetic prototype
  8. 8. Medirio SA. June 6, 2014 Journée E-Health Slide 8. INSULIN DELIVERY A. The dose is selected on the handheld. B. To inject, the handheld is placed over the patch for 5 to 15 seconds. USABILITY To inject insulin, patients simply place the handheld over the patch. PREPARATION The disposable patch is attached to the body for 3 to 4 days.
  9. 9. Medirio SA. June 6, 2014 Journée E-Health IN THE DISPOSABLE PATCH • No battery • No electronics • No motors Low COG ( similar to insulin disposable pens ) . Small and easy to wear. IN THE HANDHELD • User interface • Driver and controller for the patch • Reminders and log-file • Blood glucose meter • Connectivity ENERGY TRANSFER FROM HANDHELD TO PATCH THE MAGIC BEHIND OUR TECHNOLOGY Slide 9.
  10. 10. Medirio SA. June 6, 2014 Journée E-Health Slide 10. COMPETITORS LANDSCAPE GREAT INJECTION EXPERIENCE AND ENHANCED USABILITY AT PEN COSTS Therapy cost 1500 Euro/year (95% of the market) Reimbursed in most countries 3500 Euro/year (5% of the market) Reimbursed mainly for type 1 OUR SYSTEM z
  11. 11. Medirio SA. June 6, 2014 Journée E-Health Slide 11. COMPLETE SYSTEM FOR A SIMPLE “PEN” TREATMENT Handheld with glucose meter
  12. 12. Medirio SA. June 6, 2014 Journée E-Health Slide 12. APPLICATIONS DATA EXCHANGE WIRELESS-ENABLED HANDHELD Connectivity is one of the services insulin pens cannot offer. Such service allows for data recording and sharing with doctors and relatives. This provides a powerful tool to improve treatment compliance.
  13. 13. Medirio SA. June 6, 2014 Journée E-Health Slide 13. APPLICATIONS DATA EXCHANGE USB- AND/OR BLUETOOTH-ENABLED HANDHELD While a wireless-enabled handheld would synchronise directly with the server, a USB/Bluetooth-enabled device connects to both mobile devices and personal computers which, in turn, will synchronise gathered data to and from the server.
  14. 14. Based on the exchange of + INSULIN DOSES + GLUCOSE LEVELS Future plans to include the process third parties data as: + FITNESS MAPPING + WEIGHT LOSS + HB1AC LEVELS + CARBOHYDRATE CONTENT OF FOOD Medirio SA. June 6, 2014 Journée E-Health Slide 14. INFORMED DECISIONS COMPREHENSIVELY INFORMED THERAPY DECISIONS
  15. 15. E-health – Improve therapy – Enabling disease management system – Reaching communities – Teaching communities – Enriching communities Journée E-Health Slide 15Medirio SA. June 6, 2014
  16. 16. Medirio SA, Techno-Pôle 10, 3960 Sierre, Switzerland or visit us at www.medirio.com Irio Calasso, PhD CEO E calasso@medirio.com M +41 79 820 20 86
  17. 17. BACKUPS Medirio SA. June 6, 2014 Journée E-Health Slide 17. Confidential
  18. 18. Medirio SA. June 6, 2014 Journée E-Health Slide 18. Confidential PATIENTS ACCEPTANCE GREAT ACCEPTANCE BY • People that start with the insulin therapy • Management of gestational diabetes (3-10% of pregnancies) • Children with diabetes (parents decide for the children) Very attractive also for established pen users (see slide “ADVANTAGES”) OR
  19. 19. Medirio SA. June 6, 2014 Journée E-Health Slide 19. Confidential ENHANCED INJECTION EXPERIENCE Easy, discreet and relaxed FAST TRAINING AND LEARNING Same therapy regime as for insulin pens REDUCED PRICKING Pricking amount and fear of injections are greatly reduced IDEAL PRODUCT for children, gestational diabetes and patients requiring multiple injections THERAPY TRACKING Log-files are produced to prove and improve therapy outcome CONNECTIVITY Passing data on to other devices broadens data-related services ADVANTAGES
  20. 20. Medirio SA. June 6, 2014 Journée E-Health Slide 20. Confidential FAQ TOPIC ANSWER NOTES Is the system safe and secure? Yes Doses, needle occlusion and empty reservoir are controlled and verified by the handheld device. Skin irritation due to the patch. Rarely Other products show low risk for irritation. The patch is attached to the body likewise as a pump infusion set. Waterproof patch device. Yes Showering and swimming allowed. ( a feature that has been demonstrated with similar products e.g. “Omnipod path pump” ) Does the needle hurts? Not at all The needle is a soft cannula as commonly used by pumps infusion set. Easily attached to body. Yes Few easy steps required. The patch is attached with an double-layer adhesive film. Insulin in the patch. TBD A. Patch device is prefilled with insulin; B. The patch is filled with insulin by the user just before usage ( as pump users do ).
  21. 21. Medirio SA. June 6, 2014 Journée E-Health Slide 21. Confidential MARKET INSTRUMENTS USED TO INJECT INSULIN 3.3 1 4.7 9.5 0.9 2 0 2 4 6 8 10 12 14 2008 2015 Users(millions) Syringe users Pen users Pump users OUR TARGET MARKET Market potential (in W-UE and USA only). 850 million disposable units/year ( Type 1 and Type 2 diabetes on insulin MDI )
  22. 22. CURRENT SITUATION Medirio SA. June 6, 2014 Journée E-Health Slide 22. Confidential Connectivity available no connectivity connectivity available 100 % use Lancing devices – Glucose meters 95% use Insulin pens & syringes People with diabetes (PWD) PWD on insulin 5% use insulin pumps

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