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  • 1. ACADEMIC UNIT OF SURGICAL ONCOLOGY RESEARCH ASSISTANT / ASSOCIATE REF: R3781 THE UNIVERSITY OF SHEFFIELD - INFORMATION FOR APPLICANTS The University of Sheffield, which celebrates its centenary in 2005, is one of the UK’s leading universities, with an international reputation for excellence in both teaching and research. Excellence in research In constantly developing the quality and diversity of its research across a wide range of subjects, the University has appointed many outstanding academics to its multidisciplinary research groups. In the most recent national Research Assessment Exercise, 35 subject areas achieved the top two grades, 5* and 5 – only five other universities exceeded that number. Our annual income for pure and applied research is fast approaching £100 million. Sheffield University Enterprises Ltd (SUEL), a wholly owned technology transfer subsidiary, has a portfolio of more than 70 projects developed out of University of Sheffield research, and more than 40 companies have already been founded. For example, one of these spin-out companies, CellTran Ltd, recently launched its pioneering biological bandage, Myskin, for treating patients suffering from severe burns. Excellence in learning and teaching The University maintains high standards in its undergraduate programmes. In the national Quality Assurance Agency’s Subject Reviews, the University has earned ‘excellent’ ratings in 29 subjects – the third highest number among all UK universities. The QAA’s institutional audit report on the University places it in the best of the three categories – “broad confidence” – in both the management of the quality of its academic programmes and the academic standards of its awards. Strategic alliances The University of Sheffield is a founder member of two major alliances. The Worldwide Universities Network is a consortium of 16 research-led universities in the UK, mainland Europe, USA and China. It exists to capitalise on growing global markets in research, postgraduate degree programmes and continuing professional development. The White Rose Consortium of Leeds, Sheffield and York universities 1
  • 2. exploits the combined research power of the three institutions and invests in spin- out companies. International and national honours In the 1990s two of our graduates won Nobel Prizes – Dr Richard Roberts for Medicine/Physiology in 1993 and Professor Sir Harry Kroto for Chemistry in 1996. Three other Nobel Laureates are associated with the University: Lord Florey (Medicine/Physiology, 1945), Professor Sir Hans Krebs (Medicine/Physiology, 1953) and Lord Porter (Chemistry, 1967). Since 1998 three Queen’s Anniversary Prizes, academic equivalents to the Queen’s Award for Enterprise, have recognised the University’s pioneering work – in creating definitive electronic editions of major literary texts, in environmental consultancy for industry and government, and in research into improving the health and social care of older people. Campus, students and staff The University received its Royal Charter in 1905, although its roots go back to 1828, when the Sheffield School of Medicine was founded. The academic buildings – a mixture of Edwardian and modern – are set in pleasant suburbs in the west of Sheffield, close to the Peak District National Park yet within easy reach of the city centre. A five-year £100 million building programme is providing new and refurbished accommodation for many departments, as well as state-of-the-art sports facilities. We are investing £16 million in a new learning resources centre to provide an advanced integrated learning environment for our students. There are 25,000 full-time and part-time students studying in the University, of whom 19,450 are undergraduates and 5,550 postgraduates. Included in this figure are more than 3,846 international students from 116 countries. Working for the University The University has an ambitious HR strategy and recognises that its success depends upon recruiting, rewarding and developing high-quality staff in all areas. We are Sheffield’s third largest employer, with 6,000 staff working in a wide range of jobs, and we are proud to recognise that our success is due to the personal contribution made by all our staff. Working at the University will offer you exciting and rewarding opportunities within a dynamic and diverse workplace. The City of Sheffield Sheffield offers outstanding quality of life, an attractive, green environment, affordable living costs, excellent schools, short travel-to-work times, leading NHS care and a wide choice of housing. According to the latest Home Office crime statistics, Sheffield is England’s safest city. A recent Barclay’s survey revealed that Sheffield Hallam, the parliamentary constituency which includes much of our campus, is the second most affluent in England in real terms. 2
  • 3. As you would expect in England’s fourth largest city, there is a wealth of leisure, entertainment, sports and recreational opportunities to suit all ages, tastes and abilities. What the neutrals say In the 2005 Times Good University Guide twenty of our departments hold top-ten positions in the subject league tables, which are based on teaching and research quality, entry qualifications and graduate destination data. In the Virgin 2005 Alternative Guide to British Universities, which focuses strongly on the quality of the student experience, the University of Sheffield is rated very highly: ”Sheffield is a top university across the board. Whichever one of our statistical boxes you care to consult – Where Sheffield Graduates End Up, Academic Excellence, What It’s Really Like – they excel.” Further information on the above areas is also available at www.sheffield.ac.uk/jobs and www.sheffield.ac.uk/about THE SCHOOL OF MEDICINE AND BIOMEDICAL SCIENCES The Medical School, although physically located at the Royal Hallamshire Hospital site, also has Divisions/Sections based in the other hospitals in the city, in particular at the Northern General Hospital, and also at three specialist hospitals – Sheffield Children’s Hospital, the Jessop Wing and Weston Park Cancer Hospital. Currently, the Medical School has 190 academic staff and an annual intake of 250 students to the MBChB course (UCAS A106). The School was graded at 5 in the last Research Assessment Exercise. The administrative structure within the Medical School brings together a wide range of disciplines, grouped into three Academic Divisions, each with an executive director. The infrastructure of the School of Medicine is currently undergoing a major refurbishment (funded by the Wellcome Trust and the University of Sheffield) to provide up to date facilities for basic and clinical research centred on the Royal Hallamshire Hospital site. Biomedical Science is located in the Western Bank complex that houses the School of Biology, which also includes the Departments of Molecular Biology & Biotechnology and Animal and Plant Sciences. The total staff in the Department is currently in excess of 150 including about 35 academic staff together with technicians, postdoctoral research fellows and postgraduate students. The curriculum of the MBChB course integrates clinical medicine and medical sciences throughout all years. Both academic staff and NHS clinicians teach and assess students. Such staff also provide opportunities for students to undertake intercalated Bachelor of Medical Sciences courses and offer briefer research attachments lasting a few weeks. DIVISION OF CLINICAL SCIENCES (SOUTH) The Division encompasses a broad range of disciplines with strong research activities in both basic science and clinical areas. Throughout the Academic Units, our goal is to apply basic science in clinical research. The Division is responsible for providing a substantial clinical service together with the teaching of undergraduate and postgraduate students. 3
  • 4. The total staff in the Division is in excess of 250 which includes a mix of academic, clinical academic, postdoctoral and graduate researchers, secretarial and technical support. In addition, we have over 50 registered PhD students and 40 MD students, together with masters and undergraduate students on taught courses. The Division has strong research groups, of both national and international standing, in both basic and clinical areas. Academic Units include Anaesthesia, Child Health, Clinical Pharmacology, Ophthalmology and Orthoptics, Radiology, Reproductive Medicine, Sports Medicine, Supportive Medicine, Surgical Oncology and Urology. Research in the Division is funded by the MRC, NCRI, Wellcome Trust, Department of Health, YCR, CRUK and other funders through programme and project grants. DIVISION OF CLINICAL SCIENCES (NORTH) The Division of Clinical Sciences (North) is based at the Northern General Hospital and is due to be relocated at the Royal Hallamshire Hospital site in April 2006. It incorporates the Sections of Cardiovascular Science and Human Metabolism. Academic Units include: cardiovascular, immunobiology, vascular, bone metabolism, human nutrition, nephrology, skin research and diabetes & endocrinology. A wide variety of funding for basic science and clinical research has been secured in the form of programme grants, project grants, studentships and fellowships from the Arthritis Research Campaign, BBSRC, BDA, British Heart Foundation, FSA, Heart Research UK, NKRF, Medical Research Council, SAKA, SKRF, Wellcome Trust as well as funding from a number of commercial companies. The total number of staff and students in the Division is in excess of 180 which includes academic, clinical academic, postdoctoral research fellows, research assistants/associates, technical and secretarial staff. There are over 100 postgraduate students registered for PhD/MPhil and MD courses in addition to undergraduate and masters students. DIVISION OF GENOMIC MEDICINE The Division comprises three sections of Genetics and Informatics, Functional Genomics and Oncology and Pathology including Forensic Pathology. The Division was formed from the amalgamation of Molecular and Genetic Medicine, Cancer Studies, Human Metabolism and Clinical Biochemistry, Pathology, Forensic Pathology and Clinical Oncology. The Division of Genomic Medicine provides clinical services in: Medical Oncology; Haematology; Respiratory Medicine; Rheumatology; Infectious Diseases; Dermatology; Neurology; Psychiatry; Pathology (including Forensic Pathology and Neuropathology) and Microbiology. There are strong research programmes in fundamental and clinical aspects of these branches of Medicine, including MRC Co-op, Wellcome Trust, ARC, YCR and industrial supported groups. The Division comprises of 400 members of staff and postgraduate students. RESEARCH IN THE SCHOOL OF MEDICINE & BIOMEDICAL SCIENCES This is currently grouped into six research themes. Cancer Research Theme Cancer research in Sheffield has well-established programs in both basic and clinical research. The basic research program is based in the Institute for Cancer 4
  • 5. Studies, which occupies 800 sq. metres of newly refurbished space on the top floor of the Medical School. As well as research space for seven investigators, the Institute provides core facilities for cancer researchers throughout Sheffield. These facilities include fluorescent activated cell sorting (FACS), DNA sequencing, high throughput DNA sample processing, confocal and time-lapse microscopy, and a radiation source. The Academic Unit of Clinical Oncology is located in the Cancer Research Centre (CRC), a purpose built clinical trials facility at the Weston Park Hospital. The CRC provides facilities for the assessment and treatment of patients, office space for staff with fully networked computer systems, and specialist facilities including laboratory space and bone densitometry. The North Trent Cancer Research Network (NTCRN) is co-ordinated from the CRC. Cardiovascular Research Theme The theme comprises strong groups working in basic and clinical science. These groups are the Cardiovascular Research Group, the Academic Unit of Haematology, the Academic Unit of Anaesthesia, the Academic Unit of Clinical Pharmacology and the Academic Unit of Medical Physics and Clinical Engineering (cardiovascular group). The theme covers genetic, cellular and clinical research in cardiovascular medicine. Main areas are coronary artery disease, cardiovascular pharmacology, the microcirculation, haemostasis and thrombosis, and cardiovascular modelling. This group currently has programme grant funding from the British Heart Foundation (BHF), a number of project grants as well as an MRC Establishment Grant, Clinical Training Fellowships from the MRC and Wellcome Trust funding. The Haemostasis and Thrombosis group at the Royal Hallamshire Hospital has established international status including co-ordinator status for EU FP5 project funding, and additional funding from Wellcome and BHF. The group within Medical Physics has similar European and international collaborations with significant associated grant funding (CEC, FP5, EPSRC). Endocrinology and Reproduction Research Theme The strength of the Endocrinology and Reproduction research theme is in translational research; from the laboratory to the patient and from clinical research to service delivery. Hormones regulate both single cell and whole body metabolism and the study of hormones and cell biology underpins the Endocrinology and Reproduction research theme. Stem cells provide great promise and the Jessop Wing with its integrated assisted conception unit and HFEA approved research laboratories provides the ideal infrastructure for collecting, developing and applying stem cell technology. The innovative nature of Endocrinology Research theme basic research is illustrated by the successful formation of two spinout companies one developing stem cells, Axordia Ltd, and the other cytokine receptor modulators, Asterion Ltd. Diabetes and thyroid disease are the commonest endocrine conditions each affecting up to 5% of the population. The identification of antigens in autoimmune endocrine disorders is a major focus of the Endocrinology and Reproduction research theme. The University of Sheffield Diabetes group has been instrumental in changing UK clinical practice with the introduction of new methods for empowering patients, the DAFNE project, and investigating the commonest complication of diabetes, hypoglycaemia in both Type 1 and Type 2 diabetes. The Endocrinology and Reproduction research theme has particular strengths in Clinical Research with the UK’s largest integrated endocrine unit allowing the development of specialised clinics with a particular emphasis on pituitary disease and transitional care of paediatric patients. The groups in the Endocrinology and Reproduction theme include: Diabetes, Endocrine Autoimmunity, Neuroendocrinology, Paediatric 5
  • 6. Endocrinology, Reproduction and are located in Clinical Sciences (North), The Jessop Wing, and The Children’s Hospital. Infection, Inflammation and Immunity Research Theme The 3Is research theme incorporates basic science groups working in molecular cell biology with clinical specialities including respiratory medicine, infectious diseases, rheumatology and dermatology. This grouping received a 5* rating from the 2001 RAE Infection and Immunity sub-panel. There is a substantial base of Wellcome Trust funding, together with MRC and BHF support. There are 2 clinician scientists (1 Wellcome Trust, 1 MRC) and an MRC Co-operative Group “Mechanisms of Cytokine Action in Chronic Inflammation.” Although the majority of theme members are within the Division of Genomic Medicine, there are important contributions from Biomedical Sciences, Endocrinology and others. Musculoskeletal Research Theme The Musculoskeletal research theme comprises groups working in both basic and clinical science. These groups include the Bone Metabolism Group, the Bone Biology Group, the Childrens Bone Disease Group and the Academic Rheumatology Group. Research activity within the theme includes genetic, cellular, molecular and clinical research into common musculoskeletal disorders. The main areas of research are in bone physiology and the metabolic bone diseases, such as osteoporosis, childhood bone disease including osteogenesis imperfecta, in the bone oncology area, particularly in tumour induced bone diseases such as multiple myeloma, and metastatic bone disease, and in the rheumatic diseases. There is substantial cross theme cooperation, for example collaboration with members of Cancer theme in the bone oncology area is a major strength. Research activity within the Musculoskeletal research theme is supported through a broad portfolio of research funding. This includes project and programme grant support from major U.K. funding organizations such as the Medical Research Council, the Arthritis Research Council, BBSRC and the Leukaemia Research Fund. Substantial support from biotechnology and pharmaceutical companies has formed the basis for significant translational and clinical research programmes. A major emphasis of the Musculoskeletal theme is in career development. This has been demonstrated by the success of members of the theme in attaining personal support through Fellowship schemes, which include Arthritis Research Council Clinician Scientist and Clinical Research Fellowship awards. Neurosciences Research Theme Clinical Neurosciences research in Sheffield has been strengthened by recent strategic investments in Neurology, Neuropathology and Biological Psychiatry. This development is based on common research interests in neurodegenerative diseases (diseases of the motor system, basal ganglia and dementia) and neuropsychiatric disorders (psychosis and major affective disorders). We are strategically placed to combine interdisciplinary methodologies from animal and cell models, access to populations across South Yorkshire in human genetic, structural and functional neuroimaging studies, and to develop and investigate novel pharmacological, surgical and psychological interventions. There are 3 main research groupings: Neurology/Neuropathology; Biological Psychiatry; and Neuroimaging. There are other areas of strong Neuroscience research within the University of Sheffield. These include Cellular and Molecular Neuroscience groupings within the two main component institutes of Biological Sciences (Institute of Molecular Physiology and Centre for Development Genetics) whose main strengths are in 6
  • 7. developmental neuroscience, and the role of P2X receptors and extracellular signalling by ATP, and sensory signal transduction. There are also strong groupings in Cognitive Neuroscience in the department of Psychology including: structure and function of the basal ganglia and related circuits; drug dependence; reparative strategies in retinal degeneration; functional imaging; psychopharmacology, Medical Physics, Human Communication Sciences. SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST Sheffield Teaching Hospitals became one of the first NHS Foundation Trusts on July 1st 2004, and manages five major hospitals in Sheffield – the Northern General, Royal Hallamshire, Jessop Wing, Weston Park and Charles Clifford Hospitals, making it the second largest NHS Trust in England. As a Trust, Sheffield Teaching Hospitals is responsible for the planning and delivery of the highest quality patient care, providing services for patients not only from Sheffield but all parts of the UK. The annual budget is approaching £520 million, with almost one million patients each year. Further details are included in the attached document ‘Profile of Sheffield Teaching Hospitals NHS Foundation Trust’. POST DETAILS JOB TITLE: Research Assistant / Associate BACKGROUND TO POST: This is a Cancer Research UK funded position to support research into the therapeutic targeting of tumour vasculature. Further details are available at http://www.shef.ac.uk/dcss/medical/surgical-oncology/research/tmg.html BRIEF OUTLINE: Based within the Tumour Microcirculation Group, this post is part of an ongoing Cancer Research UK programme of research to target the established tumour vasculature for cancer therapy. The post is available on a fixed- term basis until September 2008, in the first instance, with the possibility of further renewal subject to funding. The Research Assistant / Associate will support in vivo research into the therapeutic targeting of tumour vasculature. Duties will include carrying out laboratory-based experiments and operating imaging equipment. Applicants should have a relevant BTEC or BSc for the Research Assistant post and a PhD for the Research Associate post., Applicants should be technically proficient and have excellent organisational, communication and team-working skills. RELEVANT PUBLICATIONS: Tozer, G.M., Kanthou, C. and Baguley, B. C., 2005, Disrupting tumour blood vessels: combretastatins, DMXAA and other low molecular weight drugs, Nature Reviews Cancer, 5: 423-435 (2005). Cemazar, M., Wilson, I., Prise, V. E., Bell, K. M., Hill, s. A. and Tozer, G. M. The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification Br J Cancer, 93: 98-106 (2005). Tozer, G.M., Ameer-Beg, S.M., Baker, J., Barber, P.R., Hill, S.A., Hodgkiss, R.J., Locke, R.J., Prise, V.E., Wilson, I. and Vojnovic, B. Intravital imaging of tumour vascular networks using multi-photon fluorescence microscopy. Adv Drug Deliv Rev, 57: 135-152 (2005). 7
  • 8. Sonveaux, P., Kaz, A. M., Snyder, S. A., Richardson, R. A., Cardenas-Navia, L. I., Braun, R. D., Pawloski J. R., Tozer, G. M., Bonaventura, J., McMahon, T. J., Stamler, J. S., Dewhirst, M. W. Oxygen regulation of tumor perfusion by S- nitrosohemoglobin reveals a pressor activity of nitric oxide. Circ Res, 96:1119- 1126 (2005). Tupper, J., Greco, O., Tozer, G. M. and Dachs, G. U. Analysis of the horseradish peroxidase / indole-3-acetic acid combination in a three dimensional tumour model. Cancer Gene Therapy, 11: 508-513 (2004). Tozer, G. M. and Bicknell, R. Therapeutic Targeting of the Tumour Vasculature, Semin. Radiat. Oncol., Semin Radiat Oncol, 14: 222-232 (2004). Kanthou, C., Greco, O., Stratford, A., Cook, I., Knight, R., Benzakour, O. and Tozer, G. The tubulin-binding agent combretastatin A-4-phosphate arrests endothelial cells in mitosis and induces mitotic cell death. Am J Pathol, 165: 1401-1411 (2004). Galbraith, S. M., Maxwell, R. J., Lodge, M. A., Tozer, G. M., Wilson, J., Taylor, N. J., Stirling, J., Sena, L., Padhani, A. R. and Rustin, G. J. S. Combretastatin A4 phosphate has tumour antivascular activity in rat and man, as demonstrated by dynamic magnetic resonance imaging. J Clin Oncol. 21: 2831-2842 (2003). Tozer, G. M., Kanthou, C., Parkins, C. S. and Hill, S. A. The biology of the combretastatins as tumour vascular targeting agents. Int. J. Exp. Pathol., 83: 21-38 (2002). Prise, V.E., Honess, D.J., Stratford, M.R.L., Wilson, J. and Tozer, G.M. The vascular response of tumour and normal tissues in the rat to the vascular targeting agent, combretastation-A4-phosphate, at clinically relevant doses, Int J Oncol, 21: 717-726 (2002). Kanthou, C. and Tozer, G.M. The tumour vascular targeting agent Combretastatin A-4-Phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells. Blood, 99: 2060-2069 (2002). Hill, S.A., Chaplin, D.J., Lewis, G. and Tozer, G.M. Schedule dependence of combretastatin A4 phosphate in transplanted and spontaneous tumour models, Int J Cancer, 102: 70-74 (2002). Greco, O., Dachs,G.U., Tozer, G.M. and Kanthou, C. Mechanisms of cytotoxicity induced by horseradish peroxidase / indole-3-acetic acid gene therapy. Journal of Cell Biochem, 87: 221-232 (2002).Tozer, G. M., Prise, V. E., Wilson, J., Cemazar, M., Shan, S., Dewhirst, M. W., Barber, P. R., Vojnovic, B. and Chaplin, D. J. Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Research; 61; 6413-6422 (2001). MAIN ACTIVITIES & RESPONSIBILITIES: The general aim of the research programme is to develop new and existing methods for therapeutic targeting of the tumour vasculature. The post holder will contribute to several related in vivo projects, reporting to post-doctoral scientists on a day-to-day basis, and will carry out other duties, as determined by the group head. Duties will include: • setting up microsurgical preparations • operating imaging equipment • carrying out biochemical and therapeutic response assays • analysing expression of genes and proteins in excised tissues • record-keeping • contributing to data analysis and presentations • contributing to general laboratory maintenance 8
  • 9. • administrative tasks associated with ensuring compliance with safety and other procedures. Full training will be given, where necessary. PERSON SPECIFICATION (E: Essential, D: Desirable) The person we are looking for will be an enthusiastic biologist or cancer researcher with an interest in increasing their knowledge and skills in tumour vascular science research. Qualifications • BSc or BTEC (E) • A PhD will be required for appointment as a Research Associate (E) Experience/Abilities • Enthusiasm for physiological/ pathophysiological research (E) • Excellent record-keeping skills (E) • Good organisational skills (E) • Aptitude for intricate work (E) • Ability to operate complex electronic equipment (E) • Good writing and numeracy skills (E) • Ability to work independently when required (E) • Willingness to learn new skills (E). • Evidence of contribution to publications of good quality research articles (D) • Experience of laboratory work (D) • Background in physiology and/or biochemistry (D) • Computer skills (D) Inter-personal skills • Team player (E) • Strong communication skills (E) FURTHER INFORMATION INFORMAL ENQUIRIES: Candidates should contact Professor G. Tozer, (+44 (0)114 271 2423), G.Tozer @sheffield.ac.uk). SALARY: £19,645 - £28,850 per annum, with the potential to progress to £31,544 upon demonstration of sustained exceptional contribution. TERMS AND CONDITIONS OF EMPLOYMENT: Will be those for grade 7 staff, a summary version is attached for information only. Please note that the terms and conditions for all appointments are currently being reviewed as part of the implementation of the University of Sheffield Grading Scheme. New appointees will be provided with the final version on appointment. BENEFITS FOR STAFF In addition to competitive pay and generous holiday entitlements, our staff enjoy access to: 9
  • 10. • final salary pension scheme • corporate Childcare Vouchers scheme • Home Computing Initiative scheme: www.sheffield.ac.uk/hci • special staff rates for S10 Health membership: www.sheffield.ac.uk/s10/index.html • outstanding sports and recreational facilities. CLOSING DATE: 17 November 2005. PLEASE QUOTE REFERENCE NO: R3781 HOW TO APPLY: Online: Please visit www.sheffield.ac.uk/jobs, click on the title of the post you wish to apply for and select the 'apply online' link. Or please send: a) your full curriculum vitae with a covering letter explaining your interest in, and suitability for, this vacancy (two copies of each) b) a completed Summary Information Form/Equal Opportunities Monitoring Form by post to: The Staff Recruitment Service Department of Human Resources The University of Sheffield Firth Court Western Bank SHEFFIELD S10 2TN or in person to: The Staff Recruitment Service Department of Human Resources The University of Sheffield 10 - 12 Brunswick Street SHEFFIELD S10 2FN (Reception is open Monday-Friday 9am - 5pm). CIRCULATION OF APPLICATIONS As part of the selection process, applications may be considered by a number of appropriate staff within the recruiting department, and a cognate department, in addition to the shortlisting/interview panel(s). Please state within your covering letter if you do not wish your application to be released in this manner, or whether you would prefer it to be circulated on a restricted basis, e.g. as an anonymous CV. INTERVIEW EXPENSES Candidates attending for interview will be provided with the appropriate claim form. The University will defray standard return rail fare and reasonable subsistence expenses. Claims for car mileage are accepted when it is agreed in advance that rail travel is not a practicable alternative. Arrangement for travel from outside the UK must be made with the recruiting department in advance of the interview. To meet Inland Revenue requirements, expense claims must be accompanied by original receipts. 10
  • 11. 11
  • 12. WORK PERMITS If an applicant selected to be appointed requires a work permit to work in the UK, the University may issue a conditional offer of employment subject to a successful work permit application. The Home Office is the Government department charged with the responsibility of issuing work permits. It has in place strict criteria regarding eligibility and work permits will only be issued for posts where it can be demonstrated that there is a skills shortage which cannot be met from within the European Economic Area. Where it is reasonable to assume that there is an appropriate recruitment market within the EEA, it is unlikely that a work permit will be issued. Therefore certain types of post are unlikely to be considered eligible for a work permit. Further information is available on the Home Office website at: http://www.workingintheuk.gov.uk/. The persons whom the University considers may not be limited to those who make applications in accordance with the current advertisement. The University is committed to equality through diversity 12
  • 13. SUMMARY OF KEY TERMS AND CONDITIONS FOR APPLICANTS FOR INFORMATION ONLY The agreed and negotiated revisions to terms and conditions will include: Grades 1 and 2 • Hours of Work: 37 per week. • Overtime: Up to 40 hours, paid at time. Over 40 hours paid at time and a half. • Annual Leave: 27 days, plus 3 closure days, plus 8 Bank Holidays. • Pension scheme: The University of Sheffield Pension Scheme. Grades 3, 4 and 5 • Hours of Work: 35 per week. • Overtime: Up to 40 hours, paid at time. Over 40 hours paid at time and a half. • Annual Leave: 27 days, plus 3 closure days, plus 8 Bank Holidays. • Pension scheme: The University of Sheffield Pension Scheme. Grade 6 • Hours of Work: 35 per week. • Overtime: Up to 40 hours, paid at time. Over 40 hours paid at time and a half. • Annual Leave: 27 days, plus 3 closure days, plus 8 Bank Holidays. • Pension scheme: The Universities Superannuation Scheme. Grades 7, 8 and 9 • Hours of Work: Nominal 35 per week. • Overtime: Not applicable. • Annual Leave: 30 days, plus 3 closure days, plus 8 Bank Holidays. • Pension scheme: The Universities Superannuation Scheme. Sick pay entitlement is the same for all grades: Full Pay Half Pay Year 1 – first 3 months 2 weeks 2 weeks Year 1 – after 3 months 2 months 2 months Years 2 and 3 3 months 3 months Years 4 and 5 5 months 5 months After 5 Years 6 months 6 months Notes • These terms and conditions will come into effect, wherever practicable, from 1 October 2005. • Part time hours and leave will be pro rata. • Individual working patterns will be agreed in order to meet local business needs; no changes will be made to existing working patterns without individual agreement. 13
  • 14. • All paid overtime must be agreed in advance and may be taken as time- worked off in lieu. • All staff in Grades 1 to 6 will have 5 agreed days of work (for most staff these will be Monday to Friday) and all hours up to 40 worked within this standard working week will be paid at plain time; any hours over 40 will be paid at time and a half. Any hours worked on days 6 and 7 will be paid at premium rates. • Closure days will be agreed by Council each year and will normally be expected to lie between Christmas and New Year. 14
  • 15. Premium rates A number of premium rates will apply for staff in Grades 1 to 6: • x 1.3 for work between 10.00 pm and 6.00 am • x 1.5 for all hours worked on the 6th worked day of the week • x 2 for all hours worked on the 7th worked day of the week • x 2 for all hours worked on University Closure Days • x 2 for all hours worked on Bank Holidays (plus time-worked off in lieu). Existing allowances will continue for alternating and rotating shifts. Call out An appropriate mechanism will be available to reward staff on all grades who are, on a regular basis, on call and are subject to ‘call out’ to perform duties out of normal working hours. Pensions All new staff will be eligible to join the appropriate pension scheme for their grade. 15