CURRICULUM VITAE

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CURRICULUM VITAE

  1. 1. CURRICULUM VITAE NAME: Benedict B. Benigno, M.D. LOCATIONS: Southeastern Gynecologic Oncology, LLC 980 Johnson Ferry Road, #900 Atlanta, GA 30342 BIRTHDATE: July 7, 1938 BIRTHPLACE: New York, New York EDUCATION: 1960 B.S. Iona College New Rochelle, New York 1964 M.D. Georgetown University 1964 – 1965 Rotating Internship – Obstetrics/Gynecology St. Vincent’s Hospital and Medical Center New York, New York 1969 – 1970 Fellow in Gynecologic Oncology Emory University Atlanta, Georgia 1970 – 1973 Visiting Professor University of Saigon South Vietnam 1973 – 1974 Fellow in Gynecologic Oncology M.D. Anderson Hospital Houston, Texas LANGUAGES: English (Primary), Fluent French (Secondary) LICENSURE: New York, 1965 – Inactive Georgia, 1974 – Active Benedict B. Benigno, M.D. Page 1 of 13 Revised: 1/29/2015
  2. 2. CERTIFICATION: American Board of Obstetrics and Gynecology, November 12, 1971 Subspecialty Certification in Gynecologic Oncology, February 15, 1979 PROFESSIONAL APPOINTMENT: 1974- 1978 Assistant Professor, Obstetrics/Gynecology Emory University – School of Medicine Atlanta, Georgia October 1978 – Associate Professor, Obstetrics/Gynecology June 1982 Emory University – School of Medicine Atlanta, Georgia June 1982 Clinical Associate Professor, Obstetrics/Gynecology Emory University – School of Medicine Atlanta, Georgia 1997 – Present Director of Gynecologic Oncology Northside Hospital Atlanta, Georgia PRIVATE PRACTICE: 1982 – 1988 Benedict B. Benigno, M.D. 993-F Johnson Ferry Road Suite 300 Atlanta, Georgia 1989 – Present Founder and President Southeastern Gynecologic Oncology, LLC 980 Johnson Ferry Road Suite 900 Atlanta, Georgia 1999 – Present Founder and Chief Executive Officer The Ovarian Cancer Institute Georgia Institute of Technology Administration Building 225 North Avenue – 4th Floor Atlanta, Georgia 30332 Benedict B. Benigno, M.D. Page 2 of 13 Revised: 1/29/2015
  3. 3. MEDICAL AND SCIENTIFIC SOCIETY MEMBERSHIPS: Alpha Omega Alpha – Honor Medical Society (2003) American Association for Cancer Research (2006) American Board of Obstetrics and Gynecology American Medical Association American Radium Society American Society of Clinical Oncology Atlanta Obstetrical and Gynecological Society Biomedical and Health Sciences Institute at University of Georgia, Affiliate Member (2003) Clinical Oncology Association of Georgia Emory University of Medicine – Clinical Associate Professor of Gynecologic Oncology European Society of Gynaecological Oncology (2005) Felix Rutledge Society Georgia State Obstetrical and Gynecological Society Georgia Surgical Society Gynecological Laser Society International Gynecologic Cancer Society Medical Association of Atlanta Parker H. Petit – Institute for Bioengineering and Bioscience, External Advisory Board Society of Gynecologic Oncologists Southern Medical Association South Atlantic Association of Obstetricians and Gynecologists Benedict B. Benigno, M.D. Page 3 of 13 Revised: 1/29/2015
  4. 4. HONORS: Alpha Omega Alpha Honorary Medical Society Emory University, 1978 Hero’s of Medicine Award (2002) – “Most Innovative Cancer Research in Georgia” GRANTS: Comparative Study of Piperacillin Sodium (PIPRACIL) and Cephalothin Sodium (KEFLIN) for Prophalaxis in Patients Undergoing Vaginal Hysterectomy. Lederle Laboratories. Comparative Study of Piperacillin Sodium (PIPRACIL) and Cefoxitin Sodium (MEFOXIN) for Prophalaxis in Patients Undergoing Cesarean Section. Lederle Laboratories. A Randomized Comparison of the Efficacy of Cefoxitin versus Combination Therapy with Clindamycin and Gentamicin in the Treatment of Infection of the Female Genital Tract. Merck Sharp and Dohme Research Laboratories. A Study Evaluating the Accuracy of the Thermascan Device in Women with a Suspected Breast Malignancy Ultimately Confirmed by Biopsy. BCD Products, Inc. An Efficacy Trial of the Thermascan Device in Women with a Breast Mass to be Biopsy-Evaluated. Ortho Pharmeceutical Corporation. Multi-Center, Open, Comparative Study of Intravenous Cefotetan and Cefoxitin as Prophylactic Agents in Cesarean Section. Stuart Pharmaceuticals. Randomized Comparison of Two Regimens as First Line Chemotherapy for Advanced Breast Cancer: Cyclophosphamide – Novantrone – 5 – Fluorouracil versus Cyclophosphamide – Adriamyacin – 5 – Fluorouracil. Lederle Laboratories. A Double-Blind, Comparative, Multi-Center Study of the Safety and Efficacy of Cefixime versus Amoxicillin in the Treatment of Acute Urinary Tract Infections. Lederle Laboratories. Benedict B. Benigno, M.D. Page 4 of 13 Revised: 1/29/2015
  5. 5. GRANTS (CONT.): Multi-Center, Open, Comparative Study of Intravenous Cefotetan One Gram and Mefoxin as Prophylactic Agents in Women Undergoing Vaginal or Abdominal Hysterectomy. Stuart Pharmaceuticals. Comparitive Efficacy and Safety of a Combination of Epirubicin Plus Cisplatin versus Cisplatin Alone in the Treatment of Advanced Carcinoma of the Ovary: A Multi-Center Trial. Adria Laboratories. Evaluation of Compliance and Acceptance of Estraderm versus Oral Premarin as Post-Menopausal Estrogen Replacement Therapy. Clinical Medicine Research Institute. A Study of Patterns of Adminstering Cyclic/Continuous Estrogen. Ciba Pharmaceuticals. A Phase III Randomized Study of Cyclophosphamide and Cisplatin with or without Pretreatment with WR-2721 with Stage III or Stage IV Epithelial Ovarian Carcinoma. U.S. Bioscience. Multicentre, Randomized Survival Study of Monoclonal Antibody Radioimmuno-Therapy: A Multinational Study in Patients with Ovarian Cancer Carcinoma using HMFG1 Antibody labeled with 90 Y. Antisoma. A Phase II/III Trial of Chemotherapy. Alone Versus Chemotherapy Plus SCH58500 in Newly Diagnosed Stage III. Ovarian and Primary Peritoneal Cancer Patients with 0.5 cm and 2 cm Residual Disease Following Surgery. Schering Plough. Weekly Topotecan and Paclitaxel as Second or Thirdline Therapy for Advanced Epithelial Ovarian Cancer. Brookview Research, Inc. SCIENTIFIC EXHIBITS: Peri-operative Antibiotics in Pelvic Surgery: Efficacy, Safety and Clinical Indications. Xth World Congress of Gynecology and Obstetrics. San Francisco, California, October 1982; American College of Obstetricians and Gynecologists 31st Annual Clinical Meeting, Atlanta, Georgia May 1983. Benedict B. Benigno, M.D. Page 5 of 13 Revised: 1/29/2015
  6. 6. CLINICAL TRIALS: 1998 – 2004 Principal Investigator, Antisoma Smart Study Antisoma-Smart / Northside Hospital 432 Northside Hospital 561 Northside Hospital 602 Northside Hospital 609 2005 – Ongoing SE0502: A Phase II, Non-Randomized, Study of Abraxane plus Carboplatin in Patients with Recurrent Platinum-Sensitive Ovarian or Primary Peritoneal Cancer. 2004 - Ongoing CA009-0: A Phase II, Single Treatment Use of ABI-007 for the Treatment of Advanced Non-Hematologic Malignancies. 2005 - Ongoing HCT100414: An Open_label, Phase II, Multicenter Study of Intravenous Weekly Topotecan in Subjects with Recurrent or Persistent Endometrial Cancer. 1/2006 - Ongoing 104450: A Phase II, Open-Label Study Evaluating the Effect of GW786034 in Subjects with Ovarian Cancer. IND# 65,757. Benedict B. Benigno, M.D. Page 6 of 13 Revised: 1/29/2015
  7. 7. POST GRADUATE CONFERENCE ORGANIZER: Symposium on Pelvic Infection Lake Lanier Islands, Georgia February 1976 Gynecologic Oncology Atlanta, Georgia October 1979 Felix Rutledge Society Annual Meeting Atlanta, Georgia May 1984 Pitfalls in Coloposcopy Atlanta, Georgia 1988: January, March, July, September 1989: February, May, August, November 1990: April, August, November 1991: January, March, May, September, November New Trends in Colposcopy Atlanta, Georgia April 1988 Advances in Pelvic Surgery Atlanta, Georgia December 6-7, 1991 Colposcopy for the Primary Care Physician Atlanta, Georgia February 22, 1992 Technical Excellence in Pelvic Surgery Atlanta, Georgia December 4-5, 1992 Benedict B. Benigno, M.D. Page 7 of 13 Revised: 1/29/2015
  8. 8. COMMITTEE APPOINTMENTS: Northside Hospital NSH Bone Marrow Transplant Sub-Committee 1998 – Present NSH Executive Staff Committee 1992 – 1993, 1994 – 1995. NSH OB/GYN Committee 1982 – 1995 Chairman 1994 – 1995 NSH Foundations Advisory Board 1992 – 1996 Cancer Committee 1998 – 1996 Chairman 1998 – 1989 1991 – 1992 1992 – 1993 Interior Design Committee of Women’s Center Task Force 1993 Oncology Strategic Planning Task Force 1993 Top Tier Services Committee 1992 – 1993 Saint Joseph’s Hospital Regional Network Strategic Team Committee 1995 – 1996 Oncology Value Enhancement Committee 1995 – 1996 West Paces Ferry Hospital Cancer Committee; Institutional Review Board Cancer Committee of Georgia State Obstetrical and Gynecological Society UNIVERSITY COMMITTEE APPOINTMENTS: Curriculum Committee 1978 – 1982 Chairman of Education Committee 1984 – 1985 Clerkship in Gynecology and Obstetrics for Junior Medical Students Course Director 1979 – 1982 Human Investigations Committee 1979 – 1982 Cancer Committee 1979 – 1982 Benedict B. Benigno, M.D. Page 8 of 13 Revised: 1/29/2015
  9. 9. VIDEOTAPE PRESENTATIONS: 1. Gynecologic Infection (Salpingitis) Circulating Videotape Library, Emory University School of Medicine, 1976 2. Ovarian Carcinoma. Circulating Videtape Library, Emory University School of Medicine, 1978 3. Pelvic Inflammatory Disease. Circulating Videotape Library, Emory University School of Medicine, 1978 4. Pelvic Examination. Circulating Videotape Library, Emory University School of Medicine, 1981 PUBLICATIONS: 1. Thompson, J.D. and Benigno, B.B.: Vaginal Repair of Ureteral Injuries. American Journal of Obstetrics and Gynecology 111:601, 1971 2. Naib, Z. and Benigno, B.B.: A Non-Fertilized Human Ovum in a Hydrosalpinx Fluid Aspirate. Acta Cytologica. 22:93, 1977 3. Sawanobori, S., Ashman, R.B., Nahmias, A.J., Benigno, B.B., and LaVia, M.F.: Rosette Formation and Inhibition In Cervical Dysplasia and Carcinoma In Situ. Cancer Research. 37 (No. 12): 4332, 1977 4. Funt, M.I., Benigno, B.B., and Thompson, J.D.: The Residual Adnexa-Asset or Liability? American Journal of Obstetrics and Gynecology, 129 (No. 3): 251, 1977 5. Thompson, J.D. and Benigno, B.B.: Management of Patients With Recurrent Carcinoma of the Cervix. Dial Access A208 audiotape, April 1980 6. Hager, D., Wong, K., Lopez, B., Ramsey, C., Allen, S. Stargel, M., Thompson, S., Benigno, B.B., and Thompson, J.D.: The Microbiology and Therapy of Acute Pelvic Inflammatory Disease in Hospitalized Patients. American Journal of Obstetrics and Gynecology. 136 (No. 2): 179, 1980 7. Benigno, B.B.: General Prinicples of Radiation Therapy in the Treatment of Carcinoma of the Cervix Uteri. Bulletin of the Department of Gynecology and Obstetrics. Vol. II, No. 1, Winter, 1980 (Guest Editor) 8. Benigno, B.B.: Medical and Surgical Management of the Pelvic Abscess. Clinical Obstetrics and Gynecology. 24 (No. 4):1187, 1981 Benedict B. Benigno, M.D. Page 9 of 13 Revised: 1/29/2015
  10. 10. PUBLICATIONS (CONT.): 9. McLaren, J.R., Olkowski, S.L., Skeen, M.J., and Benigno, B.B.: Immunological and Clinical Responses of Patients with Squamous Cell Carcinoma of the Cervix To Adjuvent Immunotherapy Following Radiotherapy. Ravista Latinoamericana De Oncologia Clinca. 13, 4:15, 1981 10. Benigno, B.B.: Invasive Carcinoma of the Vulva. Bulletin of the Department of Gynecology and Obstetrics. Vol. IV, No. 1, Winter, 1982 11. Suarez, R.A., Grimes, D.A., Majmudar, B., and Benigno, B.B. : Diagnostic Endometrial Aspiration with the Karman Cannula. Journal of Reproductive Medicine. 28 (No. 1), January, 1983 12. Trevathon, E., Layde, P., Webster, L.A., Adams, J.B., Benigno, B.B., and Ory, H.: Cigarette Smoking and Dysplasia and Carcinoma In Situ of the Uterine Cervix. Journal of the American Medical Association. 250 (No. 4), July 22/29, 1983 13. Bures-Forsthoefel, J., Benigno, B.B., and Suarez, R.A.: Shortened Hospital Stay as a Benefit of Immediate Postoperative Nutrition Through a Special Duodenal Feeding Tube. Contemporary Ob/Gyn. 1986; 27:51 14. Benigno, B.B., and Thrasher, A.: Prophylactic Agents in Vaginal Hysterectomy: Evaluation of Piperacillin and Cephalothin. Infections in Surgery. Special supplement: Prophylaxis in General Surgery and Ob/Gyn., 1984 15. Benigno, B.B., and Thrasher, A.: Prophylactic Agents in Cesarean Section: Methods and Results in a Study of Piperacillin Versus Cefoxitin. Infections in Surgery. Special Supplement: Prophylaxis in General Surgery and Ob/Gyn., 1984 16. Benigno, B.B., Evrard, J., Faro, S., Ford, L.C., LaCroix, G., Lawrence, W.D., Ling, F.W., McNeeley, S.G., Nichols, D.H., and Sweet, R.L.: Prevention of Postoperative Infections in Patients Undergoing Vaginal Hysterectomy: A Randomized, Double-Blind, Controlled Comparison of Piperacillin, Cephalothin, and Cefoxitin. Surgery, Gynecology and Obstetrics. 163:421, 1986 17. Benigno, B.B., Ford, L.C., Lawrence, W.D., Ledger, W.J., Ling, F.W., and McNeeley, S.G.: Prevention of Postoperative Infection in Patients Undergoing Cesarean Section: A Double-Blind, Controlled Comparison of Piperacillin and Cefoxitin. Surgery, Gynecology and Obstetrics. 162 (No. 1):1, 1986 Benedict B. Benigno, M.D. Page 10 of 13 Revised: 1/29/2015
  11. 11. PUBLICATIONS (CONT.): 18. Berkeley, A.S., Freedman, K.S., Ledger, W.J., Orr, J.W., Benigno, B.B., Gordon, S.F., McGregor, J.A., Galask, R.P., Sevin, B.U.: Comparison of Cefotetan and Cefoxitin Prophylaxis for Abdominal and Vaginal Hysterectomy. American Journal of Obstetrics and Gynecology. 158 (No. 3, Part 2), March, 1988: 706 19. Nezhat, F., Nezhat, C., Benigno, B.B.: Four Ovarian Cancers Diagnosed During the Laparoscopic Management of 1,011 Women with Adenexal Masses. American Journal of Obstetrics and Gynecology. 167 (No. 3), September 1992: 790-796 20. Nezhat, C., Burrell, M.O., Nezhat, F.R., Benigno, B.B., Welander, C.E.: Combined Laparascopic/Vaginal Radical Hysterectomy with Para-Aortic and Pelvic Node Dissection. American Journal of Obstetrics and Gynecology. 166: 864-865. 21. Nezhat, C., Nezhat, F., Teng, N., Edraki, B., Nezhat, C., Burrell, M.O., Benigno, B.B., Ramirez, C.: The Role of Laparoscopy in the Management of Gynecologic Malignancy. Seminars in Surgical Oncology. 10:431-439 (1994) 22. Menedez, L., Benigno, B.B., and McDonald, J.: LI and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas. Molecular Cancer. 2004, 3:12 23. Verheijen RH, Massuger LF, Benigno BB, Epenetos AA, Lopes A Phase III Trial of intraperitoneal therapy with yttrium-90-labeled HMFG1 murine monoclonal antibody in patients with epithelial ovarian cancer after a surgically defined complete remission. Journal of Clinical Oncology 2006 Feb 1:24(4):571-8. 24. Warrenfeltz, S., Pavlik, S., Datta, S., Kraemer, E., Benigno, B.B., and McDonald, J.: Gene expression profiling of epithelial ovarian tumours correlated with malignant potential. Molecular Cancer. 2004, 3:27 25. N.J. Bowen, S. Logani, E. Dickerson, L. Kapa, M. Akhtar, B.B. Benigno and J.F. McDonald. 2006. Emerging roles for PAX 8 in ovarian cancer and endosalpingeal development. J. Gyn Can (in press). TEXTBOOK CHAPTERS: 1. Benigno, B.B.: Pelvic Inflammatory Disease. Gynecology and Obstetrics, Vol. 1. Edited by J. Sciarra. Harper & Row, 1981 2. Benigno, B.B.: Management of Advanced Cancer of the Ovary. Progress in Obstetrics and Gynecology. Churchill Livingstone, 1981 Benedict B. Benigno, M.D. Page 11 of 13 Revised: 1/29/2015
  12. 12. 3. McLaren, J.R., Olkowski, Z.L., Skeen, M.J., McConnell, F.M.F. , Benigno, B.B., Mansour, K., Nixon, D.W., Eells, R., and Shah, N.K.: Responses of Immune Parameters to Irradiation of Patients with Head and Neck Bronchogenic and Uterine Cervical Cancer and to Subsequent Immunotherapy. Immunopharmacolgic Effect of Radiation Therapy. Edited by J.B. Dubois, B. Serrou, and C. Rosenfield. Raven Press, New York, 1981 TEXTBOOK CHAPTERS (CONT.): 4. Benigno, B.B.: Gynecology, Medical Management of the Surgical Patient. Edited by M.F. Lubin, H.K. Walker, and R.B. Smith. Butterworth Publishers, Boston, 1982 RESEARCH PROJECTS: 1. Recurrent Carcinoma of the Cervix. Benedict B. Benigno, M.D., and Ernest Franklin, M.D., 1970 2. Review of Patients with Carcinoma In Situ Managed Conservatively. Benedict B. Benigno, M.D., and John Hoffman, M.D., 1975 3. Late Recurrence in Carcinoma of the Cervix and Emory University Affiliate Hospitals. Benedict B. Benigno, M.D., and Michael Robinowitz, M.D., 1975 4. Diagnostic Culdocentesis During D&C and Conization. Benedict B. Benigno, M.D., and Barbara Bolling, M.D., 1976 5. The Residual Adnexa - Asset or Liability? Benedict B. Benigno, M.D., and Mark Funt, M.D., 1976 6. An Evaluation of the Maturation Index in Post-Menopausal Patients. Benedict B. Benigno, M.D, and Winfield Murray, M.D., 1976 7. Intestinal Obstruction Following Previous Gynecological Surgery. Benedict B. Benigno, M.D., and Otis J. Williams, M.D., 1976 8. Ovarian Malignancy in Women Age Twenty-Five and Younger. Benedict B. Benigno, M.D., and Christopher Bieling, M.D., 1977 9. Final Report-Diagnostic Culdocentesis During D&C and Conization. Benedict B. Benigno, M.D., and Barbara Boling, M.D., 1977 10. Granulomatous Disease of the Pelvis. Benedict B. Benigno, M.D., and Mack Jones, M.D., 1977 Benedict B. Benigno, M.D. Page 12 of 13 Revised: 1/29/2015
  13. 13. 11. Hemotoperitoneums of Ovarian Origin in Women on Anticoagulants. Benedict B. Benigno, M.D., and Peter Kapernick, M.D., 1977 12. Pelvic Inflammatory Disease versus Appendicitis: A Diagnostic Dilemma. Benedict B. Benigno, M.D, and Terry Pope, M.D., 1977 13. The Use of Kleinhauer-Betke Test in Detection of Ectopic Pregnancy. Benedict B. Benigno, M.D., and Bill McKenzie, M.D., 1977 RESEARCH PROJECTS (CONT.): 14. Follow-up Cervical Conization after Cryosurgery for Cervical Intra-Epithelial Neoplasia. Benedict B. Benigno, M.D., and Alan LeRoy, M.D., 1978 15. Gonococcal Perihepatitis in Acute Salpingitis. Benedict B. Benigno, M.D., and David Bryan, M.D., 1979 16. Gestational Throphoblastic Disease. Benedict B. Benigno, M.D. , and Mark Gold, M.D., 1979 17. The Inpatient Management of Pelvic Inflammatory Disease. Benedict B. Benigno, M.D., and Harry Goldenberg, M.D., 1979 18. The Residual Adnexa Following Surgery for Pelvic Inflammatory Disease. Benedict B. Benigno, M.D., and Louis Kirtley, M.D., 1979 19. The Diagnostic Accuracy of Endocervical Curettage and Cervical Biopsy with Unsatisfactory Colposcopy. Benedict B. Benigno, M.D., and Mark Berry, M.D., 1979 20. Immunological and Clinical Responses of Patients with Squamous Cell Carcinoma of the Cervix to Adjuvent Immunotherapy Following Radiotherapy. Benedict B. Benigno, M.D., and Zbigniew Olkowski, M.D., 1980 21. Immediate Postoperative Nutrition with High Nitrogen Vivonex Through a Special Duodenal Feeding Tube. Benedict B. Benigno, M.D., and Jana Bures- Forsthoefel, M.D., 1981 22. Endometrial Carcinoma: Emory University Affiliated Hospitals’ Experience 1969-1978. Benedict B. Benigno, M.D., and Veronica Daly, M.D., 1981 23. The Management of Acute Pelvic Infections by Single-Agent Therapy with Cefoxitin. Benedict B. Benigno, M.D., and Ian Gluck, M.D., 1981 Benedict B. Benigno, M.D. Page 13 of 13 Revised: 1/29/2015

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