Attachment A
1
Cancer Interest/ Focus:
Planned Cancer Research Interactions/Collaborations:
Applicant Name:
Attachment B
UNIVERSITY OF MARYLAND PROGRAM IN ONCOLOGY
REQUEST FOR APPOINTMENT IN THE UNIVERSITY OF MARYLAND SCHOOL OF
ME...
Attachment C
Applicant Name: __________________________________________________
Program in Oncology Research Programs
Plea...
Molecular and Structural Biology Program
Contact: Alan Tomkinson, Ph.D. Professor of Radiation Oncology
Program Descriptio...
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Cancer Center Membership Application Form

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Cancer Center Membership Application Form

  1. 1. Attachment A 1 Cancer Interest/ Focus: Planned Cancer Research Interactions/Collaborations: Applicant Name:
  2. 2. Attachment B UNIVERSITY OF MARYLAND PROGRAM IN ONCOLOGY REQUEST FOR APPOINTMENT IN THE UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE PROGRAM IN ONCOLOGY I hereby request membership/associate membership in the University of Maryland School of Medicine Program in Oncology. I understand and accept the following obligations that such an appointment confers: 1. Support the basic concept, mission, and goals of the Cancer Center. 2. Participate fully in respective research program, collaborative efforts, and communications about research and patient care initiatives. 3. Provide the Cancer Center with the information necessary to maintain current information about scientific activity and grant support in order to maintain the Center’s database on oncology-related activities. 4. Request funds in grant applications to support the shared resource services provided to them by Cancer Center. 5. Attend cancer seminars and program meetings in areas of interest. 6. Report all funded activities to the Cancer Center at the time membership is granted, and as requested by the Director 7. Include recognition of membership in the Program in Oncology and the Cancer Center on all cancer-related academic papers, grants, journal articles, poster sessions, and/or abstracts. 8. Participate in cancer-related educational activities (both medical and graduate school) sponsored by the Cancer Center. 9. Participate in the Cancer Center core grant program project and training application process as requested. 10. Participate in seminars and conferences. Applicant Name (please print): ______________________________________________ Applicant Signature: ______________________________________________________ Concurrence: ____________________________________________________________ Department Chair 2
  3. 3. Attachment C Applicant Name: __________________________________________________ Program in Oncology Research Programs Please indicate your primary (1) and secondary (2) interest by program. Experimental Therapeutics Program Contact: Douglas D. Ross, M.D., Ph.D., Professor, Department of Medicine Program Description: The unifying theme of the Program is to build translational clinical trials based on innovative and novel laboratory research projects. The Program goals are to: identify cancer-specific targets that can be exploited for cancer prevention or therapy, and translate these findings to clinical trials; rationally design agents to combat cancer directed at specific targets identified; and conduct clinical trials that test the efficacy of novel targeted anticancer therapeutic agents or improve the efficacy of existing agents, and translate clinical findings to laboratory investigations. Major research areas of interest include: cancer drug resistance; cell proliferations, signaling, growth factors, and apoptosis; angiogenesis; Computer- Assisted Drug Design (CADD), screening and lead optimization; and clinical trials that specifically test the efficacy of novel agents aimed at identified targets. Tumor Immunology and Immunotherapy Program Contact: Scott E. Strome, M.D., Chair, Department of Otorhinolaryngology--Head and Neck Surgery Program Description: The principal scientific goals of the Program are to develop, characterize, and apply immunological approaches for the prevention, diagnosis, treatment and monitoring of premalignant and malignant diseases and disease progression. The specific aims include the development and characterization of molecular and immunologic strategies for manipulating the innate and adaptive immune responses to malignancy; the design and conduct of preventive and therapeutic trials for selected cancers utilizing these molecular/immunological strategies; and the development of an immunological monitoring program to be used in conjunction with clinical outcomes to evaluate the efficacy of immunotherapy and conventional therapies. Hormone Responsive Cancers Program Contact: Amy M. Fulton, Ph.D., Professor of Pathology Program Description: The overall goals of the Program are to understand the pathophysiological processes that determine the behavior of malignancies of hormonally-responsive tissues, chiefly prostate and breast. These studies address mechanisms by which hormone-refractory disease develops and identify novel targets. The specific aims of the Program are to: identify mechanisms of de novo and acquired hormone-resistance; identify novel diagnostic, prognostic and therapeutic targets; elucidate the biology of tumor angiogenesis and develop therapeutic strategies; define the mechanisms mediating tumor invasion and metastasis and develop therapeutic strategies; and identify causes and reduce cancer disparities. 3
  4. 4. Molecular and Structural Biology Program Contact: Alan Tomkinson, Ph.D. Professor of Radiation Oncology Program Description: The overall goals of the Program are to understand the cellular processes that normally regulate cellular proliferation and maintain genome stability and how these processes may contribute to cancer formation. The research interests of the Program members can be divided into three broad areas: DNA damage, repair and genome instability; RNA biology: and signal transduction. The specific aims include: gaining molecular insights into cellular processes that regulate cellular proliferation and maintain genome stability; evaluating proteins as novel therapeutic targets; and identifying small molecules that will serve as lead compounds for the development of novel therapeutic agents. Viral Oncology Program Contact: Marvin S. Reitz, Jr., Ph.D. Professor, IHV and Department of Microbiology and Immunology Program Description: The overall goal of the Program is to understand how viral infections contribute to the development and progression of cancers. This includes not only the mechanisms by which some viruses, such as papillomavirus and some herpesviruses, contribute directly to tumorigenesis, but also more indirect mechanisms, such as dysregulation of different aspects of immunity by human immunodeficiency virus (HIV). These include the impairment of the control of tumorigenic viruses, the creation of microenvironments that can facilitate the formation and/or maintenance of cancer, such as inflammation and angiogenesis, and the abrogration of innate immunity against tumors. 4

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