Peterson immortal life training

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Presentation on HeLa cells and the Life of the Mind session by Dr. Peterson.

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Peterson immortal life training

  1. 1. Life of the Mind 2011<br />Facilitator Training Presenter: Cynthia Peterson<br />
  2. 2. Questions to consider…<br />What is the science of Cell Biology?<br />What was the breakthrough with HeLa cells?<br />What milestones in cell biology studies were possible because of HeLa cells?<br />How does one scientist react to this book?<br />What about research at the University of Tennessee?<br />
  3. 3. Questions to consider…<br />What is the science of Cell Biology?<br />What was the breakthrough with HeLa cells?<br />What milestones in cell biology studies were possible because of HeLa cells?<br />How does one scientist react to this book?<br />What about research at the University of Tennessee?<br />
  4. 4. What is the science of Cell Biology?<br />Work with cells in laboratory setting<br />Learn about cell structure, division, organization, normal and disease processes<br />Microscopy gives an up-close picture of the cells<br />Important step in drug development<br />
  5. 5. What is the science of Cell Biology?<br />Work with cells in laboratory setting<br />Learn about cell structure, division, organization, normal and disease processes<br />Microscopy gives an up-close picture of the cells<br />Important step in drug development<br />
  6. 6. What is the science of Cell Biology?<br />
  7. 7. Questions to consider…<br />What is the science of Cell Biology?<br />What was the breakthrough with HeLa cells?<br />What milestones in cell biology studies were possible because of HeLa cells?<br />How does one scientist react to this book?<br />What about research at the University of Tennessee?<br />
  8. 8. What was the breakthrough with HeLa Cells?<br />Human cells cultured for the first time! (Gey had cultured other species and had worked for over 20 years with this aim)<br />Cancer researchers considered cultured human cells to hold the key to discovering a cure<br />HeLa cells are a “workhorse” for cell biology: easy to grow, ideal for microscopy, transfection <br />Provided a model cell line for studying normal cellular processes as well as many diseases<br />
  9. 9. Original Research on Polio Infection<br />Infected Cells<br />Uninfected Cells<br />
  10. 10. Questions to consider…<br />What is the science of Cell Biology?<br />What was the breakthrough with HeLa cells?<br />What milestones in cell biology studies were possible because of HeLa cells?<br />How does one scientist react to this book?<br />What about research at the University of Tennessee?<br />
  11. 11. What milestones in cell biology were possible because of HeLa cells?<br />Polio infection process and vaccine development <br />Advances in microscopy<br />Research to isolate single cells and eventually to establish clonal cell lines<br />Methods established for chromosome spreading and karyotyping<br />Ongoing research on telomerase (Nobel Prize 2009)<br />New siRNA technologies for gene knockdowns<br />
  12. 12. What milestones in cell biology were possible because of HeLa cells?<br />
  13. 13. Questions to consider…<br />What is the science of Cell Biology?<br />What was the breakthrough with HeLa cells?<br />What milestones in cell biology studies were possible because of HeLa cells?<br />How does one scientist react to this book?<br />What about research at the University of Tennessee?<br />
  14. 14. How does one scientist react to this book?<br />Medicine and Science<br />History of modern medicine<br />Doctor/Patient Relationship<br />Ethics, Values, and Civility<br />Research Ethics<br />Legal Issues<br />
  15. 15. How does one scientist react to this book?<br />Research<br />Journalism<br />Finding a passion<br />Social, Economic and Political Aspects<br />Socioeconomic status<br />Race, class and gender<br />
  16. 16. Questions to consider…<br />What is the science of Cell Biology?<br />What was the breakthrough with HeLa cells?<br />What milestones in cell biology studies were possible because of HeLa cells?<br />How does one scientist react to this book?<br />What about research at the University of Tennessee?<br />
  17. 17. What about research at the University of Tennessee?<br />HeLa cells are used by many researchers across campus…..<br />Where is a protein in the cell?<br />What are its binding partners?<br />How does localization change with cell cycle?<br />Use transfection methods to introduce new genes into the cell<br />Use knockdown technologies to selectively reduce levels of specific proteins<br />Examples from my own department<br />Mobility of proteins in membrane<br />Localize proteins within nuclear envelope<br />Finding specific DNA/protein interactions<br />An example from an undergraduate researcher<br />
  18. 18. Questions???<br />

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