Healthy Heart – An Ayurvedic ApproachUnder the Guidance of, By,Dr.Ashalatha.M. Dr.Tanmaya.K.AcharyaH.O.D., Dept of P.G.Studies inDravyaguna, II M.D., Dept of DravyagunaG.A.M.C., Bengaluru G.A.M.C., Bengaluru
Introduction• India has the largest Cardio-vascular Disease rate in the world.• Ganas mentioned specifically in Charaka and Sushrutha Samhita for Hrdya karma and Hrd roga• Hrdya gana, Parushakadi gana, Bruhatyadi gana, Utpaladi gana, Balya dashemani, Lekhaneeya dashemani.
Arka :Calatropis proceraPhytoconstituents ActivityCalotropagenin Inhibitors of Na(+) /K(+) - ATPase to regulate heart contractions
Conclusion• Various approach towards cardio-protective activity: • Protective: Amra, Madhuka, Draksha • Anti-hypertensives: Bruhati, Brahmi • Inotropic activity : Karamarda • Chronotropic activity : Kamala, Arka • Anti-cholesterol : Chitraka• The need to fill the lacuna between Literature Research Implementation• Rediscover the connection between ‘Plant’ and ‘Health’
References• Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infarcted rats. Department of Biochemistry, University of Madras, A.C. Tech., Guindy campus, Chennai-600 025, India.• BIOSYNTHESIS OF CAR1SSOL AND CARISSIC ACID. Department of Chemistry, University of Karachi, Karachi-75270, Pakistan.• Solanum indicum ssp. distichum extract is effective against L-NAME-induced hypertension in rats. Department of Pharmacology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.• Madhucosides A and B, protobassic acid glycosides from Madhuca indica with inhibitory activity on free radical release from phagocytes. Department of Natural Products, National Institute of Pharmaceutical Education and Research, Sector 67, SAS Nagar, Punjab 160062, India.• Diet enriched with procyanidins enhances antioxidant activity and reduces myocardial post- ischaemic damage in rats. Istituto Chimico Farmaceutico Tossicologico, University of Milan, Italy.• Effects of neferine on transmembrane potentials of guinea pig myocardium. Li GR, Li XG, Lü FH• Bacopa monnieri and its constituents is hypotensive in anaesthetized rats and vasodilator in various artery types. Department of Physiology, Faculty of Medical Science, Naresuan University, Phitsanulok 65000, Thailand.• Hypolipidaemic and antiatherosclerotic effects of plumbagin in rabbits. Department of Zoology, University of Rajasthan, Jaipur.• Rapid identification of calotropagenin glycosides using high-performance liquid chromatography electrospray ionisation tandem mass spectrometry. Sophisticated Analytical Instrument Facility, Central Drug Research Institute, Lucknow, 226001,
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