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Thailand Bioresource Research Center (TBRC): Network Integration of Quality Management for Culture Collection
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Thailand Bioresource Research Center (TBRC): Network Integration of Quality Management for Culture Collection

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This slide was presented by Dr Lily Eurwilaichitr at the ICCC13, Beijing, China on Sept 24, 2013

This slide was presented by Dr Lily Eurwilaichitr at the ICCC13, Beijing, China on Sept 24, 2013

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Thailand Bioresource Research Center (TBRC): Network Integration of Quality Management for Culture Collection Presentation Transcript

  • 1. Thailand Bioresource Research Center (TBRC): Network Integration of Quality Management for Culture Collection Copyright @2013 TBRC, BIOTEC, Thailand TBRC: a National BRCTBRC: a National BRC Bioresources Technology Research Unit, National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand http://www.biotec.or.th/btu Thailand Bioresource Research Center (TBRC), Thailand http://www.tbrcnetwork.org Lily Eurwilaichitr and Supawadee Ingsriswang
  • 2. Microbes: a key to success in bio-based economy Chemicals Materials Energy/Fuels Renewable resources (e.g. palm, sugar cane) Fossil resources (e.g. petroleum) Research Utilization Preservation Distribution TBRC Enzyme Microbe Thermocatalysis Bio-process Industrial biotechnology Biorefinery BioFuels Chemicals Bioplastics Drugs Food/Feed Biomass Agriculture Microbial Diversity/ Community Competitive advantage Copyright @2013 TBRC, BIOTEC, Thailand
  • 3. TBRC: a National BRCTBRC: a National BRC Bioresource Research Center Bioresource Research Center Copyright @2013 TBRC, BIOTEC, Thailand
  • 4. Thailand Bioresource Research Center TBRC Food and Feed Innovation Center NSTDA-JGSEE Integrative Biorefinery Laboratory New initiatives of BIOTEC 4 Copyright @2013 TBRC, BIOTEC, Thailand
  • 5. Bioresources Data Network TBRC and its networkTBRC and its network TBRC Copyright @2013 TBRC, BIOTEC, Thailand
  • 6. Bioresources Data Network TBRC: Networking the UniversitiesTBRC: Networking the Universities TBRC Copyright @2013 TBRC, BIOTEC, Thailand Universities
  • 7. TBRC Network Structure Copyright @2013 TBRC, BIOTEC, Thailand Regional TBRC Hubs TBRC Members (Collections ) TBRC
  • 8. Copyright @2013 TBRC, BIOTEC, Thailand TBRC Member
  • 9. Copyright @2013 TBRC, BIOTEC, Thailand Users of TBRC must be guaranteed reliable, high- quality biological resources and information.
  • 10. =Authenticity of biological materials, databases and bioinformatics and accuracy of labelling. =Processing of cultures, cell lines, and genetic constructs, including procedures and standards for ensuring their long-term stability and quality control. =Accuracy of the data collected and supplied. =Expertise and training of human resources, particularly of a new generation of taxonomists able to use molecular techniques and informatics. =Sharing of expertise among centres through co-ordination and networking. Copyright @2013 TBRC, BIOTEC, Thailand
  • 11. Q1Q1 Q2Q2 Q3Q3 Quality of Microbial Cultures Quality of Data Quality of Services Quality Management System @TBRCCopyright @2013 TBRC, BIOTEC, Thailand
  • 12. Quality Management System @TBRC Copyright @2013 TBRC, BIOTEC, Thailand TBRC operation Cultures QMS Data QMS Services QMS Standard and Procedures Deposit Preserve (subculture) Depositor, Officer, Document, Correctness, Consistency, Missing info Contamination, Preserve (storage) Distribute
  • 13. • Science in the 21st Century is Data-Driven Science. • Data Integration is key to Biological DB Management System. • Data Quality is a top concern of data integration. High quality data will lead to knowledge for research excellence. • High quality data –well organized, documented, preserved and accessible –accuracy and validity Copyright @2013 TBRC, BIOTEC, Thailand
  • 14. Copyright @2013 TBRC, BIOTEC, Thailand
  • 15. Copyright @2013 TBRC, BIOTEC, Thailand TBRC Web services iCollect: Software for TBRC Material ProvidersiCollect: Software for TBRC Material Providers
  • 16. Facilitate the workflow of BRC • Sample/Specimen Management • Storage Management • Quality Control • Service Management iCollect:iCollect: An Enhanced Solution for Biological Resources ManagementAn Enhanced Solution for Biological Resources Management Web services (SOAP) TBRC TBRC Enable cross-platform data sharing Data Standardization and Integration Control the quality of data Data Verification & Validation, Data Traceability Copyright @2013 TBRC, BIOTEC, Thailand
  • 17. Built-in workflow system for quality control – Tracking the status for each step in service process Copyright @2013 TBRC, BIOTEC, Thailand
  • 18. Copyright @2013 TBRC, BIOTEC, Thailand Database Management for BRC Collection Reader Collection Reader Data Structure Data Structure DataData Taxonomy Validator Taxonomy Validator Geolocator Validator Geolocator Validator
  • 19. • Taxon Data Crosschecking with Species2000 and other DBs • Check spelling (province, etc) • Checking via Google Map Sample Management Copyright @2013 TBRC, BIOTEC, Thailand Database Management for BRC Data Validation –Consistency, Integrity
  • 20. Copyright @2013 TBRC, BIOTEC, Thailand Microbe++: Using text mining to build TBRC strain catalog
  • 21. Integration to BIOTEC & Country’s Biotech industry TBRC • Strategic microbe catalogues • Enzyme producer databases Prototype products + Formulation + Production Design & Engineering Microbes Enzymes Microbial agents Chemicals One-stop focal point for microbial product development & demonstration L I3 years 3 months Copyright @2013 TBRC, BIOTEC, Thailand
  • 22. Copyright @2013 TBRC, BIOTEC, Thailand Maintaining the quality of data and materials and their validation will require harmonised co- ordination between BRCs and bioinformatics databases so as to provide the range of services required by the international community of life scientists and the global biotechnology industry.