Access and Benefit Sharing (ABS) in Bio Prospecting

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Satoshi Nimura, President - Nimura Genetic Solutions Co., Ltd. - Japan …

Satoshi Nimura, President - Nimura Genetic Solutions Co., Ltd. - Japan

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  • confidential
  • Confidential Jun 1, 2010

Transcript

  • 1. Access and Benefit Sharing (ABS) in BioProspecting 27 May, 2010
  • 2.
  • 3.
  • 4. CBD   Convention on Biological Diversity
    • 193 countries in CBD (2010)
    • Conservation
    • Sustainable Use
    • Benefit Sharing (incl. capacity building)
    • Resource country’s right
  • 5. Bioprospecting
    • Bioprospecting is an effort to find academic or commercial values from biological diversity
  • 6. Biopiracy
    • Bio prospecting activities without Prior Informed Consent (PIC)
      • From authority or community, if necessary
      • Should include benefit sharing scheme
    •   
  • 7. Are you from local institute? Are you from public sector ? You have proper permission? Are you from public sector ? You have proper permission? You have proper permission? You have proper permission? Yes Yes Authorised bioprospector Bio Pirates No, we are foreigner No we are from private   Yes NO ! YES ! No we are from private
  • 8. Keys for good ABS practice
    • Nimura Principles
    • Keep Biological Resources in Resource Countries
    • Practical Technology Transfer
    • Sharing Intellectual Properties (IP)
    • with Resource Countries
  • 9. Value of Resources: Expectation Gap between owners and users Medicinal Value of Biological Resources Expectation of Resource Countries Reality in User Countries soil samples isolated microbes extracts leads patent medicines pre-clinical clinical purified hit compound hit extracts
  • 10. Access to resources should be this? Ideal to user country Ideal to resource country Low high
    • From collection to
    • Drug development
    • in resource country
    2. User establish its laboratory in resource country 3. Research as much as possible in resource country 4. Free supply of Biological material Possibility to be accepted by user country
  • 11. Governmental partners in Malaysia   Universiti Malaysia Sabah
  • 12. Governmental partners in Bhutan Royal government of Bhutan Ministry of Agriculture and forestry National Biodiversity Centre
  • 13. Resource country NGS client ABS scheme
    •   IPR (co-own among 3 parties)
    •   Client has no direct negotiation
    •   Technology transfer is carried out through NGS
    •   Biological Resources will not go out of Resource country, unless any process is impossible to carry out in Resource country.
    Agreement Royalty + Mileston To NGS Agreement
  • 14. Research Result example 1 Malaysian application 2006/05   PCT application 2007/05 Japan, US, EU Novel anti-biotics (Bispolides) Microbispora sp
  • 15. Research Result example 2 New invention on non-pharmaceuticals Application of New Firefly Luciferase to Patent Registration office in Malaysia on 25 th of Feburary, 2010 Applicant: Olympus Corporation Nimura Genetic Solutions Co., Ltd. Perak State Development Corporation
  • 16. NGS model Resource Country X,Y,Z… Bhutan Malaysia NGS(J) SBC FRIM UMS NGS(M) Clients NGS Group Clients
  • 17. Approved and similar Under negotiation Future target Future expanding plan
  • 18. Conclusion
    • Bioprospecting is one of most important method of Sustainable Use of Biodiversity
    • Proper ABS scheme is required
    • Resource Countries’ demands should be entertained
    • Resource Countries’ support is also important
  • 19. Thank you for your attention
  • 20. Bioprospecting activity: Misconstrued for Biopiracy Chairman   NIMURA Satoshi < National Conference on Agrobiodiversity >
  • 21. Contents
    • 1. What is Bioprospecting?
      • pre CBD and post CBD
      • Operation example
    • 2 . What is Biopiracy?
      • Definition
    • 3. How do we do in CBD era?
      • Expectation gap between resource countries
      • and user countries
      • Operation examples
    • 4. Conclusion: For reasonable ABS.
  • 22. What is Bioprospecting ?
    • It was called “Plant Hunting”
  • 23. History of Bioprospecting ( Pre CBD )
    • Bioprospecting was a respected adventure as well as a part of expanding policy
    • European big countries competed for bioresources.
    • Their quest for spices.
    Captain Cook
  • 24. History of Bioprospecting ( Pre CBD )
    • Big names in plant-hunting
    •      
    Sir Joseph Banks Most famous British plant hunter in 18 C. As a Director General of Royal Kew Garden, organized plant hunters to overseas. with Navy assist. Rosa banksiae was named after his wife.
  • 25. History of Bioprospecting ( Pre CBD )
    • Big names in plant-hunting
    •      
    Philipp Franz von Siebold Charles   R.   Darwin Dutch biologist stayed in Japan. Introduced Many Japanese indigenous Plant to Europe. His theory come Through his experience As onboard biologist.
  • 26.
    • Big names in plant-hunting
    •   Alfred ・ R. Wallace and Wallace line
    •      
    History of Bioprospecting ( Pre CBD )
  • 27. History of Bioprospecting ( Pre CBD )
    • Famous incident
    •    Mutiny on the Bounty
      • The Bounty had a mission to deliver seedlings
      • Of Bread fruit from Tahiti to East Indies.
      • No.2 kicked out Captain from the Bounty.
  • 28. History of Bioprospecting ( Pre CBD )
    • FAO’s statement ( 1983 )
    •    「 International Undertaking on Plant Genetic
    • Resources 」
    •     
    • “ Biological Resources belong to
    • all mankind.”  “ common treasure”    
        •  
        • Still dominant idea for many scientists.
  • 29. History of Bioprospecting ( Pre CBD )
    • As a Strategic Resources
    •    Merck & Costa Rica
      • Access right to bio resources
      • in Costa Rica(1991)
      • First Exclusive Access
      • agreement of its kind
      • This agreement indicates biological access could be
      • Strategic resources to fight for, as petroleum.
    Costa Rica   INBio
  • 30.
    • Heat-up discussions
      • Southern counters against Northern globalization.
      • Resource countries consider it as great advantage for protecting their right.
    • Domestic regulations
      • Philippines' president order 247
      • India’s biodiversity law
      • etc.
    CBD arrived
  • 31. Definition of Bioprospecting
    • Bioprospecting is an effort to find academic or commercial values from biological diversity
    Common image of prospecting
  • 32. Bioprospecting (NGS’s case) Collection trip
  • 33. Bioprospecting (NGS’s case) Soil collection isolation collection Characterization Genetic analysis fermentation Extraction Assays HIT Structure elucidation
  • 34. NGS company profile
    • Company Neural Genetic Solutions Co., Ltd.
    • Established     26 June, 2000
    • Address   2 nd Floor, 1-19-10, Osaki, Shinagawa-ku,
    • Tokyo, 141-0032
    • Management Chairman Satoshi Nimura
        •   President Keiichi Kiyota
    • Capital    410,000,000 yen (about US$3.8 mil)
    • Staff    15 ( 7 PhD. 3 Master, as of Nov. 2006 )
    • Company Nimura Genetic Solutions (M) Sdn. Bhd
    • Established    Dec 2000  ( Oct 2002 Lab start operation )
    • Capital     RM 2,030,000 (about US$550,000)
    • Staff   28 ( 1 PhD. 7 Master, 10 Bachelor as of Nov. 2006 )
    • Address   Third floor, Chemistry Building,
    • Forest Research Institute Malaysia (FRIM)
    • Kepong 52109, Kuala Lumpur, Malaysia
  • 35. Biopiracy : definition
    • Bio prospecting activities without Prior Informed Consent (PIC)
      • From authority or community, if necessary
      • Should include benefit sharing scheme
    •   
  • 36. Difference between Bioprospecting and Biopiracy Bioprospecting Legal Bioprospecting Illegal Bioprospecting Foreigner’s Bioprospecting Domestic Bioprospecting academic academic Commercial Commercial Commercial Commercial
  • 37. How do we do in CBD era?
    • Foreign company has to cope with   these.
      • Discussion for agreement
      • Operation of collaboration
      • Avoid Speculations
      • Handling of
      • Intellectual property
  • 38. Value of Resources: Expectation Gap between owners and users Medicinal Value of Biological Resources Expectation of Resource Countries Reality in User Countries isolates identified strains active isolates leads patent medicines pre-clinical clinical hit extracts purified hits extracts
  • 39. Access to resources should be this? Ideal to user country Ideal to resource country Low high
    • From collection to
    • Drug development
    • in resource country
    2. User establish its laboratory in resource country 3. Research as much as possible in resource country 4. Free supply of Biological material Possibility to be accepted by user country
  • 40. Business Scheme 1
    • Extract supply scheme
    • Controllable
    • Not beneficial
  • 41. Business Scheme 2
    • Screening contract scheme
    • improvement
    • client satisfaction is a problem
  • 42. Business Scheme 3
    • Client visit scheme
    • more commitment from client
    • better improvement
  • 43. Real Biopiracy or not?
    • Speculation can kill the company.
    • Rootless rumor is an offence.
    • Big established companies have proper internal regulation for not committing Biopiracy.
    • Through our practical observation, academic fields commit more Biopiracy, unconsciously.
  • 44. Conclusion
    • Bioprospecting is not Biopiracy at all, If proper process is taken.
    • Biopiracy is not always carried out by foreigners and commercial people, by domestic and academic people as well.
    • Prevent rootless negative speculation or misuse of the word “Biopiracy” is essential for foreign investment into Malaysia.