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Notion Anaphylaxis shock
Types of hypersensitivity reaction's
Singe’s & Symptom’s
The term derived from greek language ana – (without) ,
phylaxis – (protection). A sudden, severe allergic reaction
characterized by a sharp drop in blood pressure, urticaria
(skin rash), and breathing difficulties that is caused by
exposure to a foreign substance, such as a drug or bee
venom, after a preliminary or sensitizing exposure. The
reaction may be fatal if emergency treatment is not achieved
immediately, treatment including epinephrine injections.
Also called anaphylactic shock.
By the Type of shock:
By type of development:
The diagnosis of anaphylaxis is based upon symptoms that occur
suddenly after being exposed to a potential trigger.
Usually in dental clinic it will be more hard to get conclusive diagnosis.
• severe asthma attack
• heart attack
• panic attack
• food poisoning
- Those differential diagnosis are very similar to anaphylaxis shock and
a doctor could get a wrong diagnosis due to lack of tools in reach to
- An increased amount of tryptase protein can be measured in a blood
sample collected during the first three hours after anaphylaxis
symptoms have begun.
- Tryptase levels are seldom elevated in food-induced anaphylaxis
Place patient in horizontal with legs up position.
Establish and maintain airway.
Give oxygen via nasal airway as needed.
Place a tourniquet above the reaction site.
Epinephrine at the site of antigen injection.
Start IV to rise BP.
• Adrenalina sol. – 0.1% 0.5 ml, if patient state doesn't improve in 10-15 min, we
Introduce 1.0 ml more of sol.
• Suprastine sol. – 2% 1ml.
• Prednisolone sol. 30-60 mg (unique dose) or hydrocortisone 75-125 mg.
• Caffeine sol. Or cordiamine, or corazoli – 20% 1-2 ml.
• In case of bronchospasm: eupheline sol. – 2.4% 5-10 ml or galidore sol. – 2ml (i/m).
• To maintain cardiac activity are given cardiac glycosides & diuretics: lazex sol. – 2-4 ml (i/v),
Corglicon sol. – 0.06% 0.5-1 ml (i/v).
• In case of cardiovascular insufficiency: strophantini sol. 0.05% 0.5-1 ml, mazatoni sol. 0.1% 1m
• Ionic sol. of NaCl 0.9% 400 ml or glucose sol. 5-10% 400 ml, in perfusion introduced dopamin
sol. 200 gr or noradrenaline 0.1% 1ml.
• Injection place should be infiltrated with adrenalin sol.
• Artificial respiration with extern massage of the heart.
Avoid the responsible allergen (e.g. food,
drug, latex, etc.).
Keep an adrenaline kit (e.g. Epipen) and
Benadryl on hand at all times.
Wear medic Alert bracelets .
Venom immunotherapy is highly effective
in protecting insect-allergic individuals.