Your SlideShare is downloading. ×
Upcoming SlideShare
Loading in...5

Thanks for flagging this SlideShare!

Oops! An error has occurred.


Saving this for later?

Get the SlideShare app to save on your phone or tablet. Read anywhere, anytime - even offline.

Text the download link to your phone

Standard text messaging rates apply



Published on



Published in: Education

  • Be the first to comment

No Downloads
Total Views
On Slideshare
From Embeds
Number of Embeds
Embeds 0
No embeds

Report content
Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

No notes for slide


  • 1. Photolithography
  • 2. Introduction
    The process through which we make microfluidic chips is called lithography. This presentation is an introduction to how we do lithography in the Zarelab.
    There are actually two types of lithography involved in making a microfluidic chip:
    • Photolithography: Making a mold on a silicon wafer using UV light to etch a design
    • 3. Soft lithography:Using the mold to make a chip from polydimethylsiloxane (PDMS) polymer
  • History
    • Historically, lithography is a type of printing technology that is based on the chemical repellence of oil and water.
    • 4. Photo-litho-graphy: latin: light-stone-writing
    • 5. In 1826, Joseph NicephoreNiepce, in Chalon, France, takes the first photograph using bitumen of Judea on a pewter plate, developed using oil of lavender and mineral spirits
    • 6. In 1935 Louis Minsk of Eastman Kodak developed the first negative photoresist
    • 7. In 1940 Otto Suess developed the first positive photoresist.
    • 8. In 1954, Louis Plambeck, Jr., of Du Pont, develops the Dycryl polymeric letterpress plate
  • Photolithography
    • The purpose of photolithography is to create small structures or features on a silicon wafer using photoresist. Features are made out of photoresist by etching with UV light.
    Photolithography uses this general process:
    • Wafer priming
    • 9. Spincoating
    • 10. Prebaking
    • 11. Exposure
    • 12. Development
    • 13. Postbaking (varies depending on resist type)
  • Photoresist
    • Photoresist is an organic polymer which changes its chemical structure when exposed to ultraviolet light.
    • 14. It contains a light-sensitive substance whose properties allow image transfer onto a printed circuit board.
    • 15. There are two types of photoresist: positive and negative
  • Positive and Negative
    • Exposure to UV light makes it more soluble in the developer
    • 16. Exposed resist is washed away by developer so that the unexposed substrate remains
    • 17. Results in an exact copy of the original design
    • 18. Exposure to UV light causes the resist to polymerize, and thus be more difficult to dissolve
    • 19. Developer removes the unexposed resist
    • 20. This is like a photographic negative of the pattern
  • Masks
    • Prior to doing photolithography, we need to make exposure masks for our mold. These are used during the exposure step of photolithography to etch the desired design into the photoresist.
    70 µm x 7 µm Channel
    70 µm x 1 µm Channel
    • The channel mold has two different feature thicknesses: 7 µm and 1 µm. Therefore, we need two separate masks for the two different resist layers.
  • Negative Resist Photolithography
    Step 1: Wafer Priming
    All wafers need to be primed with HMDS to increase adhesion of the photoresist to the wafer. This can be done either in the yes oven or svgcoat track.
    Step 2: Spincoating
    The wafer is placed on a rotating platform, or “chuck”, and held via vacuum suction. Resist is poured onto the wafer. The wafer spins at high speed (several thousand rpm’s). The speed determines the resist thickness.
  • 21. Negative Resist Photolithography
    Step 3: Prebaking
    Following spincoating, wafers need to be baked on a hotplate.
    Step 4: Exposure
    Wafers are exposed to UV light using the karlsuss or evalign instruments. A mask is used to transfer the design to etch the design onto the spincoated resist. The energy and time required can vary with resist thickness, so refer to the SU-8 data sheets.
  • 22. Negative Resist Photolithography
    Step 5: Postbaking
    Following exposure, wafers need to be baked on a hotplate again. Refer to the SU-8 data sheets for baking times.
    Step 6: Development
    Wafers are placed in SU-8 developer, which removes resist that was not exposed to UV light. Only the desired features remain. Development times vary with thickness, so refer to the SU-8 data sheets.
  • 23. Positive Resist Photolithography
    For all subsequent layers after the first layer, do NOT re-prime the wafer. Wafers with photoresist on them cannot be put in priming instruments.
    Step 1: Spincoating & Prebaking
    For positive resist (SPR 220), we use the svgcoat instruments. These are automated tracks where pre-set recipes are used for specific thicknesses. Different thicknesses require different prebaking strategies. Ask a section member for advice.
  • 24. Positive Resist Photolithography
    Step 2: Exposure
    Once again, the karlsuss or evalign instruments are used for exposure. There are no reliable data sheets for SPR resist. Therefore, ask a section member for advice on what settings to try first.
    Step 3: Development
    Use the automated svgdev tracks for positive resist.
  • 25. Positive Resist Photolithography
    Step 4: Postbaking (optional)
    If your positive resist is a mold for a channel that will have a valve or pump above it (like in this sample design), you should postbake it. This curves the cross-section, which allows for complete closure of the channel.
    120 ˚C, 5 min
    Postbakingshould be done at 120 ˚C for at least 5 min. Check the profile using a microscope.
    If no valve is employed, there is no need to postbake.