Applications of Bionanotechnology

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Applications of Bionanotechnology

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Applications of Bionanotechnology

  1. 1. Applications of Bionanotechnology<br />
  2. 2. Bionanotechnology<br /><ul><li> Bionanotechnology is a rapidly advancing area of scientific and technological opportunity that applies the tools and processes of nano/microfabrication to build devices for studying biosystems
  3. 3. Researchers learn from biology to create new micro-nanoscale devices to better understand life processes at the nanoscale
  4. 4. Bio-nanotechnology is concerned with molecular scale properties and applications of biological nanostructures and as such it sits at the interface between the chemical, biological and the physical sciences
  5. 5. Nanobiotechnology joins the breakthroughs in nanotechnology to those in molecular biology
  6. 6. Molecular biologists help nanotechnologists understand and access the nanostructures and nanomachines designed by 4 billion years of engineering - cell machinery and biological molecules</li></li></ul><li>Antibody-Nanoparticle Computational Modeling<br /><ul><li>The conjugation of antibodies and nanoparticles with high affinity & specificity through receptor ligand recognition modes is of paramount importance in the development of vehicles which can be used for diagnosis, treatment of cancer and various other diseases, application of immudiagnostic nano-biosensors etc.
  7. 7. The interfacial properties, especially the dynamic, thermodynamic, and mechanical properties, at different spatial and temporal resolutions of these bio-nano systems can be readily investigated with the aid of computer simulations, which consist of studies of interactions of the proteins as well as those of various nanomaterials with organic biological molecules such as proteins, nucleic acids, membrane lipids, and water</li></li></ul><li>Nanomedicines in Bionanotechnology<br /><ul><li>Nanomedicine is the medical application of nanotechnology that will hopefully lead to useful research tools, advanced drug delivery systems, and new ways to treat disease or repair damaged tissues and cells
  8. 8. Nanomedicines are the solution for poor bioavailability especially associated with RNA interference therapy
  9. 9. Lipid or polymer-based nanoparticles are taken up by cells due to their small size, rather than being cleared from the body. These nanoparticles can be used to shuttle drugs into cells which may not have accepted the drug on its own</li></li></ul><li>Molecular nanotechnology<br /><ul><li>Nanorobotics or molecular nanotechnology involves the creation of complex mechanical systems constructed from the molecular level
  10. 10. DNA makes an ideal material for the construction of nanomachines due to its stiffness.
  11. 11. The intermolecular interactions of DNA are well-known and can be easily predicted. The self-assembly of DNA further facilitates its use as a construction material</li></li></ul><li>Nanopore Technology<br /><ul><li>The biomolecular-nanopore detection technology was first developed to rapidly discriminate between nearly identical strands of DNA thereby replacing tedious process of running billions of copies of DNA through sequencing machines and thus minimize errors and save time
  12. 12. Single molecule of DNA is drawn through 1-2nm in size pores that serve as a sensitive detector
  13. 13. The biomolecular-nanopore detection technology has the potential to detect DNA polyploidy and DNA mutations</li></ul>Nanopore<br />
  14. 14. Nanoarrays<br /><ul><li> Dip pen nanolithography (DPN) that could probe complex mixtures of proteins, sense reactions involving the protein features and antigens in complex solutions, and study the details of cellular adhesion at the submicron scale
  15. 15. Protein nanoarrays generated by Dip-Pen Nanolithography are emerging and sooner would evolve into a much power tool in biotechnology
  16. 16. The development of miniaturization techniques like DPN enable the design of nanoarrays that can detect biological entities on a single-particle level in a timely and cost-efficient manner; also it would profile new diagnostic biomarkers at a detection level much beyond our imagination.</li></li></ul><li>Nanophotonics<br /><ul><li> Small-diameter “quantum” wires are ideal specimens for fundamental studies of two-dimensional (2D) quantum-confinement phenomena and for property comparisons to 3D-confined quantum dots, 1D-confined quantum wells and anisotropically 3D confined quantum rods.
  17. 17. Organic photovoltaics are nanostructured thin films composed of layers of semiconducting organic materials (polymers or oligomers) that absorb photons from the solar spectrum. These devices will revolutionize solar energy harvesting, because they can be manufactured via solution-based methods, such as ink-jet or screen printing, enabling rapid mass-production and driving down cost</li></li></ul><li>Nanotechnology and Tissue Engineering<br /><ul><li>Tissue engineering is one of the most fascinating directions of modern biotechnology.
  18. 18. The principle of the field of tissue engineering based on the ability to grow a network of cells, from patients themselves or donors, that will form functional tissues.
  19. 19. This tissue could be used later for transplantation in human patients. </li></li></ul><li>Nano Science and Technology Consortium<br />A-105, Level-III, Sector-63, <br />Noida-201301, U.P., (India).  <br />For Queries/Concerns  <br />Tel: +91-120- 4781215-17 Mob:+91-9818206463  <br /> Website: www.nstc.in <br />E-mail: info@nstc.in  <br /> Chat: Yahoo ID- nstcchat<br />

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