2. I’d like to talk about
• How many layers are there in the
• What are these layers made of ?
• What are their significant
What is this ….
4. 1.Largest organ
2.Also known as
5. Our skin are made of 3 basic
Epithermal layer of
A layer of mesodermal Beneath the dermis
6. 1st skin layer- Epidermis
Outermost layer of the skin
Have 4 different types of cells
But mainly are STRATIFIED SQUAMOUS KERATINIZED
EPITHILIUM – composed of cells called keratinocytes
The other NON-KERATINOCYTE CELLS
antigen-producing langerhans cells
tactile merkel cells
7. Layers of epidermis
Stratum granulosum – the granular layer
Stratum spinosum – the spinous layer
Stratum basale – the basal layer
8. WHAT IT DOES -
• Supports epidermis & binds it to the hypodermis
• Site for epidermal derivatives (e.g: hair follicles &
• irregular in shape & has many projections called Dermal
• Have abundance of nerve supply
Have BASEMENT MEMBRANE
• located in between the epidermis’s stratum basale &
dermis’s papillary layer.
• Composed of Basal Lamina and Reticular Lamina
• Important for nutrients to pass through from the
vascular dermis into the avascular epidermis.
Consists of 2 layers with indistinct
• OUTERMOST PAPILLARY LAYER
• Constitutes the major parts of the dermis
• Functions : produce anchoring – to be inserted into
basal lamina for the binding of dermis and epidermis
• DEEPER RETICULAR LAYER
• Thicker & composed of irregular dense CT
• Has more fibers than cells
• Present of elastic fiber to provide elasticityu
9. Dermal papillae
• Projections of dermal layers into the epidermis.
• Interlock with epidermal pegs
• It is more numerous in skin that is subjected to frequent
By increasing the epidermal-dermal junction
1. Consists of loose connective tissue – e.g: fat cells /
adipocytes (vary in number according to different region
of the body & vary in size according to the nutritional
2. Binds the skin loosely to the subjacent organs - This
enable the skin to slide over them.
3. Have an extensive vascular supply – promote rapid
uptake of insulin / drug injected into the tissue.