-GOVERNMENT SCIENCE COLLEGE
A cell that has the ability to
continuously divide and differentiate
(develop) into various other kind(s) of
Stem cells have the remarkable potential to develop
into many different cell types in the body during early life
Self-regeneration is the ability of stem cells to divide and
produce more stem cells. During early development, the
cell division is symmetrical and as well as a symmetrical.
The ability to differentiate is the potential to develop into
other cell types
1968 : Bone marrow transplant between two siblings
successfully treats SCID
1978 : Haematopoietic stem cell are discovered in
Human cord blood
1992 : Neural stem cell are cultured in vitro as
1997 : Leukemia is shown to originate from a
haematopoietic stem cell the first direct evidence for
cancer stem cell
1998 : James Thomson and coworkers derive the first
human embryonic stem cell line.
Kind of stem cell
cells are found
only in early
cell can form a
These cells are like
cells in that they
can give rise to all
cell can produce
only of a closely
related family of
Like a Muscle cell
,Liver cell ,Blood
What are embryonic stem cells?
Embryonic stem cell are stem derived from the inner cell
mass of a blastocyst ,an early stage embryo
These cells have the ability to self-renew through mitosis.
They are also pluripotent, which means they have the
potential to differentiate into a more specialized, mature
cell type performing distinct functions.
Adult stem cell
An adult stem cell is thought to be an undifferentiated
cell, found among differentiated cells in a tissue or
That can renew itself and can differentiate to yield some
or all of the major specialized cell types of the tissue or
Adult stem cells have been identified in many organs
there is a very small number of stem cells in each tissue,
and once removed from the body, their capacity to
divide is limited, making generation of large quantities of
stem cells difficult.
Application of stem cell
Sickle cell anemia
Stem cell treatments may require immunosuppression
because of a requirement for radiation before the
transplant to remove the patient's previous cells, or
because the patient's immune system may target the
Pluripotency in certain stem cells could also make it
difficult to obtain a specific cell type.
pluripotency is linked to tumor formation especially in
embryonic stem cells.