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In Vitro Fertilization
In Vitro Fertilization
In Vitro Fertilization
In Vitro Fertilization
In Vitro Fertilization
In Vitro Fertilization
In Vitro Fertilization
In Vitro Fertilization
In Vitro Fertilization
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In Vitro Fertilization

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  • 1. In Vitro Fertilization
  • 2. What is In Vitro Fertilization (IVF)?
    • Process by which egg cells are fertilized by sperm outside of the womb
    • Major treatment for infertility
    • Process involves hormonally controlling ovulation, removing eggs from the ovaries and letting sperm fertilize the eggs in a fluid medium  fertilized egg (zygote) is transferred to woman’s uterus
  • 3. Method
    • Ovarian Stimulation
    • Treatment starts on the third day of menstruation
    • Fertility medications are administered – 10 days of injections are necessary
  • 4. Method
    • 2. Egg Retrieval
    • Eggs are retrieved using a transvaginal technique using a needle to pierce the vaginal walls (to reach the ovaries)
    • 10 to 30 eggs are removed
  • 5. Method
    • 3. Fertilization
    • Sperm and egg are incubated together (at a ratio of 75 000:1) for about 18 hours
    • The fertilized egg is put in a special growth medium and left for about 48 hours until it has reached the 6-8 cell stage
  • 6. Method
    • 4. Embryo Transfer
    • The “best” embryos are transferred to the uterus using a thin, plastic catheter – which goes through the vagina and cervix
    • Some embryos may be passed into the uterus to improve changes of pregnancy
  • 7. For IVF to be Successful …
    • Need healthy ova (egg)
    • Healthy sperm – that can fertilize
    • Uterus – that can maintain a pregnancy
    • IVF can be used for females who have already gone through menopause
  • 8. Success Rate
    • Pregnancy rate = success rate for pregnancy
    • For IVF, success rate is the percentage of all attempts that lead to pregnancy
    • In 2006, Canadian clinics reported an average pregnancy rate of 35% and a live birth rate of 27%
  • 9. Complications
    • Major complication is risk of multiple births – related to the practice of transferring multiple embryos at embryo transfer
    • Multiple births – related to increased risk of pregnancy loss, obstetrical complications, prematurity, and death

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