1. RESPIRATIO
NB M Subramanya Swamy M.Sc. B.Ed.
CIE Co ordinator & Examination Officer
Kanaan Global School
Jakarta
Indonesia
swamy@kanaanglobal.sch.id
2. Introduction
• Energy is needed for cellular respiration
• Food is in the source of energy for human
• Oxygen is needed to release this energy from
food
• Respiration is the process by which the body
obtains and utilises oxygen and eliminates
carbon dioxide
3. The three process of respiration in human
Process Mode of action
Breathing Involves external respiratory system to
take in O2 and release CO2
Internal
respiration
Exchange of substances between
capillaries and cells
Cellular
respiration
Release of energy from food substances
in living cells
4. CELLULAR RESPIRATION
the release of energy from food substances in all living cell
Comparison of aerobic and anaerobic respiration
Aerobic Anaerobic
Oxygen Present Absent
Energy from
breakdown of food
Large amount Relatively small
Location Begins in cytoplasm and
continues into the
mitochondria
In cytoplasm
Efficiency Very good
36 molecules of ATP
from 1 glucose molecule
Inefficient
2 molecules of ATP
from 1 glucose
molecule
Example of organism All organisms and some
yeast
Yeast, bacteria, seals
and whales ( animals
that dive deep into the
ocean)
5. Aerobic Respiration
C6H12O6 + 6O2 6CO2 + 6H2O + ENERGY
Uses of aerobic respiration in human
Uses of energy Mode of action
Muscle contraction For muscular contractions, cardiac muscles and
peristalsis
Protein synthesis Formation of peptide bonds
Cell division Growth, synthesis of chromosomes, cell membrane,
etc.
Active transport Transport of substances across a concentration
gradient
Growth New protoplasm, and in metabolic processes
Transmission of nerve
impulse
Along the axon, and for the transport of sodium
ions out
Regulation of body
temperature
Energy released to keep the body warm
6. Anaerobic Respiration
Anaerobic respiration and its uses
Types Mode of action
Alcoholic fermentation (in
plants)
• Incomplete breakdown of sugar to release
energy
• Glucose ethanol + CO2 + energy (2 ATP)
• Economically important, e.g. in bread making,
brewing of beer and wine
Lactic acid fermentation
(in man and animal)
{ Some bacteria causes milk to turn sour and
form yoghurt
{ The bacteria feeds on sugar
{ Glucose lactic acid + energy (2 ATP)
7. Anaerobic respiration and its uses
Types Mode of action
During rigorous muscular
activity
¶During strenuous activity, breathing is not
enough to provide O2 for respiration
¶Muscles experience a shortage of O2,
causing formation of lactic acid
¶Accumulation of lactic acid causes
muscular cramp and fatigue
¶Muscle experiences O2 debt during
periods of anaerobic respiration
¶Rapid breathing helps to repay the debt
by increasing O2 in the muscles, thus
converting lactic acid back to glucose
8. GASEOUS EXCHANGE IN MAN
• Lungs are the main respiratory organ in human
• They lie in the upper chest cavity
• Lungs are divided into section called lobes
• Air enters through nostril, into nasal passages,
pharynx, larynx, trachea, bronchi and bronchioles
before entering the alveoli
9. Components of respiratory organs and its function
Organs Function
Nostrils Projecting nasal hairs filter out dust and debris
Nasal cavity üDivided by septum
üLined with ciliated epithelium
üBlood vessels below epithelium warms the air
Pharynx § Both air and food passage
§ Warms, moistens and filters air
Glottis Guarded by epiglottis (elastic flap at entrance of
trachea)
Larynx Has vocal cord
Trachea ÆCylindrical tube with rings of cartilage to provide
support
ÆLayer of cilia and mucus – secreting cells
ÆTraps debris and sweeps it upwards towards
the mouth
ÆDivided to form two bronchi
10.
11. Components of respiratory organs and its functions
Organs Function
Lung JRich in blood supply, site of gaseous exchange
JLeft lung has two lobes
JRight lung is bigger, with three lobes
Bronchus Divided into smaller tubes called bronchioles
Plural membrane Encloses each lung
Diaphragm TMuscular tissue attached to thoracic cavity
TSeparates thoracic cavity from abdominal cavity
TThoracic cavity changes volume to assist in
breathing
Bronchiole {Connects directly to alveoli
{Widens and narrows during breathing
Alveoli ØAir sacs with thin wall with a moist surface
ØA network of blood capillaries covers the alveoli
13. Comparison of inspiration and expiration
Inspiration Expiration
J External intercostal muscle
contracts
J Increase in volume of thoracic
cavity
J Ribs swing upwards and
outwards
J Diaphragm contracts, flattens
down
J An increase in thoracic cavity
volume reduces air pressure in
the cavity and lungs. Gases
expand to fill the available space,
creating a partial vacuum. This
forces air into the lungs.
ü Internal intercostal muscle
contracts
ü Reduction in volume of thoracic
cavity
ü Ribs swing downwards and
inward
ü Diaphragm is relaxed and
elevated
ü A reduction in the volume of
thoracic cavity increases air
pressure. This forces air out of
the lungs to equalise the
pressure of the lungs with the
atmosphere.
15. Comparison of composition inhaled and exhaled
air
Inhaled air Exhaled air
Oxygen 21% 17%
Carbon dioxide < 0.1% 4%
Nitrogen 79% 79%
Temperature Room temperature 37°C
Moisture Variable 100%
Dust Variable Absent
16. Control of Breathing
• The respiratory center is located in the lower
medulla oblongata
• The stimulus for the respiratory center is the
presence of CO2
• When CO2 level increases, breathing rate increases as
well
• During anxiety or anger, the hormone adrenaline
increases metabolic rate and breathing
• If the levels drop, it inactivates the respiratory center.
This could lead to death.
17.
18. Adaptations of alveoli and blood capillaries
for exchange of gases
Adaptation Mode of action
Network of blood capillaries For transport of gases to and from
alveoli
Large surface area Allows for increased rate of diffusion
Moist surface of alveoli Allows gases to dissolve before
diffusion occurs
Concentration gradient Increased rate of diffusion
Distance between alveoli and blood
capillaries
Short distance increases rate of
diffusion
Wall of alveoli and blood capillaries One cell thick : faster diffusion
19.
20. Internal Respiration
• This is the exchange of gases between blood
and body tissues
• Carbon dioxide is carried as carbamino
haemoglobin or bicarbonate ions
Hb + CO2 carbamino haemoglobin
CO2 + H2O H2CO3
H2CO3 H+ +HCO3
-
21. Passage of Gases
Oxygen Carbon dioxide
During inspiration, O2 diffuses
across the alveolus
During expiration, CO2 is expelled
with water vapour from the lungs
It enters the blood stream There is a higher concentration of
deoxygenated blood in this area
98% combines with blood to
form oxyhaemoglobin
It is carried in the blood as
bicarbonate ions and carbamino
haemoglobin
< 2% enters the plasma It diffuses out of capillary into the
alveoli
22.
23.
24. 23-24
Pulmonary Volumes
• Tidal volume
– Volume of air inspired or expired during a normal inspiration or
expiration
• Inspiratory reserve volume
– Amount of air inspired forcefully after inspiration of normal tidal
volume
• Expiratory reserve volume
– Amount of air forcefully expired after expiration of normal tidal
volume
• Residual volume
– Volume of air remaining in respiratory passages and lungs after the
most forceful expiration
25. 23-25
Pulmonary Capacities
• Inspiratory capacity
– Tidal volume plus inspiratory reserve volume
• Functional residual capacity
– Expiratory reserve volume plus the residual volume
• Vital capacity
– Sum of inspiratory reserve volume, tidal volume, and expiratory
reserve volume
• Total lung capacity
– Sum of inspiratory and expiratory reserve volumes plus the tidal
volume and residual volume
27. 23-27
Respiratory System Functions
• Gas exchange: Oxygen enters blood and carbon
dioxide leaves
• Regulation of blood pH: Altered by changing blood
carbon dioxide levels Carbonic acid Buffer system
• Sound production: Movement of air past vocal folds
makes sound and speech
• Olfaction: Smell occurs when airborne molecules
drawn into nasal cavity
• Thermoregulation: Heating and cooling of body
• Protection: Against microorganisms by preventing
entry and removing them
