Lacking Telomeres May Make You Age Faster

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Lacking Telomeres May Make You Age Faster

  1. 1. Lacking Telomeres May Make You Age Faster By Dana Berger and Clay Walsh
  2. 2. Researching Telomeres -Scientists at the University of Leicester might have discovered why some people look older than they actually are by researching Telomeres Telomeres= are pieces of DNA at the ends of chromosomes that protect the chromosome from damage. - As cells divide telomeres shrink, and scientists think that is the cause of biological aging.
  3. 3. Whats the difference between biological and chronological aging? -Biological aging is the physical state of your cells after they split -Chronological aging is how long you have actually lived -scientists say that someone who is 40 years old who has small telomeres may have a biological age of a 50 year old
  4. 4. Variations in Telomeres Length - Scientist Nilesh Samani studied 500,000 genetic variations to find telomere length difference in the variations - Scientists did in fact find a variant that causes some people to have shorter telomeres - The variant is genetic
  5. 5. Tests on animals -Scientists examined animals with shorter telomeres and these animals showed faster biological aging -Scientists say that on average people with one copy of the variant are 4-5 biological years older then the same chronological age without the variant -They also say that on average people with 2 copies of the variant are 6-8 biological years older then the same chronological age without the variant
  6. 6. Concerns with shorter telomeres - Samani is also a cardiologist and brought up concerns about how shorter telomeres can bring up early heart disease -He says people who are chronologicaly older may have better health then someone chronologicaly younger -This is dangerous because someone can think they are healthy but can actually be at risk
  7. 7. Can you tell from looks who is bilogically older? -Scientists are interested in seeing if you can identify people who are biologically older by appearance -At this point in time, the scientists are unsure if you can, and are trying to develop a way to test that
  8. 8. Acknowledgments 1. Scientific American for posting the original article http://www.scientificamerican.com/article.cfm?id=aging-telomere

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