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Blood composition

Blood composition






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    Blood composition Blood composition Presentation Transcript

    • BLOOD
    • Vasular System
      • Made up of blood vessels that carry blood
    • Blood is considered a tissue!
      • Aggregation of cells that are similar in structure and function. Cells do not need to be identical, but from the SAME origin that carry out a specific function.
    • Average Adult
      • Male: 5-6 L
      • Female: 3-5 L
    • Blood Composition Blood Plasma (55%) Cells (45%) RBC (44%) WBC Platelets 1% serum Water (92%) Proteins Lymphocyte macrophage Others
    • Red Blood Cells
      • Made in the bone marrow
    • Structure
      • Erythrocytes – 99% of cells
      • Mature RBC has no nucleus
      • Hemoglobin – iron containing
      • molecule that binds to oxygen.
      • 5.5 million/mL – males
      • 4.5 million/mL - females
    • Function
      • Hemoglobin contains four iron atoms that are each part of a heme group.
      • Four molecules of oxygen attach to one molecule of hemoglobin
      • One RBC contains 280 million molecules of hemoglobin.
      • RBC live 3-4 months. They go to the liver where iron is recycled.
    • Platelets
      • Made in the bone marrow
    • Structure
      • No nucleus
      • Fragments of cells
      • Live about 7-10 days
      • Makes up 0.6 – 1 %
    • Function
      • Clot blood
      • Protect body from excessive blood loss.
      • Process: Activated by injury. They collect at site.
      • Chemicals react and produce thromboplastin
      • Thromboplastin reacts with prothrombin to produce thrombin (need calcium).
      • Thrombin reacts with fibrinogen to produce fibrin
      • This creates a mesh to stop cells from escaping.
    • Clot
    • Monocyte/Macrophage
      • Cell Type - Phagocytic cells
      • Function – digest pathogens
      • Immune response: Innate (no immunological memory)
    • Lymphocyte
      • Cell type – non phagocytic cells (T-cells – mature in the thymus and B cells mature in the bone marrow)
      • Function – Recognize pathogen
      • Immune response – Acquired (exposure of pathogen leads to an immunological memory)
    • Serum
      • Serum Albumin – maintains blood volume and blood pressure.
      • Serum Globulin – a number of protein components that act to defend the body against disease.
    • Antigen
      • Two Definitions
      • Invader
      • Protein found on the blood
    • O AB B A Antibodies (present in plasma) Antigen (Present on blood cell) Blood Type
    • Agglutination
      • Clumping of RBC due to the mixture of different blood groups. The antibodies recognize the unfamiliar antigens and bind to it, causing them to clump.
    • Rh Factor
      • Another antigen on the RBC.
    • Antibody
      • Protein in blood plasma, which recognizes the antigen of foreign blood or substance in the body