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*Antibiotics: Are chemicals produced by microorganisms that inhibit the growth of other microorganisms. **Chemotherapeutic agent: (Synthetic versions ).
ANTIBIOTIC TYPES: 1-BOARD SPECTRUM ANTIBIOTICS:- This against wide range of both G+ve and G-ve bacteria . 2-Narrow spectrum antibiotics : This against selective groups of organisms
MODE OF ACTIONS OF ANTIBIOTICS: 1-Distruptions of cell wall synthesis . 2-Distruptions of cell membrane function 3-Inhibition of protein synthesis 4- Inhibition of nucleic acid synthesis 5-Competitive Inhibition of metabolic pathways.
** Drug resistance ?? Procedure for antibiotic sensitivity test : 1-Diffusion method (Kirby Baur disk diffusion) 2-Pour plate Method. The Kirby procedure used to determine the effect of the drug on the bacterial growth.
R: RESISTANCE S:SENSETIVE I:INTERMEDIATE R S SENSETIVE ZONE