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Leptin and obesity cycle
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Leptin and obesity cycle

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How fat is managed in our human body , and how by altering the leptin pathway we can treat bulimia, anorexia and obesity like disorders.

How fat is managed in our human body , and how by altering the leptin pathway we can treat bulimia, anorexia and obesity like disorders.

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    Leptin and obesity cycle Leptin and obesity cycle Presentation Transcript

    • LEPTIN & OBESITYDr. Smrutiranjan Patanaik
    •  OBESITY – A GLOBAL HEALTH PROBLEM RECENT LIPOSTATIC HYPOTHESIS HAS GIVEN ATTENTION TO LEPTIN DEFECTIVE OB/OB GENE IN MICE REVEALS ASSOCIATION OF LEPTIN WITH OBESITY KNOCKOUT OF DB/DB GENE PRODUCES DECREASE IN LEPTIN RECEPTORS LEPTIN RESISTANCE IS ASSOCIATED WITH OBESITY
    •  A PEPTIDE HORMONE 167 AMINO ACIDS M.wt. 16kDa SECRETED BY ADIPOCYTES DISCOVERED BY FRIEDMAN IN 1994
    •  LEPTIN OPERATES AS PART OF A FEEDBACK LOOP BY WHICH THE SIZE OF THE BODY FAT DEPOTS CAN OPERATE THROUGH A HUMORAL LINK TO REGULATE FOOD INTAKE
    • THANK YOU