Inflammatory & Degenerate Bone and Joint Diseases By  Dr. Abdullah H.A. Juma FRCSEd. Associate Professor & Consultant Orth...
Inflammatory Disorders <ul><li>Introduction  : </li></ul><ul><li>Those conditions are characterized by the presence of inf...
<ul><li>Pathophysiology  : </li></ul><ul><li>Age .. Any age but commonly middle aged patients. </li></ul><ul><li>Sex .. Fe...
<ul><li>Types of inflammatory disorders : </li></ul><ul><li>Rheumatoid Arthritis. </li></ul><ul><li>Seronegative Arthritis...
Rheumatoid Arthritis <ul><li>Age.. Middle aged. </li></ul><ul><li>Sex.. F : M = 2.5 : 1 .Unknown ,but likely to be hormona...
American Rheumatism Association criteria for the diagnosis of rheumatoid arthritis <ul><li>Morning stiffness. </li></ul><u...
Pathogenesis of Rh.A. <ul><li>3 stages are noted : </li></ul><ul><li>Synovitis.. Cellular & enzymatic with/or without syno...
Clinical presentation of Rh.A. <ul><li>Slowly progressive polyarthritis. </li></ul><ul><li>Episodic polyarthritis. </li></...
Upcoming SlideShare
Loading in …5
×

Inflammatory & Degenerate Bone And Joint Diseases

5,192 views

Published on

Published in: Health & Medicine
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
5,192
On SlideShare
0
From Embeds
0
Number of Embeds
34
Actions
Shares
0
Downloads
134
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Inflammatory & Degenerate Bone And Joint Diseases

  1. 1. Inflammatory & Degenerate Bone and Joint Diseases By Dr. Abdullah H.A. Juma FRCSEd. Associate Professor & Consultant Orthopaedic Surgeon
  2. 2. Inflammatory Disorders <ul><li>Introduction : </li></ul><ul><li>Those conditions are characterized by the presence of inflammation and NOT infection. </li></ul><ul><li>They affect primarily the joints. Bones are affected secondarily and to a lesser degree. </li></ul>
  3. 3. <ul><li>Pathophysiology : </li></ul><ul><li>Age .. Any age but commonly middle aged patients. </li></ul><ul><li>Sex .. Female show slight increase in incidence. </li></ul><ul><li>Causes .. Not clearly known but genetic and environmental factors are well observed. Possible viral provacation is there. </li></ul><ul><li>Target organs .. Synovium , tendon sheaths. </li></ul>
  4. 4. <ul><li>Types of inflammatory disorders : </li></ul><ul><li>Rheumatoid Arthritis. </li></ul><ul><li>Seronegative Arthritis.. </li></ul><ul><li>Posriasis. </li></ul><ul><li>Ankylosing Spondylitis. </li></ul><ul><li>Reiter’s disease. </li></ul><ul><li>Behcet’s disease. </li></ul><ul><li>Enteropathic Arthritis. </li></ul><ul><li>Systemic Lupus Erythematosis. </li></ul><ul><li>Scleroderma (Progressive Systemic Sclerosis ). </li></ul><ul><li>Polyarteritis Nodosa. </li></ul><ul><li>Polymyositis & Dermatomyositis. </li></ul>
  5. 5. Rheumatoid Arthritis <ul><li>Age.. Middle aged. </li></ul><ul><li>Sex.. F : M = 2.5 : 1 .Unknown ,but likely to be hormonally related. </li></ul><ul><li>Onset.. Gradual , on & off with acute relapses. </li></ul><ul><li>Systemic manifestations but early presentation of local problem is common. </li></ul><ul><li>Syemmetrical polyarthritis is the classical mark. </li></ul>
  6. 6. American Rheumatism Association criteria for the diagnosis of rheumatoid arthritis <ul><li>Morning stiffness. </li></ul><ul><li>Pain on motion or tenderness in a joint. </li></ul><ul><li>Swelling of joint due to fluid or soft tissue. </li></ul><ul><li>Swelling of a second joint. </li></ul><ul><li>Symmetrical joint swelling,ie.Rt&Lt. </li></ul><ul><li>Typical rheumatoid nodules. </li></ul><ul><li>Xray finding of peri-articular osteopenia. </li></ul><ul><li>Rheumatoid factor is positive. </li></ul><ul><li>Synovial fluid form poor mucin clot with acetic acid. </li></ul><ul><li>Characteristic synovial histology. </li></ul><ul><li>Characteristic histology of rheumatoid nodule. </li></ul>
  7. 7. Pathogenesis of Rh.A. <ul><li>3 stages are noted : </li></ul><ul><li>Synovitis.. Cellular & enzymatic with/or without synovial thickening. Pannus formation can occur. </li></ul><ul><li>Destruction.. Joint , soft tissues. </li></ul><ul><li>Deformity.. With sublaxation or dislocation. </li></ul>
  8. 8. Clinical presentation of Rh.A. <ul><li>Slowly progressive polyarthritis. </li></ul><ul><li>Episodic polyarthritis. </li></ul><ul><li>Mono-articular or Oligo-articular arthritis. </li></ul><ul><li>Fulminating polyarthritis. </li></ul>

×