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Operating Plan Process - Timing and Milestones




                                        Input from
Identificati    Priorities                                        Operating
                              Global      Markets    Lifecycle
   on of          Walk -
                  Walk-
                             Product        MM       planning        Plan
 Priorities     Through
                             Platform     Meeting      (3/31)    Presentation
and Issues     Presentatio
                              (3/24)       (3/22)                (6/3 – 6/13))
   (2/1)         n (3/2)




                             WW Operating Plan
Op Plan - Drive Focus on Business Needs & Alignment

                Jan                Feb         Mar                Apr      May        June                 July

                                                 PGP                       PGP
   PGP
                                                 AST                       AST
Alignment
                                                              Regional                                     Regional
                                                              Priorities                                   Priorities
                                                              Meeting                                      Meeting
                                           WW                                    Submit Budgets
                                         Priorities
                                                                                  WW Op Plan
   WW                                    Walk-Thru
                                                                                 Presentations
               Prod Dev Plans,
 Deliver-      Lifecycle Invent,                                                       WW Prioritization
                                                     GPP &
  ables             & GTAP                       Lifecycle Plan
                                                                                          Exercise




            • Priorities Walkthrough is Critical
                – Opportunity to present critical thinking on business needs
                – Need to identify support options and flag resource
                  requirements


   GABY: Please take these dates and
    GABY: Please take these dates and
   milestones out of this format put this on
    milestones out of this format put this on                              What Slide 18?
   aatimeline like the one on slide #18
                                                                           What Slide 18?
      timeline like the one on slide #18
Inspra Key Events
                       France & Spain REMODEL
                           Launch
Internal




           US, Mexico,                 MOA Trial
           Netherlands     2Q-3Q         results
              , UK,
                          Australia  Japan & Italy                 Mild-moderate
            Germany
                           Launch       Launch                        CHF trial    FDC
            Launches
                             4Q           1Q                         results 2Q  approval

             2004          2005             2006     2007   2008      2009        2010      2011
External




                        • 30-day data
                          and Circulation
                          supplement
                          published
                        • HFSA, AHA,
                         and ESC
                                                                    Potential LOE in US
                         Guidelines

                        Atacand CHF
                          approval
Strategic Scenario Evaluation

            Inspra/diuretic fixed dose combination

    Scenario #1        Scenario #2        Scenario #3
  Maintain Current    Resistant HTN        Eliminate
     Direction           Upside           WWT Support




                        Brand Options

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Medical Sample 11

  • 1. Operating Plan Process - Timing and Milestones Input from Identificati Priorities Operating Global Markets Lifecycle on of Walk - Walk- Product MM planning Plan Priorities Through Platform Meeting (3/31) Presentation and Issues Presentatio (3/24) (3/22) (6/3 – 6/13)) (2/1) n (3/2) WW Operating Plan
  • 2. Op Plan - Drive Focus on Business Needs & Alignment Jan Feb Mar Apr May June July PGP PGP PGP AST AST Alignment Regional Regional Priorities Priorities Meeting Meeting WW Submit Budgets Priorities WW Op Plan WW Walk-Thru Presentations Prod Dev Plans, Deliver- Lifecycle Invent, WW Prioritization GPP & ables & GTAP Lifecycle Plan Exercise • Priorities Walkthrough is Critical – Opportunity to present critical thinking on business needs – Need to identify support options and flag resource requirements GABY: Please take these dates and GABY: Please take these dates and milestones out of this format put this on milestones out of this format put this on What Slide 18? aatimeline like the one on slide #18 What Slide 18? timeline like the one on slide #18
  • 3. Inspra Key Events France & Spain REMODEL Launch Internal US, Mexico, MOA Trial Netherlands 2Q-3Q results , UK, Australia Japan & Italy Mild-moderate Germany Launch Launch CHF trial FDC Launches 4Q 1Q results 2Q approval 2004 2005 2006 2007 2008 2009 2010 2011 External • 30-day data and Circulation supplement published • HFSA, AHA, and ESC Potential LOE in US Guidelines Atacand CHF approval
  • 4. Strategic Scenario Evaluation Inspra/diuretic fixed dose combination Scenario #1 Scenario #2 Scenario #3 Maintain Current Resistant HTN Eliminate Direction Upside WWT Support Brand Options