Red Wine and Breast Cancer

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A research project and presentation I worked on in my Medical Nutrition Therapy class, which discusses the link between moderate consumption of red wine and its effect on breast cancer

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Red Wine and Breast Cancer

  1. 1. Cristi Ambroso Erin Ducker Julia SimonLauren Walker
  2. 2.  Hypothesis Introduction Body of Knowledge  Polyphenols  Estrogen  Phytoestrogens Studies Conclusion Implications Recommendations Trials and Tribulations Quiz
  3. 3.  Moderate Consumption of Red Wine Reduces the Risk of Breast Cancer
  4. 4.  1 in 8 women will get breast cancer during their lifetime Based on this statistic, 10 people in HNF 320 will develop breast cancer in their lifetime 1/3 of cancers are linked to diet 3-4 million cancer cases can be prevented each year by change in diet Grapes are most widely consumed fruit worldwide  Contain polyphenols
  5. 5.  Antioxidants found in the seeds, skins, and stems of grapes Beneficial health effects including inhibiting cancer growth Resveratrol is a powerful polyphenol in red wine and prevents tumor growth
  6. 6.  Estrogen: hormone that contributes to normal breast and sexual development Estrogenstimulates cell division, meaning excessive amounts can lead to tumor development Polyphenols decrease estrogen levels Phytoestrogens are estrogens found in plants
  7. 7.  Commonly found in tofu, soy beans, whole grains, fruits, and vegetables Diethigh in phytoestrogens can decrease one’s risk for breast cancer  If phytoestrogens bind to the estrogen receptor instead of the stronger human made estrogen less cell division will occur
  8. 8.  Objective: To determine the anti-proliferative affect of red wine concentrate on the hormone sensitive breast cancer cells Results: Low concentrations of polyphenols, and consecutively, consumptions of wine or other polyphenol rich foods and beverages could have a beneficial anti-proliferative affect on breast cancer cell growth
  9. 9.  Objective: To determine whether Resveratrol may be considered a phytoestrogen Researchers found resveratrol binds to the human estrogen competeing with human made estrogen Results: Resveratrol is a phytoestrogen, meaning Resveratrol plays a role in reducing breast cancer risk
  10. 10.  Objective: To determine whether Resveratrol can be a cancer chemopreventive agent Used a mouse mammory gland culture model of carcinogenesis to test activity resveratrol Results: found to inhibit tumor initiation, promotion, and progression
  11. 11.  Positive correlation between red wine consumption and decrease breast cancer risk  Hypothesis is accepted Polyphenols have been shown to be beneficial in decreasing breast cancer risk More research is needed, especially clinical trials involving humans
  12. 12.  Moderate consumption of red wine can be beneficial Grapes contain the polyphenols, not alcohol Eating grapes or drinking 100% natural grape juice can offer similar protection against breast cancer
  13. 13.  Bothmen and women should have a diet rich in polyphenols (antioxidants)
  14. 14.  Rewards:  Became knowledgeable on importance of diet with breast health  Became more familiar with researching Challenges:  Difficult to compile all of our information  Interpreting the research articles
  15. 15.  Polyphenols are  A. Grapes  B. Antioxidants  C. A type of wine  D. Cancer causing substance B. Antioxidant
  16. 16.  True or false  Resveratrol is a human made estrogen

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